| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Brain Injuries | D001930 | 4 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Osteonecrosis | D010020 | 5 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
Platelet activating factor
Platelet activating factor is a lipid of Glycerophospholipids (GP) class. Platelet activating factor is associated with abnormalities such as Atherosclerosis, Acute cholecystitis without calculus, Cholecystitis, Colitis and Cholecystitis, Acute. The involved functions are known as Cell Survival, Metabolic Inhibition, lipid oxidation, Apoptosis and Oxidation. Platelet activating factor often locates in soluble, Cellular Membrane, Smooth muscle (tissue), Intima and Tissue specimen. The associated genes with Platelet activating factor are apolipoprotein A-I Milano, Homologous Gene, TSPO gene, HBEGF gene and SLC33A1 gene. The related lipids are Hydroxycholesterols, Liposomes, 25-hydroxycholesterol, Lysophosphatidylcholines and Lipopolysaccharides. The related experimental models are Knock-out, Mouse Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Platelet activating factor, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Platelet activating factor?
Platelet activating factor is suspected in Ischemia, Pleurisy, Atherosclerosis, Inflammatory disorder, Retinal Diseases, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Platelet activating factor
PubChem Associated disorders and diseases
What pathways are associated with Platelet activating factor
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Platelet activating factor?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Platelet activating factor?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Platelet activating factor?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Platelet activating factor?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Platelet activating factor?
Knock-out
Knock-out are used in the study 'A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.' (Leary PJ et al., 2008).
Mouse Model
Mouse Model are used in the study 'A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.' (Cheng L et al., 2009).
Transgenic Model
Transgenic Model are used in the study 'Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons.' (Ryan SD et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Platelet activating factor
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nimjee SM et al. | Translation and Clinical Development of Antithrombotic Aptamers. | 2016 | Nucleic Acid Ther | pmid:26882082 |
| Vadas P | The platelet-activating factor pathway in food allergy and anaphylaxis. | 2016 | Ann. Allergy Asthma Immunol. | pmid:27788869 |
| Wang M et al. | The responses of pulmonary and systemic circulation and airway to anaphylactic mediators in anesthetized BALB/c mice. | 2016 | Life Sci. | pmid:26808090 |
| Bihl JC et al. | UVB Generates Microvesicle Particle Release in Part Due to Platelet-activating Factor Signaling. | 2016 | Photochem. Photobiol. | pmid:26876152 |
| Reiner B et al. | Platelet-activating factor attenuation of long-term potentiation in rat hippocampal slices via protein tyrosine kinase signaling. | 2016 | Neurosci. Lett. | pmid:26808643 |
| Unsal E et al. | Effects of pentoxifylline and platelet activating factor on sperm DNA damage. | 2016 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:26748389 |
| Kim HK et al. | Glutamine Prevents Late-Phase Anaphylaxis via MAPK Phosphatase 1-Dependent Cytosolic Phospholipase A2 Deactivation. | 2016 | Int. Arch. Allergy Immunol. | pmid:27838690 |
| Sahu RP et al. | Systemic chemotherapy is modulated by platelet-activating factor-receptor agonists. | 2015 | Mediators Inflamm. | pmid:25922565 |
| Shida-Sakazume T et al. | Lysophosphatidylcholine acyltransferase1 overexpression promotes oral squamous cell carcinoma progression via enhanced biosynthesis of platelet-activating factor. | 2015 | PLoS ONE | pmid:25803864 |
| Lautenschläger I et al. | Quinidine, but not eicosanoid antagonists or dexamethasone, protect the gut from platelet activating factor-induced vasoconstriction, edema and paralysis. | 2015 | PLoS ONE | pmid:25793535 |
| Bate C and Williams A | α-Synuclein-induced synapse damage in cultured neurons is mediated by cholesterol-sensitive activation of cytoplasmic phospholipase A2. | 2015 | Biomolecules | pmid:25761116 |
| Sahu RP | Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cells. | 2015 | Mol Med Rep | pmid:25695262 |
| Reznichenko A and Korstanje R | The role of platelet-activating factor in mesangial pathophysiology. | 2015 | Am. J. Pathol. | pmid:25655028 |
| Jeewandara C et al. | Platelet activating factor contributes to vascular leak in acute dengue infection. | 2015 | PLoS Negl Trop Dis | pmid:25646838 |
| Valli A et al. | Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways. | 2015 | Oncotarget | pmid:25605240 |
| Sun L et al. | PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer. | 2015 | Int J Clin Exp Pathol | pmid:25755731 |
| Wang Y et al. | Aqueous extract of Rabdosia rubescens leaves: forming nanoparticles, targeting P-selectin, and inhibiting thrombosis. | 2015 | Int J Nanomedicine | pmid:26604756 |
| van Doorn R and de Gruijl F | Chromatin Modifications and Mast Cell Migration in UV-Induced Immunosuppression, an Epigenetic Piece of The Puzzle. | 2015 | J. Invest. Dermatol. | pmid:26569583 |
| Pałgan K and Bartuzi Z | Platelet activating factor in allergies. | 2015 | Int J Immunopathol Pharmacol | pmid:26486136 |
| Hergott CB et al. | Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection. | 2015 | J. Clin. Invest. | pmid:26426079 |