4-METHYLPENTANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as CoA-transferase activity. 4-methylpentanoic acid often locates in Cytosol. The related lipids are Fatty Acids and alpha-ketocaproic acid.
To understand associated biological information of 4-METHYLPENTANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 4-METHYLPENTANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Clostridium Infections | D003015 | 5 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Edema | D004487 | 152 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Okada K et al. | Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme. | 2001 | Biochemistry | pmid:11412098 |
| Crespo-Facorro B et al. | Neural mechanisms of anhedonia in schizophrenia: a PET study of response to unpleasant and pleasant odors. | 2001 | JAMA | pmid:11466121 |
| Calzada L et al. | Measurement of androgen and estrogen receptors in breast tissue from subjects with anabolic steroid-dependent gynecomastia. | 2001 | Life Sci. | pmid:11554608 |
| St-Onge MP et al. | Kefir consumption does not alter plasma lipid levels or cholesterol fractional synthesis rates relative to milk in hyperlipidemic men: a randomized controlled trial [ISRCTN10820810]. | 2002 | BMC Complement Altern Med | pmid:11825344 |
| Loganath A et al. | Evidence for the biosynthesis of DHEA from cholesterol by first-trimester human placental tissue: source of androgens. | 2002 | Horm. Metab. Res. | pmid:11972299 |
| Halvatsiotis PG et al. | Insulin effect on leucine kinetics in type 2 diabetes mellitus. | 2002 | Diabetes Nutr. Metab. | pmid:12173727 |
| Tokuda C et al. | Conversion of Lactobacillus pentosus D-lactate dehydrogenase to a D-hydroxyisocaproate dehydrogenase through a single amino acid replacement. | 2003 | J. Bacteriol. | pmid:12897026 |
| SHIMIZU K et al. | Isocaproic acid, a metabolite of 20 alpha-hydroxycholesterol. | 1960 | J. Biol. Chem. | pmid:14446007 |
| MARTIN WR et al. | beta-Carboxy-beta-hydroxy-isocaproic acid formation by microorganisms. | 1962 | Biochim. Biophys. Acta | pmid:14470457 |
| Nakai T et al. | Ligand-induced conformational changes and a reaction intermediate in branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8, as revealed by X-ray crystallography. | 2004 | J. Mol. Biol. | pmid:15033367 |
| Ohta K et al. | Application of polymethacrylate resin as stationary phase in liquid chromatography with UV detection for C1-C7 aliphatic monocarboxylic acids and C1-C7 aliphatic monoamines. | 2004 | J Chromatogr A | pmid:15250419 |
| Ohta K et al. | Separation and conductimetric detection of C1-C7 aliphatic monocarboxylic acids and C1-C7 aliphatic monoamines on unfunctionized polymethacrylate resin columns. | 2004 | J Chromatogr A | pmid:15250420 |
| Broadbent JR et al. | Overexpression of Lactobacillus casei D-hydroxyisocaproic acid dehydrogenase in cheddar cheese. | 2004 | Appl. Environ. Microbiol. | pmid:15294819 |
| Venos ES et al. | Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis. | 2004 | BMC Microbiol. | pmid:15471546 |
| Colombo D et al. | Anti-tumor-promoting activity of simple models of galactoglycerolipids with branched and unsaturated acyl chains. | 2005 | Eur J Med Chem | pmid:15642411 |
| Goto M et al. | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. | 2005 | J. Biol. Chem. | pmid:16141215 |
| Homanics GE et al. | Production and characterization of murine models of classic and intermediate maple syrup urine disease. | 2006 | BMC Med. Genet. | pmid:16579849 |
| Portincasa P et al. | Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis. | 2006 | Clin. Sci. | pmid:16603025 |
| Kim J et al. | Characterization of (R)-2-hydroxyisocaproate dehydrogenase and a family III coenzyme A transferase involved in reduction of L-leucine to isocaproate by Clostridium difficile. | 2006 | Appl. Environ. Microbiol. | pmid:16957230 |