4-METHYLPENTANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as CoA-transferase activity. 4-methylpentanoic acid often locates in Cytosol. The related lipids are Fatty Acids and alpha-ketocaproic acid.
To understand associated biological information of 4-METHYLPENTANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 4-METHYLPENTANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Clostridium Infections | D003015 | 5 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Edema | D004487 | 152 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim J et al. | Characterization of (R)-2-hydroxyisocaproate dehydrogenase and a family III coenzyme A transferase involved in reduction of L-leucine to isocaproate by Clostridium difficile. | 2006 | Appl. Environ. Microbiol. | pmid:16957230 |
| Lau NS et al. | Formation of new polyhydroxyalkanoate containing 3-hydroxy-4-methylvalerate monomer in Burkholderia sp. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21279348 |
| Jones SM et al. | Phosphorylation of branched-chain 2-oxo acid dehydrogenase complex in isolated hepatocytes. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3579934 |
| Pizarro-Delgado J et al. | Branched-chain 2-oxoacid transamination increases GABA-shunt metabolism and insulin secretion in isolated islets. | 2009 | Biochem. J. | pmid:19173679 |
| Sener A et al. | Metabolic response to nonglucidic nutrient secretagogues and enzymatic activities in pancreatic islets of adult rats after neonatal streptozotocin administration. | 1993 | Biochem. Med. Metab. Biol. | pmid:8484960 |
| Okada K et al. | Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme. | 2001 | Biochemistry | pmid:11412098 |
| Ledeme N et al. | Purification and enzymatic properties of an L-leucine aminopeptidase from swine liver. | 1981 | Biochim. Biophys. Acta | pmid:7284403 |
| MARTIN WR et al. | beta-Carboxy-beta-hydroxy-isocaproic acid formation by microorganisms. | 1962 | Biochim. Biophys. Acta | pmid:14470457 |
| Tanadchangsaeng N et al. | Identification, biosynthesis, and characterization of polyhydroxyalkanoate copolymer consisting of 3-hydroxybutyrate and 3-hydroxy-4-methylvalerate. | 2009 | Biomacromolecules | pmid:19681605 |
| Tanadchangsaeng N et al. | Comonomer compositional distribution, physical properties, and enzymatic degradability of bacterial poly(3-hydroxybutyrate-co-3-hydroxy-4-methylvalerate) copolyesters. | 2010 | Biomacromolecules | pmid:20441146 |