Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Peutz-Jeghers Syndrome D010580 2 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Celiac Disease D002446 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

Download all related citations
Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Kaneta S et al. All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells. 2003 Atherosclerosis pmid:14612203
Rodríguez JM et al. Fungal metabolic model for 3-methylcrotonyl-CoA carboxylase deficiency. 2004 J. Biol. Chem. pmid:14612443
Dong J et al. Increased expression of plasminogen activator inhibitor-1 by mediators of the acute phase response: a potential progenitor of vasculopathy in hypertensives. 2003 Hypertens. Res. pmid:14620928
pmid:14624137
Huang KC et al. Statins induce suppressor of cytokine signaling-3 in macrophages. 2003 FEBS Lett. pmid:14644448
Stone BG and Evans CD Evidence for a common biliary cholesterol and VLDL cholesterol precursor pool in rat liver. 1992 J. Lipid Res. pmid:1464750
Zacco A et al. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity. 2003 J. Neurosci. pmid:14657168
Rodríguez-Concepción M et al. Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development. 2004 Plant Cell pmid:14660801
Polo MP et al. Effect of ethanol on cell growth and cholesterol metabolism in cultured Hep G2 cells. 2003 Biochem. Cell Biol. pmid:14663504
pmid:14678236
Ruiz-Velasco N et al. Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression. 2004 Biochem. Pharmacol. pmid:14698043
Tringali G et al. Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase. 2004 Neurosci. Lett. pmid:14698450
Peña-Diaz J et al. Mitochondrial localization of the mevalonate pathway enzyme 3-Hydroxy-3-methyl-glutaryl-CoA reductase in the Trypanosomatidae. 2004 Mol. Biol. Cell pmid:14699057
Saijonmaa O et al. Atorvastatin completely inhibits VEGF-induced ACE upregulation in human endothelial cells. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:14704227
Sauane M et al. Leukaemia inhibitory factor or oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication. 2004 Biochem. Biophys. Res. Commun. pmid:14706631
Raupp P et al. Novel genotype of mevalonic aciduria with fatalities in premature siblings. 2004 Arch. Dis. Child. Fetal Neonatal Ed. pmid:14711867
Kasahara H et al. Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. 2004 J. Biol. Chem. pmid:14726522
Pallottini V et al. Age-related changes of isoprenoid biosynthesis in rat liver and brain. 2003 Biogerontology pmid:14739708
Bate C et al. Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. 2004 J. Biol. Chem. pmid:14754889
Turunen M et al. Metabolism and function of coenzyme Q. 2004 Biochim. Biophys. Acta pmid:14757233
Kawasaki T et al. A relationship between the mevalonate pathway and isoprenoid production in actinomycetes. 2003 J. Antibiot. pmid:14763562
Hedl M and Rodwell VW Enterococcus faecalis mevalonate kinase. 2004 Protein Sci. pmid:14767074
Suzuki M et al. Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels. 2004 Plant J. pmid:14871314
Larsson O and Wejde J Dolichol delays G1-arrest for one cell cycle in human fibroblasts subjected to depletion of serum or mevalonate. 1992 J. Cell. Sci. pmid:1487489
Thorpe JL et al. Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. 2004 Dev. Cell pmid:14960282
Thompson K and Rogers MJ Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. 2004 J. Bone Miner. Res. pmid:14969398
pmid:14985071
Fuse M et al. Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways. 2004 Biochem. Biophys. Res. Commun. pmid:14985133
Barkley SJ et al. Identification of an Archaeal type II isopentenyl diphosphate isomerase in methanothermobacter thermautotrophicus. 2004 J. Bacteriol. pmid:14996812
pmid:1499946
Begley M et al. The interplay between classical and alternative isoprenoid biosynthesis controls gammadelta T cell bioactivity of Listeria monocytogenes. 2004 FEBS Lett. pmid:15013758
pmid:15021918
Hedl M et al. Class II 3-hydroxy-3-methylglutaryl coenzyme A reductases. 2004 J. Bacteriol. pmid:15028676
Schulz JG et al. HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis. 2004 J. Neurochem. pmid:15030386
pmid:15034683
pmid:15035434
pmid:15037710
pmid:15038955
Mikulski SM et al. Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. 1992 Br. J. Cancer pmid:1503903
Tokoro T et al. The novel HMG-CoA reductase inhibitor, Pitavastatin, induces a protective action in vascular endothelial cells through the production of nitric oxide (NO). 2004 Yakugaku Zasshi pmid:15049129
Reichart B et al. Expression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutation. 2004 BMC Cell Biol. pmid:15053843
Blanco-Colio LM et al. Decreased circulating Fas ligand in patients with familial combined hyperlipidemia or carotid atherosclerosis: normalization by atorvastatin. 2004 J. Am. Coll. Cardiol. pmid:15063428
Boucher Y et al. Origins and evolution of isoprenoid lipid biosynthesis in archaea. 2004 Mol. Microbiol. pmid:15066037
pmid:15076215
Andela VB Correspondence Re S. S. Virtanen et al., Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway. Cancer Res 2002;62:2708-14. Re K. Sawada et al., Alendronate inhibits lysophosphatidic acid-induced migration of human ovarian cancer cells by attenuating the activation of Rho. Cancer Res 2002;62:6015-20. 2004 Cancer Res. pmid:15087415
Cenedella RJ et al. Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea. 1992 Biochem. Biophys. Res. Commun. pmid:1510688
pmid:15110690
pmid:15116060
Danesh FR and Kanwar YS Modulatory effects of HMG-CoA reductase inhibitors in diabetic microangiopathy. 2004 FASEB J. pmid:15117885
Kuzuyama T et al. Heterologous mevalonate production in Streptomyces lividans TK23. 2004 Biosci. Biotechnol. Biochem. pmid:15118326