Gerber R et al. |
Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS. |
2004 |
Anal. Biochem. |
pmid:15136164
|
Schwartz CC et al. |
Lipoprotein cholesteryl ester production, transfer, and output in vivo in humans. |
2004 |
J. Lipid Res. |
pmid:15145983
|
Hedl M and Rodwell VW |
Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii. |
2004 |
Protein Sci. |
pmid:15152097
|
Duncan RE et al. |
Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclin-dependent kinase-2 activity. |
2004 |
J. Biol. Chem. |
pmid:15155733
|
Rasouli M et al. |
Calmodulin antagonist W-7 inhibits de novo synthesis of cholesterol and suppresses secretion of de novo synthesized and preformed lipids from cultured hepatocytes. |
2004 |
Biochim. Biophys. Acta |
pmid:15158760
|
|
|
|
|
pmid:15169608
|
|
|
|
|
pmid:15171940
|
Dickschat JS et al. |
Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. |
2004 |
Chembiochem |
pmid:15174160
|
Dubuc G et al. |
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15178557
|
Stojanov S et al. |
Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a heterozygous MVK carrier possibly influences the phenotype of hyperimmunoglobulinemia D with periodic fever syndrome or vice versa. |
2004 |
Arthritis Rheum. |
pmid:15188372
|
|
|
|
|
pmid:15197467
|
Ando H et al. |
Effects of pravastatin on the expression of ATP-binding cassette transporter A1. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15210833
|
Le Jossic-Corcos C et al. |
Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes. |
2004 |
Biochim. Biophys. Acta |
pmid:15238219
|
|
|
|
|
pmid:1524429
|
Siddals KW et al. |
Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion: synergy between protein prenylation and receptor glycosylation pathways. |
2004 |
J. Biol. Chem. |
pmid:15247258
|
Harada-Shiba M et al. |
Siblings with normal LDL receptor activity and severe hypercholesterolemia. |
1992 |
Arterioscler. Thromb. |
pmid:1525122
|
Bradfute DL et al. |
Squalene synthase-deficient mutant of Chinese hamster ovary cells. |
1992 |
J. Biol. Chem. |
pmid:1526971
|
|
|
|
|
pmid:15279616
|
Fortin DL et al. |
Lipid rafts mediate the synaptic localization of alpha-synuclein. |
2004 |
J. Neurosci. |
pmid:15282274
|
Sutherlin A and Rodwell VW |
Multienzyme mevalonate pathway bioreactor. |
2004 |
Biotechnol. Bioeng. |
pmid:15286992
|
Werner M et al. |
Mutual amplification of apoptosis by statin-induced mitochondrial stress and doxorubicin toxicity in human rhabdomyosarcoma cells. |
2004 |
Br. J. Pharmacol. |
pmid:15289292
|
Schulz S et al. |
Mechanisms of cell growth inhibition and cell cycle arrest in human colonic adenocarcinoma cells by dehydroepiandrosterone: role of isoprenoid biosynthesis. |
1992 |
Cancer Res. |
pmid:1531325
|
Vaughan CJ and Gotto AM |
Update on statins: 2003. |
2004 |
Circulation |
pmid:15313959
|
del Real G et al. |
Statins inhibit HIV-1 infection by down-regulating Rho activity. |
2004 |
J. Exp. Med. |
pmid:15314078
|
Ikeuchi H et al. |
Fluvastatin reduces renal fibroblast proliferation and production of type III collagen: therapeutic implications for tubulointerstitial fibrosis. |
2004 |
Nephron Exp. Nephrol. |
pmid:15331935
|
|
|
|
|
pmid:15332174
|
Ferrara DE et al. |
Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells. |
2004 |
J. Thromb. Haemost. |
pmid:15333031
|
|
|
|
|
pmid:15352124
|
|
|
|
|
pmid:15355237
|
Zanotti I et al. |
Pitavastatin increases ABCA1-mediated lipid efflux from Fu5AH rat hepatoma cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15358158
|
Bi X et al. |
Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia. |
2004 |
J. Biol. Chem. |
pmid:15364922
|
|
|
|
|
pmid:15370280
|
Sauter GH et al. |
Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects. |
2004 |
Digestion |
pmid:15375335
|
Dahl NK et al. |
Isolation and characterization of Chinese hamster ovary cells defective in the intracellular metabolism of low density lipoprotein-derived cholesterol. |
1992 |
J. Biol. Chem. |
pmid:1537866
|
Umlauf D et al. |
Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae). |
2004 |
Phytochemistry |
pmid:15381410
|
Duncan RE et al. |
Delivery of mevalonate to murine extrahepatic tissues via mini-osmotic pumps. |
2004 Sep-Oct |
J Pharmacol Toxicol Methods |
pmid:15385088
|
Kizu A et al. |
Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators. |
2004 |
J. Cell. Biochem. |
pmid:15389884
|
Seker T et al. |
Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae. |
2005 |
Appl. Microbiol. Biotechnol. |
pmid:15448940
|
Neville-Webbe HL et al. |
Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells. |
2005 |
Int. J. Cancer |
pmid:15455384
|
Sinensky M and Lutz RJ |
The prenylation of proteins. |
1992 |
Bioessays |
pmid:1546978
|
Bhavnani BR and Woolever CA |
Formation of steroids by the pregnant mare. VI. Metabolism of [14C]farnesyl pyrophosphate and [3H]dehydroepiandrosterone injected into the fetus. |
1978 |
Endocrinology |
pmid:155006
|
Fan P et al. |
Pitavastatin, a potent hydroxymethylglutaryl coenzyme a reductase inhibitor, increases cholesterol 7 alpha-hydroxylase gene expression in HepG2 cells. |
2004 |
Circ. J. |
pmid:15502389
|
|
|
|
|
pmid:15503662
|
Anant JS and Fung BK |
In vivo farnesylation of rat rhodopsin kinase. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1550556
|
Giannakouros T et al. |
Protein prenylation in Schizosaccharomyces pombe. |
1992 |
FEBS Lett. |
pmid:1551414
|
Kasim SE et al. |
Mechanisms of triglyceride-lowering effect of an HMG-CoA reductase inhibitor in a hypertriglyceridemic animal model, the Zucker obese rat. |
1992 |
J. Lipid Res. |
pmid:1552226
|
Bell FP et al. |
L-carnitine administration and withdrawal affect plasma and hepatic carnitine concentrations, plasma lipid and lipoprotein composition, and in vitro hepatic lipogenesis from labeled mevalonate and oleate in normal rabbits. |
1992 |
J. Nutr. |
pmid:1552371
|
Friesen JA and Rodwell VW |
The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases. |
2004 |
Genome Biol. |
pmid:15535874
|
|
|
|
|
pmid:15542379
|
|
|
|
|
pmid:15544330
|