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Simvastatin promotes cell metabolism, proliferation, and osteoblastic differentiation in human periodontal ligament cells. |
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HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo. |
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Lupus |
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Fluvastatin prevents vascular hyperplasia by inhibiting phenotype modulation and proliferation through extracellular signal-regulated kinase 1 and 2 and p38 mitogen-activated protein kinase inactivation in organ-cultured artery. |
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The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. |
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Regulation of luteinizing hormone receptor expression: evidence of translational suppression in vitro by a hormonally regulated mRNA-binding protein and its endogenous association with luteinizing hormone receptor mRNA in the ovary. |
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Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. |
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A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. |
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Chembiochem |
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Cyanobacterial non-mevalonate pathway: (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase interacts with ferredoxin in Thermosynechococcus elongatus BP-1. |
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Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor. |
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Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases? |
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Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague-Dawley rats: dose-response, and biochemical and pharamacokinetic parameters. |
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Toxicology |
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Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels. |
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Plant J. |
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Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. |
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Leukaemia inhibitory factor or oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication. |
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Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways. |
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Biochem. Biophys. Res. Commun. |
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Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae). |
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Phytochemistry |
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Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase. |
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Linking lipids, Alzheimer's and LXRs? |
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Nucl Recept Signal |
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A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. |
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Anal. Biochem. |
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Biosynthesis of abscisic acid by the direct pathway via ionylideneethane in a fungus, Cercospora cruenta. |
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Biosci. Biotechnol. Biochem. |
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Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. |
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J. Bone Miner. Res. |
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Protein Sci. |
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Metabolism and function of coenzyme Q. |
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Biochim. Biophys. Acta |
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Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. |
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Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. |
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Dev. Cell |
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