Yang J et al. |
Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. |
2012 |
PLoS ONE |
pmid:22558074
|
Thurnher M et al. |
Novel aspects of mevalonate pathway inhibitors as antitumor agents. |
2012 |
Clin. Cancer Res. |
pmid:22529099
|
Hong SY et al. |
Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. |
2012 |
J. Appl. Microbiol. |
pmid:22519412
|
Iwata A et al. |
Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. |
2012 |
Clin. Exp. Immunol. |
pmid:22471285
|
Luvai A et al. |
Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. |
2012 |
Clin Med Insights Cardiol |
pmid:22442638
|
Lachenmeier DW et al. |
NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements. |
2012 |
Chin Med |
pmid:22439629
|
Keizer HG |
The "Mevalonate hypothesis": a cholesterol-independent alternative for the etiology of atherosclerosis. |
2012 |
Lipids Health Dis |
pmid:23122424
|
Fu X et al. |
Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. |
2012 |
J. Exp. Bot. |
pmid:21994170
|
Zhou K et al. |
Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production. |
2012 |
PLoS ONE |
pmid:23133596
|
Yang D et al. |
Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. |
2012 |
PLoS ONE |
pmid:23209548
|
Iguchi K |
[Effect of bisphosphonates on anticancer activity in prostate cancer cells]. |
2012 |
Yakugaku Zasshi |
pmid:23023419
|
Yokota K et al. |
Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. |
2011 Jan-Feb |
Clin. Exp. Rheumatol. |
pmid:21345291
|
Redding-Johanson AM et al. |
Targeted proteomics for metabolic pathway optimization: application to terpene production. |
2011 |
Metab. Eng. |
pmid:21215324
|
Ma SM et al. |
Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases. |
2011 |
Metab. Eng. |
pmid:21810477
|
Luo H et al. |
Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. |
2011 |
BMC Genomics |
pmid:22369100
|
Youn YN et al. |
Impact of High-Dose Statin Pretreatment in Patients with Stable Angina during Off-Pump Coronary Artery Bypass. |
2011 |
Korean J Thorac Cardiovasc Surg |
pmid:22263153
|
Odom AR |
Five questions about non-mevalonate isoprenoid biosynthesis. |
2011 |
PLoS Pathog. |
pmid:22216001
|
Emma F et al. |
Renal mitochondrial cytopathies. |
2011 |
Int J Nephrol |
pmid:21811680
|
Ageenko NV et al. |
Expression of Pigment Cell-Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius. |
2011 |
Evid Based Complement Alternat Med |
pmid:21804858
|
Cheng G et al. |
Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. |
2011 |
Cancer Biol. Ther. |
pmid:21799303
|
Peng LF et al. |
Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. |
2011 |
J. Infect. Dis. |
pmid:21791663
|
Bajgain P et al. |
Transcriptome characterization and polymorphism detection between subspecies of big sagebrush (Artemisia tridentata). |
2011 |
BMC Genomics |
pmid:21767398
|
Scheller EL et al. |
Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. |
2011 |
J. Cell. Biochem. |
pmid:21751240
|
Brock NL et al. |
Biosynthesis of sesqui- and diterpenes by the gibberellin producer Fusarium fujikuroi. |
2011 |
Chembiochem |
pmid:21990128
|
Henneman L et al. |
Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS. |
2011 |
Biochim. Biophys. Acta |
pmid:21237288
|
Kyathanahalli CN and Kowluru A |
A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGEâ‚‚. |
2011 |
Biochem. Pharmacol. |
pmid:21406184
|
Zhao Y et al. |
Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. |
2011 |
J. Invest. Dermatol. |
pmid:21390048
|
Blankier S et al. |
The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease. |
2011 |
Clin. Exp. Immunol. |
pmid:21361911
|
Ghavami S et al. |
Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. |
2011 |
PLoS ONE |
pmid:21304979
|
Ignea C et al. |
Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. |
2011 |
Microb. Cell Fact. |
pmid:21276210
|
Tuckow AP et al. |
Simvastatin represses protein synthesis in the muscle-derived Câ‚‚Câ‚â‚‚ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression. |
2011 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:21224482
|
Sawai S and Saito K |
Triterpenoid biosynthesis and engineering in plants. |
2011 |
Front Plant Sci |
pmid:22639586
|
Cluis CP et al. |
Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). |
2011 |
Metab. Eng. |
pmid:21986057
|
Relja B et al. |
Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK. |
2011 |
Int. J. Oncol. |
pmid:21206971
|
Kimachi K et al. |
Zoledronic acid inhibits RANK expression and migration of osteoclast precursors during osteoclastogenesis. |
2011 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:21225243
|
Epplen R et al. |
Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. |
2011 |
Acta Oncol |
pmid:20429730
|
Jouneau S et al. |
Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. |
2011 |
PLoS ONE |
pmid:21826199
|
Lin Y et al. |
Triterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters. |
2011 |
Evid Based Complement Alternat Med |
pmid:19228775
|
Zhong WB et al. |
Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. |
2011 |
Biochem. Pharmacol. |
pmid:21907187
|
Zeki AA et al. |
Statin drugs, metabolic pathways, and asthma: a therapeutic opportunity needing further research. |
2011 |
Drug Metab Lett |
pmid:21198438
|
Llacuna L et al. |
Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia-reperfusion injury. |
2011 |
J. Hepatol. |
pmid:21145825
|
Hamada M et al. |
Antithrombotic properties of pravastatin reducing intra-thrombus fibrin deposition under high shear blood flow conditions. |
2011 |
Thromb. Haemost. |
pmid:21136018
|
Hao Q et al. |
Synthesis and anti-hypercholesterolemic evaluations of calcium salts of 4-substituted quinoline-based mevalonic acid. |
2011 |
Chem Biol Drug Des |
pmid:21791012
|
Esemuede N et al. |
Lovastatin inhibits thrombospondin-1-induced smooth muscle cell chemotaxis. |
2011 |
J. Surg. Res. |
pmid:20338582
|
Castella B et al. |
Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. |
2011 |
J. Immunol. |
pmid:21753152
|
Soto G et al. |
Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation. |
2011 |
J. Exp. Bot. |
pmid:21908473
|
Wong DH et al. |
Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells. |
2011 |
Fertil. Steril. |
pmid:21907337
|
Jang HJ et al. |
Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. |
2011 |
Microb. Cell Fact. |
pmid:21801353
|
Leichner GS et al. |
Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. |
2011 |
J. Biol. Chem. |
pmid:21778231
|
Yanae M et al. |
Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. |
2011 |
J. Exp. Clin. Cancer Res. |
pmid:21831290
|