| MeSH term | MeSH ID | Detail |
|---|---|---|
| Peutz-Jeghers Syndrome | D010580 | 2 associated lipids |
| Smith-Lemli-Opitz Syndrome | D019082 | 7 associated lipids |
| Hypergammaglobulinemia | D006942 | 9 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
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All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mokashi V et al. | Supernatant protein factor stimulates HMG-CoA reductase in cell culture and in vitro. | 2005 | Arch. Biochem. Biophys. | pmid:15581604 |
| Yazawa H et al. | Simvastatin promotes cell metabolism, proliferation, and osteoblastic differentiation in human periodontal ligament cells. | 2005 | J. Periodontol. | pmid:15974856 |
| Han KH et al. | HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo. | 2005 | Circulation | pmid:15781755 |
| Hampel D et al. | Induction of de novo volatile terpene biosynthesis via cytosolic and plastidial pathways by methyl jasmonate in foliage of Vitis vinifera L. | 2005 | J. Agric. Food Chem. | pmid:15796607 |
| Argmann CA et al. | Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. | 2005 | J. Biol. Chem. | pmid:15817453 |
| Murthy S et al. | Regulation of fatty acid synthesis by farnesyl pyrophosphate. | 2005 | J. Biol. Chem. | pmid:16221687 |
| Ota K et al. | Effect of pitavastatin on transactivation of human serum paraoxonase 1 gene. | 2005 | Metab. Clin. Exp. | pmid:15690306 |
| Bevilacqua M et al. | Bisphosphonates and atherosclerosis: why? | 2005 | Lupus | pmid:16218486 |
| Sakamoto K et al. | Fluvastatin prevents vascular hyperplasia by inhibiting phenotype modulation and proliferation through extracellular signal-regulated kinase 1 and 2 and p38 mitogen-activated protein kinase inactivation in organ-cultured artery. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15591221 |
| Kim J et al. | 4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway. | 2005 | J. Chem. Ecol. | pmid:16222778 |
| Baker SK | Molecular clues into the pathogenesis of statin-mediated muscle toxicity. | 2005 | Muscle Nerve | pmid:15712281 |
| Neville-Webbe HL et al. | Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells. | 2005 | Int. J. Cancer | pmid:15455384 |
| Enfissi EM et al. | Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato. | 2005 | Plant Biotechnol. J. | pmid:17168896 |
| Dudareva N et al. | The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15630092 |
| Duncan RE et al. | Dietary factors and the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for breast cancer and development. | 2005 | Mol Nutr Food Res | pmid:15617098 |
| Nair AK and Menon KM | Regulation of luteinizing hormone receptor expression: evidence of translational suppression in vitro by a hormonally regulated mRNA-binding protein and its endogenous association with luteinizing hormone receptor mRNA in the ovary. | 2005 | J. Biol. Chem. | pmid:16263716 |
| Duncan RE et al. | Statins and cancer development. | 2005 | Cancer Epidemiol. Biomarkers Prev. | pmid:16103434 |
| Girlanda S et al. | MICA expressed by multiple myeloma and monoclonal gammopathy of undetermined significance plasma cells Costimulates pamidronate-activated gammadelta lymphocytes. | 2005 | Cancer Res. | pmid:16103105 |
| Tucker DE et al. | Group IVC cytosolic phospholipase A2gamma is farnesylated and palmitoylated in mammalian cells. | 2005 | J. Lipid Res. | pmid:16061942 |
| Bocci G et al. | Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells. | 2005 | Br. J. Cancer | pmid:16052215 |
| Luckman SP et al. | JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998). | 2005 | J. Bone Miner. Res. | pmid:16050006 |
| Saiki A et al. | Pitavastatin enhanced lipoprotein lipase expression in 3T3-L1 preadipocytes. | 2005 | J. Atheroscler. Thromb. | pmid:16020917 |
| Wei H et al. | Statin-inhibited endothelial permeability could be associated with its effect on PECAM-1 in endothelial cells. | 2005 | FEBS Lett. | pmid:15710425 |
| Paradisi M et al. | Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress. | 2005 | BMC Cell Biol. | pmid:15982412 |
| Viereck V et al. | Atorvastatin stimulates the production of osteoprotegerin by human osteoblasts. | 2005 | J. Cell. Biochem. | pmid:16152630 |
| Sacher J et al. | Delineation of myotoxicity induced by 3-hydroxy-3-methylglutaryl CoA reductase inhibitors in human skeletal muscle cells. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15914674 |
| Wang C et al. | Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. | 2005 | Mol. Cell | pmid:15893726 |
| Mahmud T et al. | A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. | 2005 | Chembiochem | pmid:15619721 |
| Okada K and Hase T | Cyanobacterial non-mevalonate pathway: (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase interacts with ferredoxin in Thermosynechococcus elongatus BP-1. | 2005 | J. Biol. Chem. | pmid:15792953 |
| Mantha AJ et al. | Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor. | 2005 | Clin. Cancer Res. | pmid:15788691 |
| McCarey DW et al. | Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases? | 2005 | Arthritis Res. Ther. | pmid:15743490 |
| Zeng L et al. | HMG CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation. | 2005 | FASEB J. | pmid:16160062 |
| Luebker DJ et al. | Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague-Dawley rats: dose-response, and biochemical and pharamacokinetic parameters. | 2005 | Toxicology | pmid:16129535 |
| Duncan RE et al. | Delivery of mevalonate to murine extrahepatic tissues via mini-osmotic pumps. | 2004 Sep-Oct | J Pharmacol Toxicol Methods | pmid:15385088 |
| Ruiz-Velasco N et al. | Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression. | 2004 | Biochem. Pharmacol. | pmid:14698043 |
| Schulz JG et al. | HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis. | 2004 | J. Neurochem. | pmid:15030386 |
| Danesh FR and Kanwar YS | Modulatory effects of HMG-CoA reductase inhibitors in diabetic microangiopathy. | 2004 | FASEB J. | pmid:15117885 |
| Kizu A et al. | Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators. | 2004 | J. Cell. Biochem. | pmid:15389884 |
| Suzuki M et al. | Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels. | 2004 | Plant J. | pmid:14871314 |
| Dubuc G et al. | Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:15178557 |
| Rasouli M et al. | Calmodulin antagonist W-7 inhibits de novo synthesis of cholesterol and suppresses secretion of de novo synthesized and preformed lipids from cultured hepatocytes. | 2004 | Biochim. Biophys. Acta | pmid:15158760 |
| Gerber R et al. | Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS. | 2004 | Anal. Biochem. | pmid:15136164 |
| Bi X et al. | Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia. | 2004 | J. Biol. Chem. | pmid:15364922 |
| del Real G et al. | Statins inhibit HIV-1 infection by down-regulating Rho activity. | 2004 | J. Exp. Med. | pmid:15314078 |
| Peña-Diaz J et al. | Mitochondrial localization of the mevalonate pathway enzyme 3-Hydroxy-3-methyl-glutaryl-CoA reductase in the Trypanosomatidae. | 2004 | Mol. Biol. Cell | pmid:14699057 |
| RodrÃguez JM et al. | Fungal metabolic model for 3-methylcrotonyl-CoA carboxylase deficiency. | 2004 | J. Biol. Chem. | pmid:14612443 |
| Bate C et al. | Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. | 2004 | J. Biol. Chem. | pmid:14754889 |
| Sauane M et al. | Leukaemia inhibitory factor or oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication. | 2004 | Biochem. Biophys. Res. Commun. | pmid:14706631 |
| Panda T and Devi VA | Regulation and degradation of HMGCo-A reductase. | 2004 | Appl. Microbiol. Biotechnol. | pmid:15558272 |
| Fuse M et al. | Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways. | 2004 | Biochem. Biophys. Res. Commun. | pmid:14985133 |
| Tabata K and Hashimoto S | Production of mevalonate by a metabolically-engineered Escherichia coli. | 2004 | Biotechnol. Lett. | pmid:15604784 |
| Zanotti I et al. | Pitavastatin increases ABCA1-mediated lipid efflux from Fu5AH rat hepatoma cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15358158 |
| Sutherlin A and Rodwell VW | Multienzyme mevalonate pathway bioreactor. | 2004 | Biotechnol. Bioeng. | pmid:15286992 |
| Schwartz CC et al. | Lipoprotein cholesteryl ester production, transfer, and output in vivo in humans. | 2004 | J. Lipid Res. | pmid:15145983 |
| Dickschat JS et al. | Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. | 2004 | Chembiochem | pmid:15174160 |
| Ikeuchi H et al. | Fluvastatin reduces renal fibroblast proliferation and production of type III collagen: therapeutic implications for tubulointerstitial fibrosis. | 2004 | Nephron Exp. Nephrol. | pmid:15331935 |
| Saijonmaa O et al. | Atorvastatin completely inhibits VEGF-induced ACE upregulation in human endothelial cells. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:14704227 |
| Umlauf D et al. | Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae). | 2004 | Phytochemistry | pmid:15381410 |
| Tringali G et al. | Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase. | 2004 | Neurosci. Lett. | pmid:14698450 |
| Bellosta S et al. | Statins effect on smooth muscle cell proliferation. | 2004 | Semin Vasc Med | pmid:15861311 |
| Hedl M et al. | Class II 3-hydroxy-3-methylglutaryl coenzyme A reductases. | 2004 | J. Bacteriol. | pmid:15028676 |
| Barkley SJ et al. | Identification of an Archaeal type II isopentenyl diphosphate isomerase in methanothermobacter thermautotrophicus. | 2004 | J. Bacteriol. | pmid:14996812 |
| Patel NV and Forman BM | Linking lipids, Alzheimer's and LXRs? | 2004 | Nucl Recept Signal | pmid:16604185 |
| Raschke M et al. | A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. | 2004 | Anal. Biochem. | pmid:15556562 |
| Tokoro T et al. | The novel HMG-CoA reductase inhibitor, Pitavastatin, induces a protective action in vascular endothelial cells through the production of nitric oxide (NO). | 2004 | Yakugaku Zasshi | pmid:15049129 |
| Kawasaki T et al. | Presence of copalyl diphosphate synthase gene in an actinomycete possessing the mevalonate pathway. | 2004 | J. Antibiot. | pmid:15712669 |
| Inomata M et al. | Biosynthesis of abscisic acid by the direct pathway via ionylideneethane in a fungus, Cercospora cruenta. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15618629 |
| Friesen JA and Rodwell VW | The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases. | 2004 | Genome Biol. | pmid:15535874 |
| Sauter GH et al. | Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects. | 2004 | Digestion | pmid:15375335 |
| Fan P et al. | Pitavastatin, a potent hydroxymethylglutaryl coenzyme a reductase inhibitor, increases cholesterol 7 alpha-hydroxylase gene expression in HepG2 cells. | 2004 | Circ. J. | pmid:15502389 |
| Ferrara DE et al. | Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells. | 2004 | J. Thromb. Haemost. | pmid:15333031 |
| Vaughan CJ and Gotto AM | Update on statins: 2003. | 2004 | Circulation | pmid:15313959 |
| Werner M et al. | Mutual amplification of apoptosis by statin-induced mitochondrial stress and doxorubicin toxicity in human rhabdomyosarcoma cells. | 2004 | Br. J. Pharmacol. | pmid:15289292 |
| Siddals KW et al. | Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion: synergy between protein prenylation and receptor glycosylation pathways. | 2004 | J. Biol. Chem. | pmid:15247258 |
| Ando H et al. | Effects of pravastatin on the expression of ATP-binding cassette transporter A1. | 2004 | J. Pharmacol. Exp. Ther. | pmid:15210833 |
| Stojanov S et al. | Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a heterozygous MVK carrier possibly influences the phenotype of hyperimmunoglobulinemia D with periodic fever syndrome or vice versa. | 2004 | Arthritis Rheum. | pmid:15188372 |
| Duncan RE et al. | Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclin-dependent kinase-2 activity. | 2004 | J. Biol. Chem. | pmid:15155733 |
| Hedl M and Rodwell VW | Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii. | 2004 | Protein Sci. | pmid:15152097 |
| Kuzuyama T et al. | Heterologous mevalonate production in Streptomyces lividans TK23. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15118326 |
| Andreassi JL et al. | Streptococcus pneumoniae isoprenoid biosynthesis is downregulated by diphosphomevalonate: an antimicrobial target. | 2004 | Biochemistry | pmid:15610040 |
| Andela VB | Correspondence Re S. S. Virtanen et al., Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway. Cancer Res 2002;62:2708-14. Re K. Sawada et al., Alendronate inhibits lysophosphatidic acid-induced migration of human ovarian cancer cells by attenuating the activation of Rho. Cancer Res 2002;62:6015-20. | 2004 | Cancer Res. | pmid:15087415 |
| Boucher Y et al. | Origins and evolution of isoprenoid lipid biosynthesis in archaea. | 2004 | Mol. Microbiol. | pmid:15066037 |
| Blanco-Colio LM et al. | Decreased circulating Fas ligand in patients with familial combined hyperlipidemia or carotid atherosclerosis: normalization by atorvastatin. | 2004 | J. Am. Coll. Cardiol. | pmid:15063428 |
| Reichart B et al. | Expression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutation. | 2004 | BMC Cell Biol. | pmid:15053843 |
| Begley M et al. | The interplay between classical and alternative isoprenoid biosynthesis controls gammadelta T cell bioactivity of Listeria monocytogenes. | 2004 | FEBS Lett. | pmid:15013758 |
| Thompson K and Rogers MJ | Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. | 2004 | J. Bone Miner. Res. | pmid:14969398 |
| Hedl M and Rodwell VW | Enterococcus faecalis mevalonate kinase. | 2004 | Protein Sci. | pmid:14767074 |
| Turunen M et al. | Metabolism and function of coenzyme Q. | 2004 | Biochim. Biophys. Acta | pmid:14757233 |
| Kasahara H et al. | Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. | 2004 | J. Biol. Chem. | pmid:14726522 |
| Raupp P et al. | Novel genotype of mevalonic aciduria with fatalities in premature siblings. | 2004 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:14711867 |
| RodrÃguez-Concepción M et al. | Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development. | 2004 | Plant Cell | pmid:14660801 |
| Le Jossic-Corcos C et al. | Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes. | 2004 | Biochim. Biophys. Acta | pmid:15238219 |
| Fortin DL et al. | Lipid rafts mediate the synaptic localization of alpha-synuclein. | 2004 | J. Neurosci. | pmid:15282274 |
| Thorpe JL et al. | Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. | 2004 | Dev. Cell | pmid:14960282 |
| Hong SB et al. | Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots. | 2003 May-Jun | Biotechnol. Prog. | pmid:12790690 |
| Shimada Y et al. | Organ-specific expression of brassinosteroid-biosynthetic genes and distribution of endogenous brassinosteroids in Arabidopsis. | 2003 | Plant Physiol. | pmid:12529536 |
| Pallottini V et al. | Age-related changes of isoprenoid biosynthesis in rat liver and brain. | 2003 | Biogerontology | pmid:14739708 |
| Houten SM et al. | Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation. | 2003 | Cell. Mol. Life Sci. | pmid:12861380 |
| Kawasaki T et al. | A relationship between the mevalonate pathway and isoprenoid production in actinomycetes. | 2003 | J. Antibiot. | pmid:14763562 |
| Sever N et al. | Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain. | 2003 | Mol. Cell | pmid:12535518 |