Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Peutz-Jeghers Syndrome D010580 2 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Celiac Disease D002446 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Authors Title Published Journal PubMed Link
Björkhem-Bergman L et al. Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. 2010 Anticancer Res. pmid:20530415
Morrone D et al. Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. 2010 Appl. Microbiol. Biotechnol. pmid:19777230
Wang C et al. Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. 2010 Biotechnol. Bioeng. pmid:20552672
Fukunaga M et al. Mast cell death induced by 24(S),25-epoxycholesterol. 2010 Exp. Cell Res. pmid:20854813
Bouvier-Navé P et al. Involvement of the phospholipid sterol acyltransferase1 in plant sterol homeostasis and leaf senescence. 2010 Plant Physiol. pmid:19923239
Jarrell KF et al. S-layer glycoproteins and flagellins: reporters of archaeal posttranslational modifications. 2010 Archaea pmid:20721273
Yang L et al. [Effects of clinically effective dose of lovastatin on prostate cancer PC3 cells]. 2010 Beijing Da Xue Xue Bao pmid:20721249
Guella G et al. Structures, biological activities and phylogenetic relationships of terpenoids from marine ciliates of the genus Euplotes. 2010 Mar Drugs pmid:20714425
Jana S and Shekhawat GS Anethum graveolens: An Indian traditional medicinal herb and spice. 2010 Pharmacogn Rev pmid:22228959
Zheng Z et al. Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome proliferator-activated receptor gamma coactivator 1alpha. 2010 Diabetes pmid:20566666
Liu Q et al. Dynamics of lamin-A processing following precursor accumulation. 2010 PLoS ONE pmid:20526372
Aoyama T et al. Pharmacokinetic/pharmacodynamic modeling and simulation of rosuvastatin using an extension of the indirect response model by incorporating a circadian rhythm. 2010 Biol. Pharm. Bull. pmid:20522984
Jameson JM et al. A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes. 2010 Cell. Immunol. pmid:20483407
Hughes M et al. Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP. 2010 J. Neurochem. pmid:20477946
Targett-Adams P et al. Lipid metabolism and HCV infection. 2010 Viruses pmid:21994676
Palozza P et al. Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines. 2010 Carcinogenesis pmid:20699249
Domoki F et al. Rosuvastatin induces delayed preconditioning against L-glutamate excitotoxicity in cultured cortical neurons. 2010 Neurochem. Int. pmid:19931334
Tisch D and Schmoll M Light regulation of metabolic pathways in fungi. 2010 Appl. Microbiol. Biotechnol. pmid:19915832
Acquavella N et al. Effect of simvastatin on endothelial cell apoptosis mediated by Fas and TNF-alpha. 2010 Cytokine pmid:19932975
Coscia M et al. Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. 2010 J. Cell. Mol. Med. pmid:19818098
Massaro M et al. Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability. 2010 Cardiovasc. Res. pmid:19946014
Liu YJ et al. Simvastatin ameliorates rat cerebrovascular remodeling during hypertension via inhibition of volume-regulated chloride channel. 2010 Hypertension pmid:20644009
Räikkönen J et al. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. 2010 Biochem. Pharmacol. pmid:19819230
Mitrofan LM et al. Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. 2010 J. Biol. Chem. pmid:19875454
Rossi J et al. Laminar shear stress prevents simvastatin-induced adhesion molecule expression in cytokine activated endothelial cells. 2010 Eur. J. Pharmacol. pmid:20863785
Kaneda T et al. Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells. 2010 Eur. J. Pharmacol. pmid:20851116
Barter MJ et al. Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation. 2010 Ann. Rheum. Dis. pmid:20693272
Tsuchiya M et al. Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta-cells. 2010 Endocrinology pmid:20685866
Kocsis GF et al. Expression of genes related to oxidative/nitrosative stress in mouse hearts: effect of preconditioning and cholesterol diet. 2010 Med. Sci. Monit. pmid:20037483
Endo A A historical perspective on the discovery of statins. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20467214
Tekpli X et al. Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis. 2010 Toxicol. Appl. Pharmacol. pmid:19931295
Clendening JW et al. Dysregulation of the mevalonate pathway promotes transformation. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20696928
Rico J et al. Enhanced production of a plant monoterpene by overexpression of the 3-hydroxy-3-methylglutaryl coenzyme A reductase catalytic domain in Saccharomyces cerevisiae. 2010 Appl. Environ. Microbiol. pmid:20675444
Okamura E et al. Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20534558
Chen CC et al. Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43. 2010 J. Appl. Physiol. pmid:20466804
Norman KL and Sarnow P Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms. 2010 J. Virol. pmid:19846523
Schramek N et al. Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study. 2010 Phytochemistry pmid:19932496
Huang M et al. Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. 2010 Plant Physiol. pmid:20463089
Yoon HE and Yang CW Established and newly proposed mechanisms of chronic cyclosporine nephropathy. 2009 Korean J. Intern. Med. pmid:19543484
Jauhiainen M et al. Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19665949
Anthony JR et al. Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene. 2009 Metab. Eng. pmid:18775787
de Souza W and Rodrigues JC Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. 2009 Interdiscip Perspect Infect Dis pmid:19680554
Zeki AA et al. Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond. 2009 Am. J. Respir. Crit. Care Med. pmid:19608720
Minichsdorfer C and Hohenegger M Autocrine amplification loop in statin-induced apoptosis of human melanoma cells. 2009 Br. J. Pharmacol. pmid:19563533
Perttilä J et al. OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. 2009 J. Mol. Med. pmid:19554302
Alvarez Y et al. Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin. 2009 J. Pharmacol. Exp. Ther. pmid:19318593
Niessen J et al. Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin. 2009 Drug Metab. Dispos. pmid:19237515
Yeger-Lotem E et al. Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity. 2009 Nat. Genet. pmid:19234470
Dueber JE et al. Synthetic protein scaffolds provide modular control over metabolic flux. 2009 Nat. Biotechnol. pmid:19648908
Alagna F et al. Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. 2009 BMC Genomics pmid:19709400