| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alonso-Gutierrez J et al. | Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production. | 2013 | Metab. Eng. | pmid:23727191 |
| Theesfeld CL and Hampton RY | Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast. | 2013 | J. Biol. Chem. | pmid:23306196 |
| van der Burgh R et al. | Mevalonate kinase deficiency, a metabolic autoinflammatory disease. | 2013 | Clin. Immunol. | pmid:23110805 |
| Hosaka A et al. | Statins reduce amyloid β-peptide production by modulating amyloid precursor protein maturation and phosphorylation through a cholesterol-independent mechanism in cultured neurons. | 2013 | Neurochem. Res. | pmid:23269484 |
| Qi XF et al. | HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway. | 2013 | Cell Death Dis | pmid:23449454 |
| Tricarico PM et al. | Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study. | 2013 | Biomed Res Int | pmid:24073415 |
| Tyurin M | Gene replacement and elimination using λRed- and FLP-based tool to re-direct carbon flux in acetogen biocatalyst during continuous CO₂/H₂ blend fermentation. | 2013 | J. Ind. Microbiol. Biotechnol. | pmid:23649912 |
| MartÃn-Navarro CM et al. | Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections. | 2013 | Antimicrob. Agents Chemother. | pmid:23114753 |
| Zhang J et al. | Statins directly suppress cytokine production in murine intraepithelial lymphocytes. | 2013 | Cytokine | pmid:23290865 |
| Rauthan M et al. | The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23530189 |
| Blanc M et al. | The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. | 2013 | Immunity | pmid:23273843 |
| Wang C et al. | Engineered heterologous FPP synthases-mediated Z,E-FPP synthesis in E. coli. | 2013 | Metab. Eng. | pmid:23608473 |
| Yu W et al. | The mevalonate auxotrophic mutant of Staphylococcus aureus can adapt to mevalonate depletion. | 2013 | Antimicrob. Agents Chemother. | pmid:23959312 |
| Szűcs G et al. | Cardioprotection by farnesol: role of the mevalonate pathway. | 2013 | Cardiovasc Drugs Ther | pmid:23673412 |
| Ramak P et al. | Inhibition of the mevalonate pathway enhances carvacrol biosynthesis and DXR gene expression in shoot cultures of Satureja khuzistanica Jamzad. | 2013 | J. Plant Physiol. | pmid:23611428 |
| Chen X et al. | Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. | 2013 | PLoS ONE | pmid:24278153 |
| Chang WC et al. | Current development in isoprenoid precursor biosynthesis and regulation. | 2013 | Curr Opin Chem Biol | pmid:23891475 |
| Tuerdi G et al. | Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells. | 2013 | Cancer Lett. | pmid:23879968 |
| Gopalan A et al. | Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway. | 2013 | Cancer Lett. | pmid:22960596 |
| Onono F et al. | Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. | 2013 | J. Biol. Chem. | pmid:23908355 |
| Gopalan A et al. | Eliminating drug resistant breast cancer stem-like cells with combination of simvastatin and gamma-tocotrienol. | 2013 | Cancer Lett. | pmid:23063651 |
| Liu J et al. | Overproduction of geraniol by enhanced precursor supply in Saccharomyces cerevisiae. | 2013 | J. Biotechnol. | pmid:24161921 |
| Lee SK and Kim YS | Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria. | 2013 | Int. J. Oncol. | pmid:23354132 |
| Valente AJ et al. | Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin. | 2013 | Cell. Signal. | pmid:23541442 |
| Xiao H et al. | Inhibition of Rho and Rac geranylgeranylation by atorvastatin is critical for preservation of endothelial junction integrity. | 2013 | PLoS ONE | pmid:23555637 |
| Villanueva JA et al. | Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells. | 2013 | J. Clin. Endocrinol. Metab. | pmid:23386644 |
| May B et al. | Biosynthesis of sesquiterpenes in grape berry exocarp of Vitis vinifera L.: evidence for a transport of farnesyl diphosphate precursors from plastids to the cytosol. | 2013 | Phytochemistry | pmid:23954075 |
| Chen B et al. | Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction. | 2013 | Cell. Physiol. Biochem. | pmid:24356578 |
| Dellas N et al. | Discovery of a metabolic alternative to the classical mevalonate pathway. | 2013 | Elife | pmid:24327557 |
| Bruzzese F et al. | Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways. | 2013 | Cell Death Dis | pmid:24157872 |
| Dick M et al. | Statin therapy influences endothelial cell morphology and F-actin cytoskeleton structure when exposed to static and laminar shear stress conditions. | 2013 | Life Sci. | pmid:23517776 |
| Fang SY et al. | Pleiotropic vascular protective effects of statins in perioperative medicine. | 2013 | Acta Anaesthesiol Taiwan | pmid:24148741 |
| Maciejak A et al. | The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase. | 2013 | BMC Biotechnol. | pmid:24128347 |
| Polidoro S et al. | Effects of bisphosphonate treatment on DNA methylation in osteonecrosis of the jaw. | 2013 | Mutat. Res. | pmid:23892139 |
| Ohukainen P | If the wheel ain't broke, don't reinvent it. | 2013 | Lipids Health Dis | pmid:23577775 |
| Werner M et al. | Simvastatin-induced compartmentalisation of doxorubicin sharpens up nuclear topoisomerase II inhibition in human rhabdomyosarcoma cells. | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23564041 |
| Zhu Y et al. | Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases. | 2013 | Cell Death Dis | pmid:23559002 |
| Lee NY and Kang YS | The effects of bisphosphonates on taurine transport in retinal capillary endothelial cells under high glucose conditions. | 2013 | Adv. Exp. Med. Biol. | pmid:23392871 |
| Corcos L and Le Jossic-Corcos C | Statins: perspectives in cancer therapeutics. | 2013 | Dig Liver Dis | pmid:23490341 |
| Lesma E et al. | Chromatin remodeling by rosuvastatin normalizes TSC2-/meth cell phenotype through the expression of tuberin. | 2013 | J. Pharmacol. Exp. Ther. | pmid:23426956 |
| Doblas VG et al. | The SUD1 gene encodes a putative E3 ubiquitin ligase and is a positive regulator of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in Arabidopsis. | 2013 | Plant Cell | pmid:23404890 |
| Lazzerini PE et al. | Rosuvastatin inhibits spontaneous and IL-1β-induced interleukin-6 production from human cultured osteoblastic cells. | 2013 | Joint Bone Spine | pmid:22999910 |
| Mazein A et al. | A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway. | 2013 | Biochem. Pharmacol. | pmid:23583456 |
| Angaman DM et al. | Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. | 2012 | Plant Methods | pmid:22243738 |
| Yano K | Lipid metabolic pathways as lung cancer therapeutic targets: a computational study. | 2012 | Int. J. Mol. Med. | pmid:22211244 |
| Guo H et al. | Rosuvastatin may modulate insulin signaling and inhibit atherogenesis beyond its plasma cholesterol-lowering effect in insulin-resistant mice. | 2012 | Cardiovasc Drugs Ther | pmid:22918601 |
| Wu S et al. | Engineering triterpene metabolism in tobacco. | 2012 | Planta | pmid:22729821 |
| Ginestier C et al. | p53 and cancer stem cells: the mevalonate connexion. | 2012 | Cell Cycle | pmid:22751434 |
| Zhang B et al. | Interference in mevalonate pathway ameliorates homocysteine-induced endothelium-dysfunction. | 2012 | Eur. J. Pharmacol. | pmid:22796672 |
| Barta ML et al. | Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. | 2012 | Biochemistry | pmid:22734632 |