Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Leukemia D007938 74 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Huang SH et al. Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin. 2011 PLoS ONE pmid:21966365
Yu F et al. Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. 2011 Cell. Mol. Life Sci. pmid:20730551
Nes WD Biosynthesis of cholesterol and other sterols. 2011 Chem. Rev. pmid:21902244
Bergman P et al. Studies on the antibacterial effects of statins--in vitro and in vivo. 2011 PLoS ONE pmid:21912631
Sakamoto K et al. Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes. 2011 BMC Musculoskelet Disord pmid:21524281
Han J et al. Alteration of enzyme expressions in mevalonate pathway: possible role for cardiovascular remodeling in spontaneously hypertensive rats. 2011 Circ. J. pmid:21467659
Siddals KW et al. Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization. 2011 J. Biol. Chem. pmid:21454560
Mongélard G et al. Measurement of carbon flux through the MEP pathway for isoprenoid synthesis by (31)P-NMR spectroscopy after specific inhibition of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate reductase. Effect of light and temperature. 2011 Plant Cell Environ. pmid:21443577
Schaafsma D et al. Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. 2011 Respir. Res. pmid:21864337
Simkin AJ et al. Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta. 2011 Planta pmid:21655959
Maki KC et al. Effects of soy protein on lipoprotein lipids and fecal bile acid excretion in men and women with moderate hypercholesterolemia. 2010 Nov-Dec J Clin Lipidol pmid:21122701
Camps D [Controversies regarding the use of statins in the acute coronary syndrome]. 2010 Aug-Sep Med Intensiva pmid:20538377
Omar SH Oleuropein in olive and its pharmacological effects. 2010 Apr-Jun Sci Pharm pmid:21179340
Wani TA et al. The effects of rosuvastatin on the serum cortisol, serum lipid, and serum mevalonic acid levels in the healthy Indian male population. 2010 AAPS PharmSciTech pmid:20300897
Björkhem-Bergman L et al. Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. 2010 Anticancer Res. pmid:20530415
Morrone D et al. Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. 2010 Appl. Microbiol. Biotechnol. pmid:19777230
Wang C et al. Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. 2010 Biotechnol. Bioeng. pmid:20552672
Honour JW Steroid assays in paediatric endocrinology. 2010 J Clin Res Pediatr Endocrinol pmid:21274330
Head BP et al. Loss of caveolin-1 accelerates neurodegeneration and aging. 2010 PLoS ONE pmid:21203469
Liu Q et al. Dynamics of lamin-A processing following precursor accumulation. 2010 PLoS ONE pmid:20526372
Aoyama T et al. Pharmacokinetic/pharmacodynamic modeling and simulation of rosuvastatin using an extension of the indirect response model by incorporating a circadian rhythm. 2010 Biol. Pharm. Bull. pmid:20522984
Jameson JM et al. A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes. 2010 Cell. Immunol. pmid:20483407
Hughes M et al. Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP. 2010 J. Neurochem. pmid:20477946
Targett-Adams P et al. Lipid metabolism and HCV infection. 2010 Viruses pmid:21994676
Snoeren TA et al. The herbivore-induced plant volatile methyl salicylate negatively affects attraction of the parasitoid Diadegma semiclausum. 2010 J. Chem. Ecol. pmid:20407809
Lefurgy ST et al. Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae. 2010 J. Biol. Chem. pmid:20404339
Palozza P et al. Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines. 2010 Carcinogenesis pmid:20699249
Clendening JW et al. Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma. 2010 Blood pmid:20360469
Delang L et al. Antiviral therapy for hepatitis C virus: beyond the standard of care. 2010 Viruses pmid:21994657
Yang Z et al. Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. 2010 Int. J. Cancer pmid:19626588
Tisch D and Schmoll M Light regulation of metabolic pathways in fungi. 2010 Appl. Microbiol. Biotechnol. pmid:19915832
Acquavella N et al. Effect of simvastatin on endothelial cell apoptosis mediated by Fas and TNF-alpha. 2010 Cytokine pmid:19932975
Coscia M et al. Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. 2010 J. Cell. Mol. Med. pmid:19818098
Kones R Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. 2010 Drug Des Devel Ther pmid:21267417
Hooff GP et al. Isoprenoids, small GTPases and Alzheimer's disease. 2010 Biochim. Biophys. Acta pmid:20382260
Räikkönen J et al. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. 2010 Biochem. Pharmacol. pmid:19819230
Mitrofan LM et al. Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. 2010 J. Biol. Chem. pmid:19875454
Barter MJ et al. Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation. 2010 Ann. Rheum. Dis. pmid:20693272
Tsuchiya M et al. Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta-cells. 2010 Endocrinology pmid:20685866
Quist-Paulsen P Statins and inflammation: an update. 2010 Curr. Opin. Cardiol. pmid:20421792
Endo A A historical perspective on the discovery of statins. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20467214
Tekpli X et al. Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis. 2010 Toxicol. Appl. Pharmacol. pmid:19931295
Rico J et al. Enhanced production of a plant monoterpene by overexpression of the 3-hydroxy-3-methylglutaryl coenzyme A reductase catalytic domain in Saccharomyces cerevisiae. 2010 Appl. Environ. Microbiol. pmid:20675444
Okamura E et al. Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20534558
Chen CC et al. Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43. 2010 J. Appl. Physiol. pmid:20466804
Norman KL and Sarnow P Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms. 2010 J. Virol. pmid:19846523
Jiang XS et al. Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency. 2010 Mol. Cell Proteomics pmid:20305089
Schramek N et al. Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study. 2010 Phytochemistry pmid:19932496
Huang M et al. Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. 2010 Plant Physiol. pmid:20463089
Weerasinghe S and Samantha Dassanayake R Simulation of structural and functional properties of mevalonate diphosphate decarboxylase (MVD). 2010 J Mol Model pmid:19653015