| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Glioma | D005910 | 112 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hu ZY et al. | Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3479785 |
| Forman BM et al. | The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9380679 |
| Pronin AN and Gautam N | Interaction between G-protein beta and gamma subunit types is selective. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631113 |
| Liu GC et al. | Measurement of cholesterol synthesis in man by isotope kinetics of squalene. | 1975 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1060141 |
| Epstein WW et al. | Quantitation of prenylcysteines by a selective cleavage reaction. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1946384 |
| Shi Z and Ruvkun G | The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22396595 |
| Jakóbisiak M et al. | Cell cycle-specific effects of lovastatin. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1673788 |
| Jackson JH et al. | Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2183224 |
| Parker TS et al. | Mevalonic acid in human plasma: relationship of concentration and circadian rhythm to cholesterol synthesis rates in man. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953446 |
| Lange BM and Croteau R | Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570138 |
| Saito Y et al. | Animal cell mutants defective in sterol metabolism: a specific selection procedure and partial characterization of defects. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:269426 |
| Rauthan M et al. | The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23530189 |
| Cuthbert JA and Lipsky PE | Modulation of human lymphocyte responses by low density lipoproteins (LDL): enhancement but not immunosuppression is mediated by LDL receptors. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6087331 |
| Tianero MD et al. | Metabolic model for diversity-generating biosynthesis. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26831074 |
| Yasmin S et al. | Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22106303 |
| Larson RA et al. | Neutrophils are required for the DNA synthetic response of human lymphocytes to mevalonic acid: evidence suggesting that a nonsterol product of mevalonate is involved. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953445 |
| Huneeus VQ et al. | Isopentenyladenine as a mediator of mevalonate-regulated DNA replication. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6934516 |
| Kopito RR and Brunengraber H | (R)-mevalonate excretion in human and rat urines. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6255462 |
| Brown MS and Goldstein JL | Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. | 1974 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4362634 |
| Autefage H et al. | Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25831522 |
| Polotskaia A et al. | Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25733866 |
| Fisher JE et al. | Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874784 |
| Giron MD et al. | Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8022795 |
| Sinensky M et al. | Somatic cell genetic analysis of regulation of expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6935672 |
| Kinsella BT et al. | Posttranslational modification of Ha-ras p21 by farnesyl versus geranylgeranyl isoprenoids is determined by the COOH-terminal amino acid. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1924354 |
| Xiong M et al. | Scalable production of mechanically tunable block polymers from sugar. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24912182 |
| Casey PJ et al. | p21ras is modified by a farnesyl isoprenoid. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2682646 |
| Mumby SM et al. | G protein gamma subunits contain a 20-carbon isoprenoid. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2116011 |
| Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
| Goldstein JL et al. | Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor. | 1975 | Proc. Natl. Acad. Sci. U.S.A. | pmid:236556 |
| Kotti TJ et al. | Brain cholesterol turnover required for geranylgeraniol production and learning in mice. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16505352 |
| Wang Z et al. | Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24367099 |
| Khosravi-Far R et al. | Isoprenoid modification of rab proteins terminating in CC or CXC motifs. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1648736 |
| Clendening JW et al. | Dysregulation of the mevalonate pathway promotes transformation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20696928 |
| Loiseau L et al. | ErpA, an iron sulfur (Fe S) protein of the A-type essential for respiratory metabolism in Escherichia coli. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17698959 |
| Arebalo RE et al. | In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6256737 |
| Rohdich F et al. | Studies on the nonmevalonate terpene biosynthetic pathway: metabolic role of IspH (LytB) protein. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11818558 |
| Dudareva N et al. | The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15630092 |
| Hecht S et al. | Studies on the nonmevalonate pathway to terpenes: the role of the GcpE (IspG) protein. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11752431 |
| Money T et al. | Biosynthesis of the indole alkaloids. | 1965 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5222559 |
| Lange BM et al. | A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9482845 |
| Rao S et al. | Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10393901 |
| Hampton RY and Bhakta H | Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9371780 |
| Takahashi S et al. | A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9707569 |
| Chang TY et al. | Isolation and partial characterization of a cholesterol-requiring mutant of Chinese hamster ovary cells. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:265577 |
| McNamara DJ et al. | Measurement of daily cholesterol synthesis rates in man by assay of the fractional conversion of mevalonic acid to cholesterol. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:268653 |
| James G et al. | Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8633088 |
| Balasubramaniam S et al. | Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16260 |
| Zheng YH et al. | Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12824470 |
| Beg ZH et al. | In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6594693 |