Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
DiNicolantonio JJ CoQ10 and L-carnitine for statin myalgia? 2012 Expert Rev Cardiovasc Ther pmid:23190071
Aliferis KA and Jabaji S FT-ICR/MS and GC-EI/MS metabolomics networking unravels global potato sprout's responses to Rhizoctonia solani infection. 2012 PLoS ONE pmid:22880040
Zaidi N et al. ATP-citrate lyase: a key player in cancer metabolism. 2012 Cancer Res. pmid:22787121
Matsuoka T et al. An ultrasensitive enzymatic method for measuring mevalonic acid in serum. 2012 J. Lipid Res. pmid:22715156
Shi Z and Ruvkun G The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22396595
Hong SY et al. Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. 2012 J. Appl. Microbiol. pmid:22519412
Iwata A et al. Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. 2012 Clin. Exp. Immunol. pmid:22471285
Luvai A et al. Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. 2012 Clin Med Insights Cardiol pmid:22442638
Lachenmeier DW et al. NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements. 2012 Chin Med pmid:22439629
Mosqueda J et al. Current advances in detection and treatment of babesiosis. 2012 Curr. Med. Chem. pmid:22360483
Hyldgaard M et al. Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. 2012 Front Microbiol pmid:22291693
Ma Y et al. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. 2012 J. Exp. Bot. pmid:22291132
Keizer HG The "Mevalonate hypothesis": a cholesterol-independent alternative for the etiology of atherosclerosis. 2012 Lipids Health Dis pmid:23122424
Freed-Pastor WA et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. 2012 Cell pmid:22265415
Angaman DM et al. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. 2012 Plant Methods pmid:22243738
Yano K Lipid metabolic pathways as lung cancer therapeutic targets: a computational study. 2012 Int. J. Mol. Med. pmid:22211244
Shimane M et al. Mevalonate-dependent enzymatic synthesis of amorphadiene driven by an ATP-regeneration system using polyphosphate kinase. 2012 Biosci. Biotechnol. Biochem. pmid:22878192
Mans RA et al. Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. 2012 Neuroscience pmid:22192838
Zhou K et al. Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production. 2012 PLoS ONE pmid:23133596
Fuhrmeister J et al. Prooxidative toxicity and selenoprotein suppression by cerivastatin in muscle cells. 2012 Toxicol. Lett. pmid:23092657
Scalcinati G et al. Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae. 2012 Microb. Cell Fact. pmid:22938570
Li X et al. Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains. 2012 Genet. Sel. Evol. pmid:22682430
Baadhe RR et al. Development of petri net-based dynamic model for improved production of farnesyl pyrophosphate by integrating mevalonate and methylerythritol phosphate pathways in yeast. 2012 Appl. Biochem. Biotechnol. pmid:22350871
Panicker SP et al. Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia. 2012 PLoS ONE pmid:22685570
Guo H et al. Rosuvastatin may modulate insulin signaling and inhibit atherogenesis beyond its plasma cholesterol-lowering effect in insulin-resistant mice. 2012 Cardiovasc Drugs Ther pmid:22918601
Trapani L et al. 3-hydroxy 3-methylglutaryl coenzyme A reductase inhibition impairs muscle regeneration. 2012 J. Cell. Biochem. pmid:22274883
Hamano T et al. Pitavastatin decreases tau levels via the inactivation of Rho/ROCK. 2012 Neurobiol. Aging pmid:22133277
Nürenberg G and Volmer DA The analytical determination of isoprenoid intermediates from the mevalonate pathway. 2012 Anal Bioanal Chem pmid:21789486
Wu S et al. Engineering triterpene metabolism in tobacco. 2012 Planta pmid:22729821
Hu W et al. Statins synergize dexamethasone-induced adipocyte fatty acid binding protein expression in macrophages. 2012 Atherosclerosis pmid:22503826
Song AA et al. Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production. 2012 PLoS ONE pmid:23300671
Partow S et al. Reconstruction and evaluation of the synthetic bacterial MEP pathway in Saccharomyces cerevisiae. 2012 PLoS ONE pmid:23285068
Yang D et al. Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. 2012 PLoS ONE pmid:23209548
Hussain MS et al. Current approaches toward production of secondary plant metabolites. 2012 J Pharm Bioallied Sci pmid:22368394
Iguchi K [Effect of bisphosphonates on anticancer activity in prostate cancer cells]. 2012 Yakugaku Zasshi pmid:23023419
Haines BE et al. Molecular modeling of the reaction pathway and hydride transfer reactions of HMG-CoA reductase. 2012 Biochemistry pmid:22971202
Coscia M et al. Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells. 2012 Blood pmid:22932792
Garjani A et al. Ambivalent effects of atorvastatin on angiogenesis, epidermal cell proliferation and tumorgenesis in animal models. 2012 Iran. Biomed. J. pmid:22801278
Ginestier C et al. p53 and cancer stem cells: the mevalonate connexion. 2012 Cell Cycle pmid:22751434
Roy A et al. Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. 2012 PLoS ONE pmid:22723850
Ghavami S et al. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. 2012 Cell Death Dis pmid:22717585
Ohsawa M et al. Effect of spinally administered simvastatin on the formalin-induced nociceptive response in mice. 2012 J. Pharmacol. Sci. pmid:22510521
Chow KS et al. Metabolic routes affecting rubber biosynthesis in Hevea brasiliensis latex. 2012 J. Exp. Bot. pmid:22162870
Reiniers MJ et al. 2',7'-Dichlorofluorescein is not a probe for the detection of reactive oxygen and nitrogen species. 2012 J. Hepatol. pmid:22127279
Plée-Gautier E et al. Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism. 2012 Biochem. Pharmacol. pmid:22634049
Paintlia AS et al. Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis. 2012 Am. J. Pathol. pmid:22796435
Zhang B et al. Interference in mevalonate pathway ameliorates homocysteine-induced endothelium-dysfunction. 2012 Eur. J. Pharmacol. pmid:22796672
Roullet JB et al. No evidence for mevalonate shunting in moderately affected children with Smith-Lemli-Opitz syndrome. 2012 J. Inherit. Metab. Dis. pmid:22391996
Barta ML et al. Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. 2012 Biochemistry pmid:22734632
Jiang Q et al. Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide. 2012 Int. J. Cancer pmid:21400505