Hu ZY et al. |
Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. |
1987 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:3479785
|
Pronin AN and Gautam N |
Interaction between G-protein beta and gamma subunit types is selective. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1631113
|
Liu GC et al. |
Measurement of cholesterol synthesis in man by isotope kinetics of squalene. |
1975 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1060141
|
Kotti T et al. |
Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18685105
|
Epstein WW et al. |
Quantitation of prenylcysteines by a selective cleavage reaction. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1946384
|
Mizuno T et al. |
A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1907371
|
Roullet JB et al. |
Mevalonate availability and cardiovascular functions. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8265617
|
Shi Z and Ruvkun G |
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22396595
|
Jakóbisiak M et al. |
Cell cycle-specific effects of lovastatin. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1673788
|
Jackson JH et al. |
Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. |
1990 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:2183224
|
Saito Y et al. |
Animal cell mutants defective in sterol metabolism: a specific selection procedure and partial characterization of defects. |
1977 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:269426
|
Sinensky M and Logel J |
Defective macromolecule biosynthesis and cell-cycle progression in a mammalian cell starved for mevalonate. |
1985 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:2582409
|
Cuthbert JA and Lipsky PE |
Modulation of human lymphocyte responses by low density lipoproteins (LDL): enhancement but not immunosuppression is mediated by LDL receptors. |
1984 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:6087331
|
Tianero MD et al. |
Metabolic model for diversity-generating biosynthesis. |
2016 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26831074
|
Goldstein JL and Brown MS |
Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. |
1973 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:4355366
|
Huneeus VQ et al. |
Isopentenyladenine as a mediator of mevalonate-regulated DNA replication. |
1980 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:6934516
|
Kopito RR and Brunengraber H |
(R)-mevalonate excretion in human and rat urines. |
1980 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:6255462
|
Quesney-Huneeus V et al. |
Essential role for mevalonate synthesis in DNA replication. |
1979 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:291922
|
Venkateshwaran M et al. |
A role for the mevalonate pathway in early plant symbiotic signaling. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26199419
|
Brown MS and Goldstein JL |
Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. |
1974 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:4362634
|
Autefage H et al. |
Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25831522
|
Polotskaia A et al. |
Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25733866
|
Fisher JE et al. |
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9874784
|
Giron MD et al. |
Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. |
1994 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8022795
|
Parmryd I et al. |
Protein prenylation in spinach chloroplasts. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10468564
|
Lai RK et al. |
The gamma subunit of transducin is farnesylated. |
1990 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:2217200
|
Sinensky M et al. |
Somatic cell genetic analysis of regulation of expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
1980 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:6935672
|
Farnsworth CC et al. |
C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1906176
|
Xiong M et al. |
Scalable production of mechanically tunable block polymers from sugar. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24912182
|
Casey PJ et al. |
p21ras is modified by a farnesyl isoprenoid. |
1989 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:2682646
|
Mumby SM et al. |
G protein gamma subunits contain a 20-carbon isoprenoid. |
1990 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:2116011
|
Stone KJ and Strominger JL |
Inhibition of sterol biosynthesis by bacitracin. |
1972 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:4338587
|
Goldstein JL et al. |
Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor. |
1975 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:236556
|
Kotti TJ et al. |
Brain cholesterol turnover required for geranylgeraniol production and learning in mice. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16505352
|
Khosravi-Far R et al. |
Isoprenoid modification of rab proteins terminating in CC or CXC motifs. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1648736
|
Loiseau L et al. |
ErpA, an iron sulfur (Fe S) protein of the A-type essential for respiratory metabolism in Escherichia coli. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:17698959
|
Arebalo RE et al. |
In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone. |
1980 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:6256737
|
Rohdich F et al. |
Studies on the nonmevalonate terpene biosynthetic pathway: metabolic role of IspH (LytB) protein. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11818558
|
Dudareva N et al. |
The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. |
2005 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15630092
|
Money T et al. |
Biosynthesis of the indole alkaloids. |
1965 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:5222559
|
Ohyama K et al. |
Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19139393
|
Lange BM et al. |
A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9482845
|
Rao S et al. |
Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10393901
|
Hampton RY and Bhakta H |
Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase. |
1997 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9371780
|
Chang TY et al. |
Isolation and partial characterization of a cholesterol-requiring mutant of Chinese hamster ovary cells. |
1977 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:265577
|
McNamara DJ et al. |
Measurement of daily cholesterol synthesis rates in man by assay of the fractional conversion of mevalonic acid to cholesterol. |
1977 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:268653
|
James G et al. |
Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells. |
1996 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8633088
|
Balasubramaniam S et al. |
Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities. |
1977 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16260
|
Zheng YH et al. |
Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12824470
|
Beg ZH et al. |
In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone. |
1984 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:6594693
|