Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Peutz-Jeghers Syndrome D010580 2 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Celiac Disease D002446 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Glioblastoma D005909 27 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Hypothyroidism D007037 32 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Thrombosis D013927 49 associated lipids
Leukemia D007938 74 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

Download all related citations
Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Aliferis KA and Jabaji S FT-ICR/MS and GC-EI/MS metabolomics networking unravels global potato sprout's responses to Rhizoctonia solani infection. 2012 PLoS ONE pmid:22880040
Zaidi N et al. ATP-citrate lyase: a key player in cancer metabolism. 2012 Cancer Res. pmid:22787121
Matsuoka T et al. An ultrasensitive enzymatic method for measuring mevalonic acid in serum. 2012 J. Lipid Res. pmid:22715156
Van Laar TA et al. Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi. 2012 PLoS ONE pmid:22675445
Ginestier C et al. Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target. 2012 Stem Cells pmid:22605458
Liu D et al. The genome of Ganoderma lucidum provides insights into triterpenes biosynthesis and wood degradation [corrected]. 2012 PLoS ONE pmid:22567134
Yang J et al. Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. 2012 PLoS ONE pmid:22558074
Shi Z and Ruvkun G The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22396595
Thurnher M et al. Novel aspects of mevalonate pathway inhibitors as antitumor agents. 2012 Clin. Cancer Res. pmid:22529099
Hong SY et al. Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. 2012 J. Appl. Microbiol. pmid:22519412
Mosqueda J et al. Current advances in detection and treatment of babesiosis. 2012 Curr. Med. Chem. pmid:22360483
Hyldgaard M et al. Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. 2012 Front Microbiol pmid:22291693
Ma Y et al. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. 2012 J. Exp. Bot. pmid:22291132
Keizer HG The "Mevalonate hypothesis": a cholesterol-independent alternative for the etiology of atherosclerosis. 2012 Lipids Health Dis pmid:23122424
Freed-Pastor WA et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. 2012 Cell pmid:22265415
Angaman DM et al. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. 2012 Plant Methods pmid:22243738
Yano K Lipid metabolic pathways as lung cancer therapeutic targets: a computational study. 2012 Int. J. Mol. Med. pmid:22211244
Mans RA et al. Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. 2012 Neuroscience pmid:22192838
Fu X et al. Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. 2012 J. Exp. Bot. pmid:21994170
Murphy LA et al. Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation. 2012 Toxicol. Appl. Pharmacol. pmid:22361350
Zhou K et al. Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production. 2012 PLoS ONE pmid:23133596
Fuhrmeister J et al. Prooxidative toxicity and selenoprotein suppression by cerivastatin in muscle cells. 2012 Toxicol. Lett. pmid:23092657
Yasmin S et al. Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22106303
Li X et al. Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains. 2012 Genet. Sel. Evol. pmid:22682430
Baadhe RR et al. Development of petri net-based dynamic model for improved production of farnesyl pyrophosphate by integrating mevalonate and methylerythritol phosphate pathways in yeast. 2012 Appl. Biochem. Biotechnol. pmid:22350871
Panicker SP et al. Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia. 2012 PLoS ONE pmid:22685570
Guo H et al. Rosuvastatin may modulate insulin signaling and inhibit atherogenesis beyond its plasma cholesterol-lowering effect in insulin-resistant mice. 2012 Cardiovasc Drugs Ther pmid:22918601
Trapani L et al. 3-hydroxy 3-methylglutaryl coenzyme A reductase inhibition impairs muscle regeneration. 2012 J. Cell. Biochem. pmid:22274883
Hamano T et al. Pitavastatin decreases tau levels via the inactivation of Rho/ROCK. 2012 Neurobiol. Aging pmid:22133277
Nürenberg G and Volmer DA The analytical determination of isoprenoid intermediates from the mevalonate pathway. 2012 Anal Bioanal Chem pmid:21789486
Garcia-Ruiz C et al. Statins and protein prenylation in cancer cell biology and therapy. 2012 Anticancer Agents Med Chem pmid:22413970
Wu S et al. Engineering triterpene metabolism in tobacco. 2012 Planta pmid:22729821
Hu W et al. Statins synergize dexamethasone-induced adipocyte fatty acid binding protein expression in macrophages. 2012 Atherosclerosis pmid:22503826
Song AA et al. Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production. 2012 PLoS ONE pmid:23300671
Partow S et al. Reconstruction and evaluation of the synthetic bacterial MEP pathway in Saccharomyces cerevisiae. 2012 PLoS ONE pmid:23285068
Yang D et al. Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. 2012 PLoS ONE pmid:23209548
Iguchi K [Effect of bisphosphonates on anticancer activity in prostate cancer cells]. 2012 Yakugaku Zasshi pmid:23023419
Malenda A et al. Statins impair glucose uptake in tumor cells. 2012 Neoplasia pmid:22577346
Ginestier C et al. p53 and cancer stem cells: the mevalonate connexion. 2012 Cell Cycle pmid:22751434
Roy A et al. Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. 2012 PLoS ONE pmid:22723850
Ghavami S et al. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. 2012 Cell Death Dis pmid:22717585
Ohsawa M et al. Effect of spinally administered simvastatin on the formalin-induced nociceptive response in mice. 2012 J. Pharmacol. Sci. pmid:22510521
Chow KS et al. Metabolic routes affecting rubber biosynthesis in Hevea brasiliensis latex. 2012 J. Exp. Bot. pmid:22162870
Reiniers MJ et al. 2',7'-Dichlorofluorescein is not a probe for the detection of reactive oxygen and nitrogen species. 2012 J. Hepatol. pmid:22127279
Khasnavis S and Pahan K Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. 2012 J Neuroimmune Pharmacol pmid:21701815
Plée-Gautier E et al. Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism. 2012 Biochem. Pharmacol. pmid:22634049
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
Conrado RJ et al. DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. 2012 Nucleic Acids Res. pmid:22021385
Barta ML et al. Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. 2012 Biochemistry pmid:22734632
Li J et al. Atorvastatin inhibits myocardin expression in vascular smooth muscle cells. 2012 Hypertension pmid:22615115