Ramachandran CK and Shah SN |
Decarboxylation of mevalonate pyrophosphate is one rate-limiting step in hepatic cholesterol synthesis in suckling and weaned rats. |
1976 |
Biochem. Biophys. Res. Commun. |
pmid:177019
|
Nes WD et al. |
Metabolism of mevalonic acid to long chain fatty alcohols in an insect. |
1982 |
Biochem. Biophys. Res. Commun. |
pmid:7181890
|
Rao GS and Ramasarma T |
ATP in the regulation of cholesterol biosynthesis- a supra-energetic role. |
1972 |
Biochem. Biophys. Res. Commun. |
pmid:5077855
|
Wang Y et al. |
24S,25-Epoxycholesterol in mouse and rat brain. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24832732
|
Heintz R et al. |
Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. |
1972 |
Biochem. Biophys. Res. Commun. |
pmid:4344813
|
Chan PC et al. |
Lovastatin increases surface low density lipoprotein receptor expression by retarding the receptor internalization rate in proliferating lymphocytes. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9196047
|
Szkopińska A et al. |
The regulation of activity of main mevalonic acid pathway enzymes: farnesyl diphosphate synthase, 3-hydroxy-3-methylglutaryl-CoA reductase, and squalene synthase in yeast Saccharomyces cerevisiae. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10623644
|
Sagami H et al. |
Novel isoprenoid modified proteins in Halobacteria. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:8093082
|
Hu ZY et al. |
Neurosteroids: steroidogenesis in primary cultures of rat glial cells after release of aminoglutethimide blockade. |
1989 |
Biochem. Biophys. Res. Commun. |
pmid:2735928
|
Sablé-Amplis R and Sicart R |
Evidence for negative feedback control of cholesterogenesis from mevalonate in liver: absence in the intestine of guinea pigs fed a 0.5% cholesterol diet. |
1982 |
Biochem. Biophys. Res. Commun. |
pmid:7181883
|
Cenedella RJ et al. |
Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1510688
|
Keller RK and Fliesler SJ |
Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10600541
|
Fuhrman B et al. |
Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9168909
|
Polo MP and de Bravo MG |
Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2. |
2006 |
Biochem. Cell Biol. |
pmid:16462894
|
Polo MP et al. |
Effect of ethanol on cell growth and cholesterol metabolism in cultured Hep G2 cells. |
2003 |
Biochem. Cell Biol. |
pmid:14663504
|
Silber JR et al. |
The effect of mevalonic acid deprivation on enzymes of DNA replication in cells emerging from quiescence. |
1992 |
Biochem. J. |
pmid:1281982
|
Malathi P and Ganguly J |
Studies on metabolism of vitamin A. 8. Effect of ascorbate on isoprenoid metabolism in vitamin A-deficient rats. |
1964 |
Biochem. J. |
pmid:5837438
|
Ellsworth JL et al. |
Evidence for sterol-independent regulation of low-density lipoprotein receptor activity in Hep-G2 cells. |
1991 |
Biochem. J. |
pmid:1930137
|
Konrad Z and Eichler J |
Lipid modification of proteins in Archaea: attachment of a mevalonic acid-based lipid moiety to the surface-layer glycoprotein of Haloferax volcanii follows protein translocation. |
2002 |
Biochem. J. |
pmid:12069685
|
Henry A et al. |
Dolichol biosynthesis in human malignant cells. |
1991 |
Biochem. J. |
pmid:1654890
|
Bolaños JP et al. |
Inhibition of sterol but not fatty acid synthesis by valproate in developing rat brain in vivo. |
1990 |
Biochem. J. |
pmid:2264830
|
Iglesias J and Gibbons GF |
Regulation of hepatic cholesterol biosynthesis. Effects of a cytochrome P-450 inhibitor on the formation and metabolism of oxygenated sterol products of lanosterol. |
1989 |
Biochem. J. |
pmid:2604729
|
Richards JB and Hemming FW |
Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. |
1972 |
Biochem. J. |
pmid:4643705
|
Smith AG and Goad LJ |
Sterol biosynthesis in the echinoderm Asterias rubens. |
1975 |
Biochem. J. |
pmid:1147897
|
Wellburn AR and Hampp R |
Uptake of mevalonate and acetate during plastid development. |
1976 |
Biochem. J. |
pmid:985424
|
Konrad M and Merz WE |
Long-term effect of cyclic AMP on N-glycosylation is caused by an increase in the activity of the cis-prenyltransferase. |
1996 |
Biochem. J. |
pmid:8687403
|
Flint AP |
The activity and kinetic properties of mevalonate kinase in superovulated rat ovary. |
1970 |
Biochem. J. |
pmid:4321929
|
Green TR and Baisted DJ |
Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination. |
1972 |
Biochem. J. |
pmid:4348263
|
Azrolan NI and Coleman PS |
A discoordinate increase in the cellular amount of 3-hydroxy-3-methylglutaryl-CoA reductase results in the loss of rate-limiting control over cholesterogenesis in a tumour cell-free system. |
1989 |
Biochem. J. |
pmid:2705993
|
Wilton DC |
The effect of excess mevalonic acid on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. |
1985 |
Biochem. J. |
pmid:3929773
|
Wilton DC |
The effect of cholesterol on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. |
1983 |
Biochem. J. |
pmid:6418144
|
Disch A et al. |
Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. |
1998 |
Biochem. J. |
pmid:9657979
|
Swift IE and Milborrow BV |
Retention of the 4-pro-R hydrogen atom of mevalonate at C-2,2' of bacterioruberin in Halobacterium halobium. |
1980 |
Biochem. J. |
pmid:7406867
|
Burt VT et al. |
The formation of menaquinone-4 (vitamin K) and its oxide in some marine invertebrates. |
1977 |
Biochem. J. |
pmid:849285
|
Gibbons GF and Mitropoulos KA |
The effect of carbon monoxide on the nature of the accumulated 4,4-dimethyl sterol precursors of cholesterol during its biosynthesis from (2-14C)mevalonic acid in vitro. |
1973 |
Biochem. J. |
pmid:4724584
|
Swift IE and Milborrow BV |
Stereochemistry of allene biosynthesis and the formation of the acetylenic carotenoid diadinoxanthin and peridinin (C37) from neoxanthin. |
1981 |
Biochem. J. |
pmid:7337715
|
Jayaram M and Raman TS |
Metabolism of ergosterol in the larva of the rice moth (Corcyra cephalonica St.). |
1972 |
Biochem. J. |
pmid:5085614
|
Nave JF et al. |
Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. |
1985 |
Biochem. J. |
pmid:2986604
|
Martin HG and Thorne KJ |
Synthesis of radioactive dolichol from (4S-3H)mevalonate in the regenerating rat liver. |
1974 |
Biochem. J. |
pmid:4822733
|
Moshier SE and Chapman DJ |
Biosynthetic studies on aromatic carotenoids. Biosynthesis of chlorobactene. |
1973 |
Biochem. J. |
pmid:4774401
|
Gregory KW et al. |
Diurnal variations in rat liver 3-hydroxy-3-methylglutaryl-Coenzyme A reductase activity in relation to feeding. |
1972 |
Biochem. J. |
pmid:4656802
|
Kam NT et al. |
Effect of lovastatin on acyl-CoA: cholesterol O-acyltransferase (ACAT) activity and the basolateral-membrane secretion of newly synthesized lipids by CaCo-2 cells. |
1990 |
Biochem. J. |
pmid:2268271
|
Hornby GM and Boyd GS |
The origin of lanosta-7,24-dienol in rat skin. |
1971 |
Biochem. J. |
pmid:5131739
|
Richards JB et al. |
Dolichol phosphates as acceptors of mannose from guanosine diphosphate mannose in liver systems. |
1971 |
Biochem. J. |
pmid:5131017
|
Thorne KJ and Barker DC |
The bactoprenol content of plasma and mesosome membranes from Lactobacillus casei. |
1971 |
Biochem. J. |
pmid:5001951
|
Milborrow BV and Noddle RC |
Conversion of 5-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-methylpenta-cis-2-trans-4-dienoic acid into abscisic acid in plants. |
1970 |
Biochem. J. |
pmid:5493506
|
Green TR and Baisted DJ |
Development of the squalene-synthesizing system during early stages of pea seed germination. |
1971 |
Biochem. J. |
pmid:4335540
|
Bolger LM et al. |
Biosynthesis of 24-ethylcholesta-5,22,25-trien-3-beta-ol, a new sterol from Clerodendrum campbellii. |
1970 |
Biochem. J. |
pmid:5472151
|
Ginger ML et al. |
Elucidation of carbon sources used for the biosynthesis of fatty acids and sterols in the trypanosomatid Leishmania mexicana. |
1999 |
Biochem. J. |
pmid:10455027
|
Gough DP et al. |
The characterization of undecaprenol of Lactobacillus plantarum. |
1970 |
Biochem. J. |
pmid:5472148
|
Atkin SD et al. |
The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. |
1972 |
Biochem. J. |
pmid:4655417
|
De Souza NJ et al. |
Studies on insect moulting hormones: biosynthesis of ponasterone A and ecdysterone from [2-14C] mevalonate in Taxus baccata. |
1969 |
Biochem. J. |
pmid:5343810
|
Bolger LM et al. |
Incorporation of [2-14C] mevalonic acid into 28-isofucosterol by leaves of Pisum sativum. |
1969 |
Biochem. J. |
pmid:5343809
|
Hepper CM and Audley BG |
Th biosynthesis of rubber from beta-hydroxy-beta-methylgluarylcoenzyme A in Hevea brasiliensis latex. |
1969 |
Biochem. J. |
pmid:4390212
|
Buggy MJ et al. |
Stereochemistry of phytoene biosynthesis by isolated chloroplasts. |
1969 |
Biochem. J. |
pmid:4309532
|
Robinson DR and Ryback G |
Incorporation of tritium from [(4R)-4-3H]mevalonate into abscisic acid. |
1969 |
Biochem. J. |
pmid:5821014
|
Rees HH et al. |
Studies in phytosterol biosynthesis. Mechanism of biosynthesis of cycloartenol. |
1968 |
Biochem. J. |
pmid:4297048
|
West CA |
Gibberellins and their biosynthesis. |
1969 |
Biochem. J. |
pmid:5810062
|
Francis MJ and Allcock C |
Monoterpene beta-D-glucosides in roses: isolation and formation from DL-2-14C mevalonate. |
1969 |
Biochem. J. |
pmid:5807204
|
Reid WW |
Effect of SKF7997 and SKF525 on diterpene and sterol biosynthesis in Gibberella fujikori from [2-14C] mevalonate. |
1969 |
Biochem. J. |
pmid:5807203
|
Gray JC and Kekwick RG |
Mevalonate kinase from etiolated cotyledons of French beans. |
1969 |
Biochem. J. |
pmid:5807202
|
Austin DG et al. |
Trisporic acid biosynthesis and carotenogenesis in Blakesleea trispora. |
1969 |
Biochem. J. |
pmid:5807198
|
Hill HM and Rogers LJ |
Conversion of lycopene into beta-carotene by chloroplasts of higher plants. |
1969 |
Biochem. J. |
pmid:5807194
|
Barr RM and Hemming FW |
Polyprenol phosphate as an acceptor of mannose from guanosine diphosphate mannose in Aspergillus niger. |
1972 |
Biochem. J. |
pmid:5073732
|
Liuzzi A and Foppen FH |
Sterol-like compound from sensory ganglia. Effect of a nerve growth factor and insulin on its biosynthesis. |
1968 |
Biochem. J. |
pmid:5641875
|
Parsons RB et al. |
Statins inhibit the dimerization of beta-secretase via both isoprenoid- and cholesterol-mediated mechanisms. |
2006 |
Biochem. J. |
pmid:16803455
|
Williams RJ et al. |
The biosynthesis of cyclic carotenes. |
1967 |
Biochem. J. |
pmid:6060456
|
Wieckowski S and Goodwin TW |
Incorporation of DL-[2-14C]mevalonic acid lactone into beta-carotene and the phytol side chain of chlorophyll in cotyledons of four species of pine seedlings. |
1967 |
Biochem. J. |
pmid:6060454
|
Gough DP and Hemming FW |
The stereochemistry of betulaprenol biosynthesis. |
1967 |
Biochem. J. |
pmid:6056617
|
Rodwell VW |
Cholesterol regulation of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
1972 |
Biochem. J. |
pmid:5085556
|
Rees HH et al. |
The biosynthesis of beta-amyrin. Mechanism of squalene cyclization. |
1968 |
Biochem. J. |
pmid:5639923
|
Rogers LJ et al. |
Mevalonate-kinase isoenzymes in plant cells. |
1966 |
Biochem. J. |
pmid:5968528
|
Goad LJ and Goodwin TW |
The biosynthesis of sterols in higher plants. |
1966 |
Biochem. J. |
pmid:5964970
|
Rees HH et al. |
The stereospecific biosynthesis of plant sterols and alpha- and beta-amyrin. |
1966 |
Biochem. J. |
pmid:5964969
|
Rogers LJ et al. |
Intracellular localization of mevalonate-activating enzymes in plant cells. |
1966 |
Biochem. J. |
pmid:5947149
|
Treharne KJ et al. |
Incorporation of [14C] carbon dioxide and [2-14C] mevalonic acid into terpenoids of higher plants during chloroplast development. |
1966 |
Biochem. J. |
pmid:5965341
|
Fears R |
The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function. |
1981 |
Biochem. J. |
pmid:7039614
|
Thorne KJ and Kodicek E |
The structure of bactoprenol, a lipid formed by lactobacilli from mevalonic acid. |
1966 |
Biochem. J. |
pmid:5965329
|
Overton KH and Roberts FM |
Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. |
1974 |
Biochem. J. |
pmid:4468823
|
Molowa DT and Cimis GM |
Co-ordinate regulation of low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase and synthase gene expression in HepG2 cells. |
1989 |
Biochem. J. |
pmid:2569863
|
Joshi VC et al. |
Biosynthetic relationship between ubichromenol and ubiquinone. |
1964 |
Biochem. J. |
pmid:5838088
|
Gavigan SJ and Knight BL |
The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. |
1983 |
Biochem. J. |
pmid:6651782
|
Campos N et al. |
Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. |
2001 |
Biochem. J. |
pmid:11115399
|
Milborrow BV |
Stereochemical aspects of the formation of double bonds in abscisic acid. |
1972 |
Biochem. J. |
pmid:4643698
|
RAMASARMA T and RAMAKRISHNAN T |
Incorporation of [2-14C]mevalonic acid and [2-14C]acetic acid into lipids of mycobacteria. |
1961 |
Biochem. J. |
pmid:14038591
|
Banthorpe DV et al. |
Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium graveolens and Rosa dilecta. |
1972 |
Biochem. J. |
pmid:4348258
|
Campia I et al. |
Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes. |
2012 |
Biochem. J. |
pmid:22845468
|
Knöss W et al. |
Biosynthesis of the labdane diterpene marrubiin in Marrubium vulgare via a non-mevalonate pathway. |
1997 |
Biochem. J. |
pmid:9291117
|
Disch A et al. |
Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. |
1998 |
Biochem. J. |
pmid:9531505
|
Farrell FX et al. |
Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated. |
1993 |
Biochem. J. |
pmid:8424780
|
Percy-Robb IW and Boyd GS |
The synthesis of bile acids in perfused rat liver subjected to chronic biliary drainage. |
1970 |
Biochem. J. |
pmid:5472179
|
Goad LJ et al. |
Incorporation of (2-14C, (5r)-5-3H1) mevalonic acid into cholesterol by a rat liver homogenate and into beta-sitosterol and 28-isofucosterol by larix decidua leaves. |
1969 |
Biochem. J. |
pmid:5348842
|
Barr RM and Hemming FW |
Polyprenols of Aspergillus niger. Their characterization, biosynthesis and subcellular distribution. |
1972 |
Biochem. J. |
pmid:5073731
|
Wade DP et al. |
Independent regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and chylomicron remnant receptor activities in rat liver. |
1984 |
Biochem. J. |
pmid:6324750
|
Thorne KJ |
Incorporation of radioactive mevalonate into C50 and C55 phenols by Streptococcus mutans. |
1973 |
Biochem. J. |
pmid:4772282
|
Derksen A et al. |
Non-human primate platelets and arterial tissue cannot convert preformed [14C]lanosterol into[14C]cholesterol in vivo. |
1976 |
Biochem. J. |
pmid:822845
|
Grönroos E et al. |
Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. |
1996 |
Biochem. J. |
pmid:8645211
|
Scharf SS and Simpson KL |
Attempts to detect lycopersene formation in yeast. |
1968 |
Biochem. J. |
pmid:5753091
|
Booth R et al. |
The effect of dietary cholesterol on cholesterol biosynthesis and other processes in mammalian liver. |
1971 |
Biochem. J. |
pmid:5124798
|
Li G et al. |
Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins. |
1993 |
Biochem. J. |
pmid:8424783
|