Redding-Johanson AM et al. |
Targeted proteomics for metabolic pathway optimization: application to terpene production. |
2011 |
Metab. Eng. |
pmid:21215324
|
Huang SH et al. |
Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin. |
2011 |
PLoS ONE |
pmid:21966365
|
Singh NK et al. |
12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. |
2011 |
Blood |
pmid:21841162
|
Luo H et al. |
Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. |
2011 |
BMC Genomics |
pmid:22369100
|
Nes WD |
Biosynthesis of cholesterol and other sterols. |
2011 |
Chem. Rev. |
pmid:21902244
|
Ali OF et al. |
Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. |
2011 |
Respir. Res. |
pmid:21999923
|
Bergman P et al. |
Studies on the antibacterial effects of statins--in vitro and in vivo. |
2011 |
PLoS ONE |
pmid:21912631
|
Emma F et al. |
Renal mitochondrial cytopathies. |
2011 |
Int J Nephrol |
pmid:21811680
|
Ageenko NV et al. |
Expression of Pigment Cell-Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius. |
2011 |
Evid Based Complement Alternat Med |
pmid:21804858
|
Cheng G et al. |
Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. |
2011 |
Cancer Biol. Ther. |
pmid:21799303
|
Peng LF et al. |
Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. |
2011 |
J. Infect. Dis. |
pmid:21791663
|
Waldron J and Webster C |
Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. |
2011 |
Ann. Clin. Biochem. |
pmid:21355014
|
Scheller EL et al. |
Bisphosphonates inhibit expression of p63 by oral keratinocytes. |
2011 |
J. Dent. Res. |
pmid:21551338
|
Kishi T |
Mevalonate pathway is a novel target for hypertension. |
2011 |
Circ. J. |
pmid:21532185
|
Sakamoto K et al. |
Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes. |
2011 |
BMC Musculoskelet Disord |
pmid:21524281
|
Han J et al. |
Alteration of enzyme expressions in mevalonate pathway: possible role for cardiovascular remodeling in spontaneously hypertensive rats. |
2011 |
Circ. J. |
pmid:21467659
|
Siddals KW et al. |
Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization. |
2011 |
J. Biol. Chem. |
pmid:21454560
|
Brock NL et al. |
Biosynthesis of sesqui- and diterpenes by the gibberellin producer Fusarium fujikuroi. |
2011 |
Chembiochem |
pmid:21990128
|
Soliman SS et al. |
Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways. |
2011 |
J. Nat. Prod. |
pmid:22103292
|
Mongélard G et al. |
Measurement of carbon flux through the MEP pathway for isoprenoid synthesis by (31)P-NMR spectroscopy after specific inhibition of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate reductase. Effect of light and temperature. |
2011 |
Plant Cell Environ. |
pmid:21443577
|
Zhang B et al. |
A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. |
2011 |
Biochemistry |
pmid:21438569
|
Henneman L et al. |
Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS. |
2011 |
Biochim. Biophys. Acta |
pmid:21237288
|
Kim RH et al. |
Bisphosphonates induce senescence in normal human oral keratinocytes. |
2011 |
J. Dent. Res. |
pmid:21427353
|
Kyathanahalli CN and Kowluru A |
A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGEâ‚‚. |
2011 |
Biochem. Pharmacol. |
pmid:21406184
|
Zhao Y et al. |
Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. |
2011 |
J. Invest. Dermatol. |
pmid:21390048
|
Blankier S et al. |
The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease. |
2011 |
Clin. Exp. Immunol. |
pmid:21361911
|
Ghavami S et al. |
Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. |
2011 |
PLoS ONE |
pmid:21304979
|
Ignea C et al. |
Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. |
2011 |
Microb. Cell Fact. |
pmid:21276210
|
Tsubaki M et al. |
Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma. |
2011 |
Cytokine |
pmid:21292498
|
Cluis CP et al. |
Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). |
2011 |
Metab. Eng. |
pmid:21986057
|
Relja B et al. |
Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK. |
2011 |
Int. J. Oncol. |
pmid:21206971
|
Tsuyuki R et al. |
Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride. |
2011 |
J. Agric. Food Chem. |
pmid:21299216
|
Nilsson S et al. |
Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells. |
2011 |
Cancer Lett. |
pmid:21356574
|
Liu Q et al. |
Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. |
2011 |
PLoS ONE |
pmid:21858047
|
Kimachi K et al. |
Zoledronic acid inhibits RANK expression and migration of osteoclast precursors during osteoclastogenesis. |
2011 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:21225243
|
Epplen R et al. |
Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. |
2011 |
Acta Oncol |
pmid:20429730
|
Jouneau S et al. |
Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. |
2011 |
PLoS ONE |
pmid:21826199
|
Lin Y et al. |
Triterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters. |
2011 |
Evid Based Complement Alternat Med |
pmid:19228775
|
Murtola TJ et al. |
Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL. |
2011 |
Eur. J. Pharmacol. |
pmid:22040920
|
Zhong WB et al. |
Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. |
2011 |
Biochem. Pharmacol. |
pmid:21907187
|
Issat T et al. |
Antitumor effects of the combination of cholesterol reducing drugs. |
2011 |
Oncol. Rep. |
pmid:21491092
|
Zeki AA et al. |
Statin drugs, metabolic pathways, and asthma: a therapeutic opportunity needing further research. |
2011 |
Drug Metab Lett |
pmid:21198438
|
Esemuede N et al. |
Lovastatin inhibits thrombospondin-1-induced smooth muscle cell chemotaxis. |
2011 |
J. Surg. Res. |
pmid:20338582
|
Soto G et al. |
Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation. |
2011 |
J. Exp. Bot. |
pmid:21908473
|
Wong DH et al. |
Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells. |
2011 |
Fertil. Steril. |
pmid:21907337
|
Kim YS et al. |
Increase of lycopene production by supplementing auxiliary carbon sources in metabolically engineered Escherichia coli. |
2011 |
Appl. Microbiol. Biotechnol. |
pmid:21246354
|
Jang HJ et al. |
Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. |
2011 |
Microb. Cell Fact. |
pmid:21801353
|
Schaafsma D et al. |
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. |
2011 |
Respir. Res. |
pmid:21864337
|
Barta ML et al. |
Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. |
2011 |
J. Biol. Chem. |
pmid:21561869
|
Yanae M et al. |
Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. |
2011 |
J. Exp. Clin. Cancer Res. |
pmid:21831290
|