Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Ginestier C et al. | Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target. | 2012 | Stem Cells | pmid:22605458 |
Liu D et al. | The genome of Ganoderma lucidum provides insights into triterpenes biosynthesis and wood degradation [corrected]. | 2012 | PLoS ONE | pmid:22567134 |
Yang J et al. | Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. | 2012 | PLoS ONE | pmid:22558074 |
Thurnher M et al. | Novel aspects of mevalonate pathway inhibitors as antitumor agents. | 2012 | Clin. Cancer Res. | pmid:22529099 |
Keizer HG | The "Mevalonate hypothesis": a cholesterol-independent alternative for the etiology of atherosclerosis. | 2012 | Lipids Health Dis | pmid:23122424 |
Fu X et al. | Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. | 2012 | J. Exp. Bot. | pmid:21994170 |
Zhou K et al. | Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production. | 2012 | PLoS ONE | pmid:23133596 |
Yang D et al. | Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. | 2012 | PLoS ONE | pmid:23209548 |
Iguchi K | [Effect of bisphosphonates on anticancer activity in prostate cancer cells]. | 2012 | Yakugaku Zasshi | pmid:23023419 |
Malenda A et al. | Statins impair glucose uptake in tumor cells. | 2012 | Neoplasia | pmid:22577346 |
Fatima T et al. | Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. | 2012 | PLoS ONE | pmid:22558083 |
Yokota K et al. | Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. | 2011 Jan-Feb | Clin. Exp. Rheumatol. | pmid:21345291 |
Redding-Johanson AM et al. | Targeted proteomics for metabolic pathway optimization: application to terpene production. | 2011 | Metab. Eng. | pmid:21215324 |
Singh NK et al. | 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. | 2011 | Blood | pmid:21841162 |
Ma SM et al. | Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases. | 2011 | Metab. Eng. | pmid:21810477 |
Luo H et al. | Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. | 2011 | BMC Genomics | pmid:22369100 |
Nes WD | Biosynthesis of cholesterol and other sterols. | 2011 | Chem. Rev. | pmid:21902244 |
Emma F et al. | Renal mitochondrial cytopathies. | 2011 | Int J Nephrol | pmid:21811680 |
Ageenko NV et al. | Expression of Pigment Cell-Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius. | 2011 | Evid Based Complement Alternat Med | pmid:21804858 |
Cheng G et al. | Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. | 2011 | Cancer Biol. Ther. | pmid:21799303 |
Peng LF et al. | Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. | 2011 | J. Infect. Dis. | pmid:21791663 |
Siddals KW et al. | Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization. | 2011 | J. Biol. Chem. | pmid:21454560 |
Brock NL et al. | Biosynthesis of sesqui- and diterpenes by the gibberellin producer Fusarium fujikuroi. | 2011 | Chembiochem | pmid:21990128 |
Mongélard G et al. | Measurement of carbon flux through the MEP pathway for isoprenoid synthesis by (31)P-NMR spectroscopy after specific inhibition of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate reductase. Effect of light and temperature. | 2011 | Plant Cell Environ. | pmid:21443577 |
Zhang B et al. | A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. | 2011 | Biochemistry | pmid:21438569 |
Henneman L et al. | Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS. | 2011 | Biochim. Biophys. Acta | pmid:21237288 |
Kim RH et al. | Bisphosphonates induce senescence in normal human oral keratinocytes. | 2011 | J. Dent. Res. | pmid:21427353 |
Kyathanahalli CN and Kowluru A | A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGEâ‚‚. | 2011 | Biochem. Pharmacol. | pmid:21406184 |
Zhao Y et al. | Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. | 2011 | J. Invest. Dermatol. | pmid:21390048 |
Blankier S et al. | The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease. | 2011 | Clin. Exp. Immunol. | pmid:21361911 |
Ghavami S et al. | Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. | 2011 | PLoS ONE | pmid:21304979 |
Ignea C et al. | Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. | 2011 | Microb. Cell Fact. | pmid:21276210 |
Cluis CP et al. | Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). | 2011 | Metab. Eng. | pmid:21986057 |
Relja B et al. | Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK. | 2011 | Int. J. Oncol. | pmid:21206971 |
Liu Q et al. | Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. | 2011 | PLoS ONE | pmid:21858047 |
Kimachi K et al. | Zoledronic acid inhibits RANK expression and migration of osteoclast precursors during osteoclastogenesis. | 2011 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:21225243 |
Epplen R et al. | Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. | 2011 | Acta Oncol | pmid:20429730 |
Jouneau S et al. | Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. | 2011 | PLoS ONE | pmid:21826199 |
Zhong WB et al. | Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. | 2011 | Biochem. Pharmacol. | pmid:21907187 |
Zeki AA et al. | Statin drugs, metabolic pathways, and asthma: a therapeutic opportunity needing further research. | 2011 | Drug Metab Lett | pmid:21198438 |
Llacuna L et al. | Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia-reperfusion injury. | 2011 | J. Hepatol. | pmid:21145825 |
Hamada M et al. | Antithrombotic properties of pravastatin reducing intra-thrombus fibrin deposition under high shear blood flow conditions. | 2011 | Thromb. Haemost. | pmid:21136018 |
Hao Q et al. | Synthesis and anti-hypercholesterolemic evaluations of calcium salts of 4-substituted quinoline-based mevalonic acid. | 2011 | Chem Biol Drug Des | pmid:21791012 |
Esemuede N et al. | Lovastatin inhibits thrombospondin-1-induced smooth muscle cell chemotaxis. | 2011 | J. Surg. Res. | pmid:20338582 |
Soto G et al. | Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation. | 2011 | J. Exp. Bot. | pmid:21908473 |
Wong DH et al. | Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells. | 2011 | Fertil. Steril. | pmid:21907337 |
Jang HJ et al. | Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. | 2011 | Microb. Cell Fact. | pmid:21801353 |
Schaafsma D et al. | Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. | 2011 | Respir. Res. | pmid:21864337 |
Kaneko M et al. | Effect of farnesol on mevalonate pathway of Staphylococcus aureus. | 2011 | J. Antibiot. | pmid:21772307 |
Yanae M et al. | Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. | 2011 | J. Exp. Clin. Cancer Res. | pmid:21831290 |