Okin D and Medzhitov R |
The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia. |
2016 |
Cell |
pmid:26997483
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Salunkhe VA et al. |
Rosuvastatin Treatment Affects Both Basal and Glucose-Induced Insulin Secretion in INS-1 832/13 Cells. |
2016 |
PLoS ONE |
pmid:26986474
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Marcuzzi A et al. |
Geranylgeraniol and Neurological Impairment: Involvement of Apoptosis and Mitochondrial Morphology. |
2016 |
Int J Mol Sci |
pmid:26978350
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Yildirim FI et al. |
Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. |
2015 |
Prostaglandins Other Lipid Mediat. |
pmid:26201058
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Surup F et al. |
Deconins A-E: Cuparenic and Mevalonic or Propionic Acid Conjugates from the Basidiomycete Deconica sp. 471. |
2015 |
J. Nat. Prod. |
pmid:25871540
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York AG et al. |
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. |
2015 |
Cell |
pmid:26686653
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Miettinen TP and Björklund M |
Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy. |
2015 |
Cell Rep |
pmid:26686643
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Gallagher KA and Jensen PR |
Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade. |
2015 |
BMC Genomics |
pmid:26578069
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Nyati P et al. |
Negative Feedbacks by Isoprenoids on a Mevalonate Kinase Expressed in the Corpora Allata of Mosquitoes. |
2015 |
PLoS ONE |
pmid:26566274
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Chen Y et al. |
Mevalonate inhibits acid sphingomyelinase activity, increases sphingomyelin levels and inhibits cell proliferation of HepG2 and Caco-2 cells. |
2015 |
Lipids Health Dis |
pmid:26493087
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Laezza C et al. |
p53 regulates the mevalonate pathway in human glioblastoma multiforme. |
2015 |
Cell Death Dis |
pmid:26469958
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Rondini EA et al. |
Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes. |
2015 |
J. Pharmacol. Exp. Ther. |
pmid:26427720
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Guan Z et al. |
Metabolic engineering of Bacillus subtilis for terpenoid production. |
2015 |
Appl. Microbiol. Biotechnol. |
pmid:26373726
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Pandyra AA et al. |
Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death. |
2015 |
Oncotarget |
pmid:26353928
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Kuo KK et al. |
Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss. |
2015 |
J. Lipid Res. |
pmid:26351364
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Kain V et al. |
Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism. |
2015 |
Sci Rep |
pmid:26345110
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Henry LK et al. |
Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26216978
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Zhang Z et al. |
Genomic variations of the mevalonate pathway in porokeratosis. |
2015 |
Elife |
pmid:26202976
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Venkateshwaran M et al. |
A role for the mevalonate pathway in early plant symbiotic signaling. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26199419
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Tricarico PM et al. |
Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link. |
2015 |
Int J Mol Sci |
pmid:26184189
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Kobayashi Y et al. |
Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models. |
2015 |
Clin. Cancer Res. |
pmid:26109099
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Tricarico PM et al. |
Alendronate, a double-edged sword acting in the mevalonate pathway. |
2015 |
Mol Med Rep |
pmid:26096667
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Hofberger JA et al. |
Large-Scale Evolutionary Analysis of Genes and Supergene Clusters from Terpenoid Modular Pathways Provides Insights into Metabolic Diversification in Flowering Plants. |
2015 |
PLoS ONE |
pmid:26046541
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Karlic H et al. |
Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells. |
2015 |
Cancer Genet |
pmid:25978957
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Zhou X et al. |
Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation. |
2015 |
Mol Med Rep |
pmid:25936991
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Du X et al. |
Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots. |
2015 |
Molecules |
pmid:25919278
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Chen GP et al. |
Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process. |
2015 |
J Diabetes Res |
pmid:25918730
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Sharon C et al. |
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. |
2015 |
Oncotarget |
pmid:25895029
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Hwang HS et al. |
Transcriptomic analysis of Siberian ginseng (Eleutherococcus senticosus) to discover genes involved in saponin biosynthesis. |
2015 |
BMC Genomics |
pmid:25888223
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Hirota Y et al. |
Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1. |
2015 |
PLoS ONE |
pmid:25874989
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Autefage H et al. |
Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25831522
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Wang WQ et al. |
Proteomic analysis of lettuce seed germination and thermoinhibition by sampling of individual seeds at germination and removal of storage proteins by polyethylene glycol fractionation. |
2015 |
Plant Physiol. |
pmid:25736209
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Sekiya A et al. |
Fluvastatin Upregulates the Expression of Tissue Factor Pathway Inhibitor in Human Umbilical Vein Endothelial Cells. |
2015 |
J. Atheroscler. Thromb. |
pmid:25735397
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Polotskaia A et al. |
Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25733866
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de Oliveira LS et al. |
New Insights on the terpenome of the red seaweed Laurencia dendroidea (Florideophyceae, Rhodophyta). |
2015 |
Mar Drugs |
pmid:25675000
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Rossoni L et al. |
The Putative mevalonate diphosphate decarboxylase from Picrophilus torridus is in reality a mevalonate-3-kinase with high potential for bioproduction of isobutene. |
2015 |
Appl. Environ. Microbiol. |
pmid:25636853
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Skaff DA et al. |
Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds. |
2015 |
Arch. Biochem. Biophys. |
pmid:25499551
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Kang S et al. |
Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. |
2015 |
Eur J Med Chem |
pmid:25461893
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Matsuo S et al. |
Single-dose rosuvastatin ameliorates lung ischemia-reperfusion injury via upregulation of endothelial nitric oxide synthase and inhibition of macrophage infiltration in rats with pulmonary hypertension. |
2015 |
J. Thorac. Cardiovasc. Surg. |
pmid:25454916
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Vinokur JM et al. |
Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. |
2015 |
Protein Sci. |
pmid:25422158
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Greife A et al. |
Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation. |
2015 |
Tumour Biol. |
pmid:25566959
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Burgazli KM et al. |
The impact of statins on FGF-2-stimulated human umbilical vein endothelial cells. |
2014 |
Postgrad Med |
pmid:24393759
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Moise AR et al. |
Mechanistic aspects of carotenoid biosynthesis. |
2014 |
Chem. Rev. |
pmid:24175570
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Jiang P et al. |
In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells. |
2014 |
Br. J. Cancer |
pmid:25093497
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Sivanandhan G et al. |
Enhanced biosynthesis of withanolides by elicitation and precursor feeding in cell suspension culture of Withania somnifera (L.) Dunal in shake-flask culture and bioreactor. |
2014 |
PLoS ONE |
pmid:25089711
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Rastogi S et al. |
De novo sequencing and comparative analysis of holy and sweet basil transcriptomes. |
2014 |
BMC Genomics |
pmid:25015319
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Fabris M et al. |
Tracking the sterol biosynthesis pathway of the diatom Phaeodactylum tricornutum. |
2014 |
New Phytol. |
pmid:24996048
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Pandyra A et al. |
Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop. |
2014 |
Cancer Res. |
pmid:24994712
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Li J et al. |
De novo synthesis of steroids and oxysterols in adipocytes. |
2014 |
J. Biol. Chem. |
pmid:24280213
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González-Caballero N et al. |
Expression of the mevalonate pathway enzymes in the Lutzomyia longipalpis (Diptera: Psychodidae) sex pheromone gland demonstrated by an integrated proteomic approach. |
2014 |
J Proteomics |
pmid:24185139
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