Elsayed M et al. |
Synergistic Antiproliferative Effects of Zoledronic Acid and Fluvastatin on Human Pancreatic Cancer Cell Lines: An in Vitro Study. |
2016 |
Biol. Pharm. Bull. |
pmid:27181081
|
Silva Ramos E et al. |
Bioenergetic roles of mitochondrial fusion. |
2016 |
Biochim. Biophys. Acta |
pmid:27060252
|
Wang T et al. |
Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway. |
2016 |
Oncotarget |
pmid:26565813
|
Yildirim FI et al. |
Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. |
2015 |
Prostaglandins Other Lipid Mediat. |
pmid:26201058
|
Surup F et al. |
Deconins A-E: Cuparenic and Mevalonic or Propionic Acid Conjugates from the Basidiomycete Deconica sp. 471. |
2015 |
J. Nat. Prod. |
pmid:25871540
|
York AG et al. |
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. |
2015 |
Cell |
pmid:26686653
|
Miettinen TP and Björklund M |
Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy. |
2015 |
Cell Rep |
pmid:26686643
|
Gallagher KA and Jensen PR |
Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade. |
2015 |
BMC Genomics |
pmid:26578069
|
Nyati P et al. |
Negative Feedbacks by Isoprenoids on a Mevalonate Kinase Expressed in the Corpora Allata of Mosquitoes. |
2015 |
PLoS ONE |
pmid:26566274
|
Chen Y et al. |
Mevalonate inhibits acid sphingomyelinase activity, increases sphingomyelin levels and inhibits cell proliferation of HepG2 and Caco-2 cells. |
2015 |
Lipids Health Dis |
pmid:26493087
|
Laezza C et al. |
p53 regulates the mevalonate pathway in human glioblastoma multiforme. |
2015 |
Cell Death Dis |
pmid:26469958
|
Rondini EA et al. |
Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes. |
2015 |
J. Pharmacol. Exp. Ther. |
pmid:26427720
|
Guan Z et al. |
Metabolic engineering of Bacillus subtilis for terpenoid production. |
2015 |
Appl. Microbiol. Biotechnol. |
pmid:26373726
|
Pandyra AA et al. |
Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death. |
2015 |
Oncotarget |
pmid:26353928
|
Kuo KK et al. |
Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss. |
2015 |
J. Lipid Res. |
pmid:26351364
|
Kain V et al. |
Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism. |
2015 |
Sci Rep |
pmid:26345110
|
Henry LK et al. |
Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26216978
|
Zhang Z et al. |
Genomic variations of the mevalonate pathway in porokeratosis. |
2015 |
Elife |
pmid:26202976
|
Venkateshwaran M et al. |
A role for the mevalonate pathway in early plant symbiotic signaling. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26199419
|
Tricarico PM et al. |
Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link. |
2015 |
Int J Mol Sci |
pmid:26184189
|
Kobayashi Y et al. |
Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models. |
2015 |
Clin. Cancer Res. |
pmid:26109099
|
Tricarico PM et al. |
Alendronate, a double-edged sword acting in the mevalonate pathway. |
2015 |
Mol Med Rep |
pmid:26096667
|
Hofberger JA et al. |
Large-Scale Evolutionary Analysis of Genes and Supergene Clusters from Terpenoid Modular Pathways Provides Insights into Metabolic Diversification in Flowering Plants. |
2015 |
PLoS ONE |
pmid:26046541
|
Karlic H et al. |
Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells. |
2015 |
Cancer Genet |
pmid:25978957
|
Zhou X et al. |
Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation. |
2015 |
Mol Med Rep |
pmid:25936991
|
Du X et al. |
Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots. |
2015 |
Molecules |
pmid:25919278
|
Chen GP et al. |
Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process. |
2015 |
J Diabetes Res |
pmid:25918730
|
Sharon C et al. |
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. |
2015 |
Oncotarget |
pmid:25895029
|
Hwang HS et al. |
Transcriptomic analysis of Siberian ginseng (Eleutherococcus senticosus) to discover genes involved in saponin biosynthesis. |
2015 |
BMC Genomics |
pmid:25888223
|
Hirota Y et al. |
Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1. |
2015 |
PLoS ONE |
pmid:25874989
|
Autefage H et al. |
Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25831522
|
Wang WQ et al. |
Proteomic analysis of lettuce seed germination and thermoinhibition by sampling of individual seeds at germination and removal of storage proteins by polyethylene glycol fractionation. |
2015 |
Plant Physiol. |
pmid:25736209
|
Sekiya A et al. |
Fluvastatin Upregulates the Expression of Tissue Factor Pathway Inhibitor in Human Umbilical Vein Endothelial Cells. |
2015 |
J. Atheroscler. Thromb. |
pmid:25735397
|
Polotskaia A et al. |
Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25733866
|
de Oliveira LS et al. |
New Insights on the terpenome of the red seaweed Laurencia dendroidea (Florideophyceae, Rhodophyta). |
2015 |
Mar Drugs |
pmid:25675000
|
Rossoni L et al. |
The Putative mevalonate diphosphate decarboxylase from Picrophilus torridus is in reality a mevalonate-3-kinase with high potential for bioproduction of isobutene. |
2015 |
Appl. Environ. Microbiol. |
pmid:25636853
|
Skaff DA et al. |
Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds. |
2015 |
Arch. Biochem. Biophys. |
pmid:25499551
|
Kang S et al. |
Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. |
2015 |
Eur J Med Chem |
pmid:25461893
|
Matsuo S et al. |
Single-dose rosuvastatin ameliorates lung ischemia-reperfusion injury via upregulation of endothelial nitric oxide synthase and inhibition of macrophage infiltration in rats with pulmonary hypertension. |
2015 |
J. Thorac. Cardiovasc. Surg. |
pmid:25454916
|
Vinokur JM et al. |
Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. |
2015 |
Protein Sci. |
pmid:25422158
|
Greife A et al. |
Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation. |
2015 |
Tumour Biol. |
pmid:25566959
|
Sorrentino G et al. |
Metabolic control of YAP and TAZ by the mevalonate pathway. |
2014 |
Nat. Cell Biol. |
pmid:24658687
|
Al-Haidari AA et al. |
HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24582560
|
Huchelmann A et al. |
S-carvone suppresses cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation. |
2014 |
Plant Physiol. |
pmid:24367019
|
Larson-Casey JL et al. |
Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis. |
2014 |
J. Biol. Chem. |
pmid:25378391
|
Shimabukuro-Vornhagen A et al. |
Inhibition of protein geranylgeranylation specifically interferes with CD40-dependent B cell activation, resulting in a reduced capacity to induce T cell immunity. |
2014 |
J. Immunol. |
pmid:25311809
|
Chang TI et al. |
The effect of statin on epithelial-mesenchymal transition in peritoneal mesothelial cells. |
2014 |
PLoS ONE |
pmid:25275561
|
Kanugula AK et al. |
Fluvastatin mediated breast cancer cell death: a proteomic approach to identify differentially regulated proteins in MDA-MB-231 cells. |
2014 |
PLoS ONE |
pmid:25268751
|
Vannice JC et al. |
Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway. |
2014 |
J. Bacteriol. |
pmid:24375100
|
Wang Z et al. |
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24367099
|