| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypergammaglobulinemia | D006942 | 9 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ogunwobi OO and Beales IL | Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. | 2008 | Am. J. Gastroenterol. | pmid:18371146 |
| Kotti T et al. | Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18685105 |
| Rekittke I et al. | Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. | 2008 | J. Am. Chem. Soc. | pmid:19035630 |
| Saito E et al. | 7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells. | 2008 | J. Atheroscler. Thromb. | pmid:18603819 |
| Grigore L et al. | Combination therapy in cholesterol reduction: focus on ezetimibe and statins. | 2008 | Vasc Health Risk Manag | pmid:18561502 |
| Sharyo S et al. | Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. | 2008 | Kidney Int. | pmid:18509318 |
| Kervizic G and Corcos L | Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. | 2008 | BMC Syst Biol | pmid:19025648 |
| Udagawa H et al. | Increase of serum cholesterol levels by heat-moisture-treated high-amylose cornstarch in rats fed a high-cholesterol diet. | 2008 | Lipids | pmid:18509689 |
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| Cornish J et al. | Modulation of osteoclastogenesis by fatty acids. | 2008 | Endocrinology | pmid:18617622 |
| Okada K et al. | Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | 2008 | Plant Cell Physiol. | pmid:18303110 |
| Lüdke SM et al. | Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 2008 | J. Lipid Res. | pmid:18669481 |
| Carrasco MP et al. | Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells. | 2008 | FEBS J. | pmid:18312412 |
| Winiarska M et al. | Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. | 2008 | PLoS Med. | pmid:18366248 |
| Oliveira KA et al. | Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction. | 2008 | J. Bioenerg. Biomembr. | pmid:18679777 |
| Chana RS et al. | Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis. | 2008 | Am. J. Nephrol. | pmid:18535368 |
| Abumweis SS et al. | Plant sterols/stanols as cholesterol lowering agents: A meta-analysis of randomized controlled trials. | 2008 | Food Nutr Res | pmid:19109655 |
| Sapir-Mir M et al. | Peroxisomal localization of Arabidopsis isopentenyl diphosphate isomerases suggests that part of the plant isoprenoid mevalonic acid pathway is compartmentalized to peroxisomes. | 2008 | Plant Physiol. | pmid:18988695 |
| Sławińska A and Kandefer-Szerszeń M | [The anticancer properties of statins]. | 2008 | Postepy Hig Med Dosw (Online) | pmid:18688209 |
| Acharjee S and Welty FK | Atorvastatin and cardiovascular risk in the elderly--patient considerations. | 2008 | Clin Interv Aging | pmid:18686752 |
| Journe F et al. | Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. | 2008 | Breast Cancer Res. Treat. | pmid:17333335 |
| Sando T et al. | Cloning and characterization of mevalonate pathway genes in a natural rubber producing plant, Hevea brasiliensis. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18685207 |
| Laezza C et al. | The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. | 2008 | Endocr. Relat. Cancer | pmid:18676619 |
| Bate C et al. | Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. | 2008 | BMC Biol. | pmid:18789130 |
| Kistowska M et al. | Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells. | 2008 | Eur. J. Immunol. | pmid:18624305 |
| Matsuda T et al. | Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18593956 |
| Habara K et al. | Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. | 2008 | Nitric Oxide | pmid:17936042 |
| Fried LF | Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease. | 2008 | Kidney Int. | pmid:18528321 |
| Skorupinska-Tudek K et al. | Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. | 2008 | J. Biol. Chem. | pmid:18502754 |
| Zhang X et al. | Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. | 2008 | J. Immunol. | pmid:18453621 |
| Aprigliano I et al. | Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. | 2008 | Liver Int. | pmid:18339080 |
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| Burke LP and Kukoly CA | Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours. | 2008 | Leuk. Lymphoma | pmid:18231920 |
| Glynn SA et al. | The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. | 2008 | BMC Cancer | pmid:18199328 |
| Galichet A et al. | Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. | 2008 | Plant Physiol. | pmid:18184738 |
| Kodaman PH and Duleba AJ | Statins in the treatment of polycystic ovary syndrome. | 2008 | Semin. Reprod. Med. | pmid:18181091 |
| Baba TT et al. | Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. | 2008 | J. Muscle Res. Cell. Motil. | pmid:18792797 |
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| Osman L et al. | Atorvastatin accelerates extracellular nucleotide degradation in human endothelial cells. | 2008 | Mol. Cell. Biochem. | pmid:18158588 |
| Paintlia AS et al. | Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. | 2008 | Mol. Pharmacol. | pmid:18239032 |
| Martin-Ventura JL et al. | LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin. | 2008 | Atherosclerosis | pmid:18378243 |
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| Begley M et al. | Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection. | 2008 | Infect. Immun. | pmid:18765739 |
| Simonen M et al. | High-content assay to study protein prenylation. | 2008 | J Biomol Screen | pmid:18509097 |
| Tarhzaoui K et al. | Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetes. | 2008 | Diabetes Res. Clin. Pract. | pmid:18406000 |
| Kaliszewski P et al. | Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae. | 2008 | Biochim. Biophys. Acta | pmid:18771750 |
| Voynova NE et al. | Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. | 2008 | Arch. Biochem. Biophys. | pmid:18823933 |
| Pscheidt B and Glieder A | Yeast cell factories for fine chemical and API production. | 2008 | Microb. Cell Fact. | pmid:18684335 |
| Schwartz YSh et al. | Cholesterol-induced stimulation of postinflammatory liver fibrosis. | 2008 | Bull. Exp. Biol. Med. | pmid:19110552 |
| Liang YJ et al. | Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products. | 2008 | Cardiology | pmid:18057884 |
| Yu F et al. | Isolation and functional characterization of a beta-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith. | 2008 | FEBS Lett. | pmid:18242187 |
| de Ruyck J and Wouters J | Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. | 2008 | Curr. Protein Pept. Sci. | pmid:18393884 |
| Lazzerini PE et al. | Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. | 2007 Sep-Oct | Clin. Exp. Rheumatol. | pmid:18078616 |
| Yoon SH et al. | Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. | 2007 May-Jun | Biotechnol. Prog. | pmid:17500531 |
| Matsunaga S et al. | Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells. | 2007 Mar-Apr | Anticancer Res. | pmid:17465222 |
| Bock O et al. | Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. | 2007 Apr-Jun | J Musculoskelet Neuronal Interact | pmid:17627083 |
| Yoon SH et al. | Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115209 |
| Ye J | Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus. | 2007 | PLoS Pathog. | pmid:17784784 |
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| Saijonmaa O et al. | Atorvastatin inhibits angiotensin-converting enzyme induction in differentiating human macrophages. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17158648 |
| Nishimoto T et al. | Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17599378 |
| Honda A et al. | Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS. | 2007 | J. Lipid Res. | pmid:17272831 |
| Sarrabayrouse G et al. | Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells. | 2007 | Neoplasia | pmid:18084615 |
| Bretón MartÃnez JR et al. | Mevalonic aciduria: report of two cases. | 2007 | J. Inherit. Metab. Dis. | pmid:17578678 |
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| Haas D and Hoffmann GF | Mevalonate kinase deficiency and autoinflammatory disorders. | 2007 | N. Engl. J. Med. | pmid:17596600 |
| Hargreaves IP | Coenzyme Q10 in phenylketonuria and mevalonic aciduria. | 2007 | Mitochondrion | pmid:17442628 |
| Ferri N et al. | Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17303772 |
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| Hamadmad SN and Hohl RJ | Lovastatin suppresses erythropoietin receptor surface expression through dual inhibition of glycosylation and geranylgeranylation. | 2007 | Biochem. Pharmacol. | pmid:17586475 |
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| Arkwright PD et al. | Mevalonic aciduria cured by bone marrow transplantation. | 2007 | N. Engl. J. Med. | pmid:17898110 |
| Zeiser R et al. | Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity. | 2007 | Blood | pmid:17827390 |
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| Ostrowski SM et al. | Statins reduce amyloid-beta production through inhibition of protein isoprenylation. | 2007 | J. Biol. Chem. | pmid:17646164 |
| Hu WL et al. | Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin. | 2007 | Cytokine | pmid:18023360 |
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| Wong J et al. | Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol. | 2007 | Lipids Health Dis | pmid:17408498 |
| Lopes AA et al. | Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). | 2007 | Phytochemistry | pmid:17574633 |
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