Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Kandutsch AA and Hancock RL | Regulation of the rate of sterol synthesis and the level of beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in mouse liver and hepatomas. | 1971 | Cancer Res. | pmid:4328734 |
Hornby GM and Boyd GS | The origin of lanosta-7,24-dienol in rat skin. | 1971 | Biochem. J. | pmid:5131739 |
Richards JB et al. | Dolichol phosphates as acceptors of mannose from guanosine diphosphate mannose in liver systems. | 1971 | Biochem. J. | pmid:5131017 |
Yamasaki K et al. | Isolation of 3 7 -dihydroxychol-5-en-24-oic acid, an intermediate of chenodeoxycholic acid biogenesis, from fistula bile of the rat and hen. | 1971 | J. Biochem. | pmid:5134665 |
McNamara DJ et al. | Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. Developmental pattern. | 1972 | J. Biol. Chem. | pmid:5057084 |
Williams CD and Avigan J | In vitro effects of serum proteins and lipids on lipid synthesis in human skin fibroblasts and leukocytes grown in culture. | 1972 | Biochim. Biophys. Acta | pmid:4338876 |
Edgren B and Hellström K | Lipid biosynthesis from DL (2- 14 C) mevalonic acid in intact mice and rabbits. | 1972 | Acta Physiol. Scand. | pmid:4640173 |
Cuzzopoli M et al. | Effect of nephrectomy and cholesterol feeding on the metabolism of intravenously administered DL-mevalonate in the rat. | 1972 | Metab. Clin. Exp. | pmid:4641957 |
Mak KM and Trier JS | Radioautographic and chemical evidence for (5- 3 H)mevalonate incorporation into cholesterol by rat villous absorptive cells. | 1972 | Biochim. Biophys. Acta | pmid:4642214 |
Richards JB and Hemming FW | Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. | 1972 | Biochem. J. | pmid:4643705 |
Hickman PE et al. | Effect of adrenalectomy on the diurnal variation of hepatic cholesterogenesis in the rat. | 1972 | J. Lipid Res. | pmid:5059193 |
Lefevre AF et al. | Effect of ethanol on cholesterol and bile acid metabolism. | 1972 | J. Lipid Res. | pmid:5059198 |
Salen G and Polito A | Biosynthesis of 5 -cholestan-3 -ol in cerebrotendinous xanthomatosis. | 1972 | J. Clin. Invest. | pmid:4550120 |
Aiyar AS and Olson RE | Enhancement of ubiquinone-9 biosynthesis in rat-liver slices by exogenous mevalonate. | 1972 | Eur. J. Biochem. | pmid:4340277 |
Sharma RK et al. | Steroidogenesis in isolated adrenal cells of rat. 3. Morphological and biochemical correlation of cholesterol and cholesterol ester content in ACTH and N6-2'-O-dibutyryl-adenosine-3',5'-monophosphate activated adrenal cells. | 1972 | Endocrinology | pmid:4340613 |
Gaskin F and Clayton RB | An interstrain difference in cholesterol synthesis in vitro in mice, dependent upon a difference in endogenous NADPH-generating capacity. | 1972 | J. Lipid Res. | pmid:4400581 |
White LW | Feedback regulation of cholesterol biosynthesis: studies with cholestyramine. | 1972 | Circ. Res. | pmid:4641786 |
Walton MJ and Pennock JF | Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. | 1972 | Biochem. J. | pmid:4403925 |
Green TR and Baisted DJ | Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination. | 1972 | Biochem. J. | pmid:4348263 |
Beg ZH and Lupien PJ | In vitro and in vivo inhibition of hepatic cholesterol synthesis by 3-hydroxy-3-methylglutaric acid. | 1972 | Biochim. Biophys. Acta | pmid:5061662 |
Gaskin F and Clayton RB | Decreased availability of hepatic NADPH in stressed mice. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4400445 |
Craig MC et al. | Comparative effects of dietary regimens on the levels of enzymes regulating the synthesis of fatty acids and cholesterol in rat liver. | 1972 | Arch. Biochem. Biophys. | pmid:5044513 |
Jayaram M and Raman TS | Metabolism of ergosterol in the larva of the rice moth (Corcyra cephalonica St.). | 1972 | Biochem. J. | pmid:5085614 |
Shefer S et al. | Diurnal variation of HMG CoA reductase activity in rat intestine. | 1972 | J. Lipid Res. | pmid:5075502 |
Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. Distribution in subcellular fractions as a function of time after intracerebral injection into developing brain of (2- 14 C)mevalonic. | 1972 | J. Neurochem. | pmid:5009889 |
Gibbons GF and Mitropoulos KA | Inhibition of cholesterol biosynthesis by carbon monoxide: accumulation of lanosterol and 24,25-dihydrolanosterol. | 1972 | Biochem. J. | pmid:5073750 |
Ramsey RB et al. | Formation of methyl sterols in brain cholesterol biosynthesis. Sterol formation in vitro in actively myelinating rat brain. | 1972 | J. Biol. Chem. | pmid:5030627 |
Rao GS and Ramasarma T | ATP in the regulation of cholesterol biosynthesis- a supra-energetic role. | 1972 | Biochem. Biophys. Res. Commun. | pmid:5077855 |
Gregory KW et al. | Diurnal variations in rat liver 3-hydroxy-3-methylglutaryl-Coenzyme A reductase activity in relation to feeding. | 1972 | Biochem. J. | pmid:4656802 |
Robbers JE et al. | Physiological studies on ergot: further studies on the induction of alkaloid synthesis by tryptophan and its inhibition by phosphate. | 1972 | J. Bacteriol. | pmid:5086659 |
Avigan J et al. | In vitro biosynthesis of lipids, proteins and deoxyribonucleic acid in aortic tissue and in culture aortic cells. | 1972 | Biochim. Biophys. Acta | pmid:5041430 |
Goldfarb S and Pitot HC | Stimulatory effect of dietary lipid and cholestyramine on hepatic HMG CoA reductase. | 1972 | J. Lipid Res. | pmid:4641420 |
Ray PH et al. | Consequences of glycerol deprivation on the synthesis of membrane components in a glycerol auxotroph of Staphylococcus aureus. | 1972 | J. Bacteriol. | pmid:5079070 |
Goodwin TW | Recent developments in the study of the biosynthesis of carotenoids. | 1972 | Biochem. J. | pmid:5085548 |
Nomura S et al. | Inhibition of sterol and fatty acid biosyntheses by cerulenin in cell-free systems of yeast. | 1972 | J. Antibiot. | pmid:4568013 |
Trumpower BL et al. | Studies on ubiquinone. The isolation and identification of 5-demethoxyubiquinone-9 as an intermediate in biosynthesis of ubiquinone-9 in the rat. | 1972 | J. Biol. Chem. | pmid:4553441 |
Durr IF and Habbal MZ | The biosynthesis of C 55 polyprenols by a cell-free preparation of Lactobacillus plantarum. | 1972 | Biochem. J. | pmid:5076663 |
Thorne KJ and Barker DC | The occurrence of bactoprenol in the mesosome and plasma membranes of Lactobacillus casei and Lactobacillus plantarum. | 1972 | J. Gen. Microbiol. | pmid:4625239 |
Hardman R and Fazli FR | Labelled steroidal sapogenins and hydrocarbons from Trigonella foenumgraecum by acetate, mevalonate and cholesterol feeds to seeds. | 1972 | Planta Med. | pmid:5018497 |
Momose K and Rudney H | 3-Polyprenyl-4-hydroxybenzoate synthesis in the inner membrane of mitochondria from p-hydroxybenzoate and isopentenylpyrophosphate. A demonstration of isoprenoid synthesis in rat liver mitochondria. | 1972 | J. Biol. Chem. | pmid:4338233 |
Slakey LL et al. | The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. | 1972 | J. Biol. Chem. | pmid:4337504 |
Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
Malhotra HC and Nes WR | The conversion of mevalonate to 24-methylenecycloartanol by a cell-free enzyme preparation from nonphotosynthetic tissue. | 1972 | J. Biol. Chem. | pmid:4651646 |
Heintz R et al. | Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4344813 |
Atkin SD et al. | The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. | 1972 | Biochem. J. | pmid:4655417 |
Barr RM and Hemming FW | Polyprenol phosphate as an acceptor of mannose from guanosine diphosphate mannose in Aspergillus niger. | 1972 | Biochem. J. | pmid:5073732 |
Prottey C et al. | Lipid synthesis in rat skin. | 1972 | Br. J. Dermatol. | pmid:4648803 |
Atkin SD et al. | The role of cytochrome P-450 in cholesterol biogenesis and catabolism. | 1972 | Biochem. J. | pmid:5084788 |
Lehner ND et al. | Effects of insulin deficiency, hypothyroidism, and hypertension on cholesterol metabolism in the squirrel monkey. | 1972 | Exp. Mol. Pathol. | pmid:4622478 |
Rodwell VW | Cholesterol regulation of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1972 | Biochem. J. | pmid:5085556 |
Kandutsch AA and Saucier SE | Sterol and fatty acid synthesis in developing brains of three myelin-deficient mouse mutants. | 1972 | Biochim. Biophys. Acta | pmid:5012453 |
Rose HG | Origin of cholesteryl esters in the blood of cholesterolfed rabbits: relative contributions of serum lecithin-cholesterol acyltransferase and hepatic ester synthesis. | 1972 | Biochim. Biophys. Acta | pmid:5012982 |
Jedlicki E et al. | Stereospecificity of isopentenylpyrophosphate isomerase and prenyl transferase from pinus and citrus. | 1972 | Arch. Biochem. Biophys. | pmid:4635785 |
Milborrow BV | Stereochemical aspects of the formation of double bonds in abscisic acid. | 1972 | Biochem. J. | pmid:4643698 |
Madyastha KM et al. | Carboxyl group methylation of loganic acid by a cell-free enzyme preparation from Vinca rosea. | 1972 | Biochem. J. | pmid:4404427 |
Logan DM | Thermal and pH stability of 2 -isopentenyl pyrophosphate. | 1972 | J. Lipid Res. | pmid:4333821 |
Beedle AS et al. | The stereochemistry of hydrogen transfer from NADPH catalysed by 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. | 1972 | Eur. J. Biochem. | pmid:4403574 |
Banthorpe DV et al. | Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium graveolens and Rosa dilecta. | 1972 | Biochem. J. | pmid:4348258 |
Beedle AS et al. | The stereochemistry of the reduction of mevaldic acid-coenzyme A hemithioacetal by rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1972 | FEBS Lett. | pmid:4405222 |
Ayaki Y and Yamasaki | Identification of 3 , 7 -dihydroxychol-5-enoic acid in fistula bile of the rat given cholesterol-4- 14 C and DL-mevalonate-2- 14 C. | 1972 | J. Biochem. | pmid:5015370 |
Barr RM and Hemming FW | Polyprenols of Aspergillus niger. Their characterization, biosynthesis and subcellular distribution. | 1972 | Biochem. J. | pmid:5073731 |
Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. Distribution in subcellular fractions as a function of time after intracerebral injection of (2- 14 C)mevalonic acid into 30-day-old rat brain: a period of transition. | 1972 | J. Neurochem. | pmid:5019590 |
Miettinen TA | Mode of action of a new hypocholesteraemic drug (DH-581) in familial hypercholesteraemia. | 1972 Mar-Apr | Atherosclerosis | pmid:4666121 |
Thorne KJ | Identification of prenol intermediates of wall biosynthesis in growing cells of Lactobacillus plantarum. | 1973 | J. Bacteriol. | pmid:4745415 |
Grigor MR et al. | Cholesterol metabolism in rats bearing Morris hepatoma 7777. | 1973 | Cancer Res. | pmid:4352741 |
Bortz WM | On the control of cholesterol synthesis. | 1973 | Metab. Clin. Exp. | pmid:4206254 |
Bojesen E et al. | Sterol biosynthesis in vitro of rat renal inner medulla. | 1973 | Biochim. Biophys. Acta | pmid:4713153 |
Bhavnani BR and Short RV | Formation of steroids by the pregnant mare. IV. Metabolism of 14 C-mevalonic acid and 3 H-dehydroisoandrosterone injected into the fetal circulation. | 1973 | Endocrinology | pmid:4266621 |
Hellstrom KH et al. | Studies of the in vivo metabolism of mevalonic acid in the normal rat. | 1973 | J. Clin. Invest. | pmid:4703220 |
Slakey LL et al. | Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. | 1973 | J. Lipid Res. | pmid:4351784 |
Derksen A and Cohen P | Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro. | 1973 | J. Biol. Chem. | pmid:4355579 |
Bojesen I and Roepstorff P | Identification of C sterols produced by rat renal inner medulla in vitro. | 1973 | Biochim. Biophys. Acta | pmid:4722467 |
Goldstein JL and Brown MS | Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. | 1973 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4355366 |
Shimizu I et al. | Mevalonate synthesis in the mitochondria of yeast. | 1973 | Biochim. Biophys. Acta | pmid:4569545 |
Sérougne-Gautheron C and Chevallier F | Time course of biosynthetic cholesterol in the adult rat brain. | 1973 | Biochim. Biophys. Acta | pmid:4741912 |
Higgins MJ and Kekwick RG | An investigation into the role of malonyl-coenzyme A in isoprenoid biosynthesis. | 1973 | Biochem. J. | pmid:4579226 |
Gibbons GF and Mitropoulos KA | The effect of carbon monoxide on the nature of the accumulated 4,4-dimethyl sterol precursors of cholesterol during its biosynthesis from (2-14C)mevalonic acid in vitro. | 1973 | Biochem. J. | pmid:4724584 |
Kabara JJ | A critical review of brain cholesterol metabolism. | 1973 | Prog. Brain Res. | pmid:4608424 |
Hulcher FH and Oleson WH | Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A. | 1973 | J. Lipid Res. | pmid:4147523 |
Moshier SE and Chapman DJ | Biosynthetic studies on aromatic carotenoids. Biosynthesis of chlorobactene. | 1973 | Biochem. J. | pmid:4774401 |
McDermott JC et al. | Carotenoid biosynthesis in a Flavobacterium sp.: stereochemistry of hydrogen elimination in the desaturation of phytoene to lycopene, rubixanthin and zeaxanthin. | 1973 | Biochem. J. | pmid:4762756 |
Myant NB et al. | Turnover of cholesteryl esters in plasma low-density and high-density lipoproteins in familial hyperbetalipoproteinaemia. | 1973 | Clin Sci Mol Med | pmid:4356485 |
Ranganathan S and Ramasarma T | Inhibition of the biosynthesis of sterols by phenyl and phenolic compounds in rat liver. | 1973 | Biochem. J. | pmid:4749274 |
Ahmad N and Siddiqi M | Bacterial metabolism of 3-hydroxy-3-methylglutaric acid. | 1973 | J. Bacteriol. | pmid:4717513 |
Gray JC and Kekwick RG | Mevalonate kinase in green leaves and etiolated cotyledons of the french bean Phaseolus vulgaris. | 1973 | Biochem. J. | pmid:4723778 |
Bassett RA et al. | Biosynthesis of ergotamine by Claviceps purpurea (Fr.) Tul. | 1973 | Biochem. J. | pmid:4723222 |
Goodwin CD and Margolis S | Specific activation of in vitro cholesterol biosynthesis by preincubation of rat liver homogenates. | 1973 | J. Biol. Chem. | pmid:4745786 |
Brown MS et al. | 3-Hydroxy-3-methylglutaryl coenzyme A reductase. Solubilization and purification of a cold-sensitive microsomal enzyme. | 1973 | J. Biol. Chem. | pmid:4146267 |
Ness GC et al. | Stimulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in hypophysectomized rats by L-triiodothyronine. | 1973 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4521209 |
Kandutsch AA and Chen HW | Inhibition of sterol synthesis in cultured mouse cells by 7alpha-hydroxycholesterol, 7beta-hydroxycholesterol, and 7-ketocholesterol. | 1973 | J. Biol. Chem. | pmid:4797016 |
Kawaguchi A et al. | Subcellular distribution of sesterterpene- and sterol-biosynthesizing activities in Cochliobolus heterostrophus. | 1973 | Biochim. Biophys. Acta | pmid:4120185 |
Merry AH et al. | Oestrogen-stimulated cholesterol and lipid synthesis in Xenopus laevis liver. | 1973 | Biochem. Soc. Trans. | pmid:4802550 |
McIntyre N and Isselbacher KJ | Role of the small intestine in cholesterol metabolism. | 1973 | Am. J. Clin. Nutr. | pmid:4350610 |
Edwards PA | Effect of adrenalectomy and hypophysectomy on the circadian rhythm of -hydroxy- -methylglutaryl coenzyme A reductase activity in rat liver. | 1973 | J. Biol. Chem. | pmid:4697401 |
Thorne KJ | Incorporation of radioactive mevalonate into C50 and C55 phenols by Streptococcus mutans. | 1973 | Biochem. J. | pmid:4772282 |
Sodhi HS and Kudchodkar BJ | Synthesis of cholesterol in hypercholesterolemia and its relationship to plasma trigylcerides. | 1973 | Metab. Clin. Exp. | pmid:4351067 |
Collignon-Thiennot F et al. | [Demonstration of 2 pathways for cholesterol synthesis in the mollusk: patella Patella vulgata L., (Gasteropoda, Prosobranches, Archeogasteropoda)]. | 1973 | Biochimie | pmid:4754188 |
Sodhi HS et al. | Hypocholesterolemic agents and mobilization of tissue cholesterol in man. | 1973 Jan-Feb | Atherosclerosis | pmid:4696743 |
Sodhi HS et al. | Separate pools for endogenous and exogenous cholesterol in rat intestines. | 1973 Mar-Apr | Atherosclerosis | pmid:4709120 |
Heller RA and Gould RG | Reversible cold inactivation of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase from rat liver. | 1974 | J. Biol. Chem. | pmid:4854147 |