Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Wani TA et al. | The effects of rosuvastatin on the serum cortisol, serum lipid, and serum mevalonic acid levels in the healthy Indian male population. | 2010 | AAPS PharmSciTech | pmid:20300897 |
Björkhem-Bergman L et al. | Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. | 2010 | Anticancer Res. | pmid:20530415 |
Morrone D et al. | Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19777230 |
Wang C et al. | Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. | 2010 | Biotechnol. Bioeng. | pmid:20552672 |
Deichmann R et al. | Coenzyme q10 and statin-induced mitochondrial dysfunction. | 2010 | Ochsner J | pmid:21603349 |
Honour JW | Steroid assays in paediatric endocrinology. | 2010 | J Clin Res Pediatr Endocrinol | pmid:21274330 |
Head BP et al. | Loss of caveolin-1 accelerates neurodegeneration and aging. | 2010 | PLoS ONE | pmid:21203469 |
Hamdy RC | Zoledronic acid: clinical utility and patient considerations in osteoporosis and low bone mass. | 2010 | Drug Des Devel Ther | pmid:21151620 |
Stapleton PA et al. | Hypercholesterolemia and microvascular dysfunction: interventional strategies. | 2010 | J Inflamm (Lond) | pmid:21087503 |
Martin DM et al. | Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays. | 2010 | BMC Plant Biol. | pmid:20964856 |
Targett-Adams P et al. | Lipid metabolism and HCV infection. | 2010 | Viruses | pmid:21994676 |
Snoeren TA et al. | The herbivore-induced plant volatile methyl salicylate negatively affects attraction of the parasitoid Diadegma semiclausum. | 2010 | J. Chem. Ecol. | pmid:20407809 |
Lefurgy ST et al. | Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae. | 2010 | J. Biol. Chem. | pmid:20404339 |
Clendening JW et al. | Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma. | 2010 | Blood | pmid:20360469 |
Delang L et al. | Antiviral therapy for hepatitis C virus: beyond the standard of care. | 2010 | Viruses | pmid:21994657 |
Klawitter J et al. | Effects of lovastatin on breast cancer cells: a proteo-metabonomic study. | 2010 | Breast Cancer Res. | pmid:20205716 |
Catros V et al. | [Tgammadelta lymphocytes in oncology: unconventional killer lymphocytes]. | 2010 | Med Sci (Paris) | pmid:20188051 |
Pontillo A et al. | The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency. | 2010 | Eur. J. Hum. Genet. | pmid:20179743 |
Yamauchi N | The pathway of leucine to mevalonate in halophilic archaea: efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20139592 |
Olson AL et al. | NMR dynamics investigation of ligand-induced changes of main and side-chain arginine N-H's in human phosphomevalonate kinase. | 2010 | J. Am. Chem. Soc. | pmid:20112895 |
Yang Z et al. | Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. | 2010 | Int. J. Cancer | pmid:19626588 |
Kowluru A et al. | Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells. | 2010 | Diabetes | pmid:20071600 |
De Leo L et al. | Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches. | 2010 | Pharmacol. Res. | pmid:20206266 |
Kojima Y et al. | Pitavastatin decreases the expression of endothelial lipase both in vitro and in vivo. | 2010 | Cardiovasc. Res. | pmid:20045866 |
Kones R | Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. | 2010 | Drug Des Devel Ther | pmid:21267417 |
Hooff GP et al. | Isoprenoids, small GTPases and Alzheimer's disease. | 2010 | Biochim. Biophys. Acta | pmid:20382260 |
Singh RS et al. | Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston]. | 2010 | BMC Mol. Biol. | pmid:21092138 |
Chang TH et al. | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. | 2010 | Plant Cell | pmid:20139160 |
Quist-Paulsen P | Statins and inflammation: an update. | 2010 | Curr. Opin. Cardiol. | pmid:20421792 |
Kato S et al. | Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase. | 2010 | J. Cell. Mol. Med. | pmid:19432822 |
Hooff GP et al. | Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein production. | 2010 | Mol. Neurobiol. | pmid:20405344 |
Jiang XS et al. | Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency. | 2010 | Mol. Cell Proteomics | pmid:20305089 |
Woo IS et al. | Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. | 2010 | Neurosci. Lett. | pmid:20298756 |
Asadollahi MA et al. | Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. | 2010 | Biotechnol. Bioeng. | pmid:20091767 |
Huang M et al. | Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. | 2010 | Plant Physiol. | pmid:20463089 |
Weerasinghe S and Samantha Dassanayake R | Simulation of structural and functional properties of mevalonate diphosphate decarboxylase (MVD). | 2010 | J Mol Model | pmid:19653015 |
Kudoh T et al. | Mevalonate analogues as substrates of enzymes in the isoprenoid biosynthetic pathway of Streptococcus pneumoniae. | 2010 | Bioorg. Med. Chem. | pmid:20056424 |
Boo KH et al. | Distribution and biosynthesis of 20-hydroxyecdysone in plants of Achyranthes japonica Nakai. | 2010 | Biosci. Biotechnol. Biochem. | pmid:21071854 |
Xu Q et al. | Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. | 2009 | BMC Genomics | pmid:19922663 |
Ledezma E et al. | Potentiated cytotoxic effects of statins and ajoene in murine melanoma cells. | 2009 | Melanoma Res. | pmid:19276863 |
Maeda T and Horiuchi N | Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation. | 2009 | J. Biochem. | pmid:19254925 |
Dje N'Guessan P et al. | Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19122173 |
Jawaid S et al. | Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). | 2009 | PLoS ONE | pmid:20011597 |
Chang PK et al. | Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. | 2009 | Toxins (Basel) | pmid:22069533 |
Kim WY et al. | Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation. | 2009 | J. Neurochem. | pmid:19209406 |
Zeiser R et al. | Regulation of different inflammatory diseases by impacting the mevalonate pathway. | 2009 | Immunology | pmid:19191903 |
Knight LA et al. | Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay. | 2009 | BMC Cancer | pmid:19175937 |
Deshpande G et al. | Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration. | 2009 | PLoS Genet. | pmid:19132091 |
Leszczynska A et al. | Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. | 2009 | PLoS ONE | pmid:20041128 |
Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |