Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Bell FP | Biosynthesis of various sterols, sterol esters, and squalene from [14C]mevalonate by normal swine intima and media in vitro: a comparative study. | 1976 | Exp. Mol. Pathol. | pmid:1001402 |
Takeuchi N et al. | Feed-back control of cholesterol synthesis in partially hepatectomized rats. | 1976 | Biochim. Biophys. Acta | pmid:974156 |
Phillips GT and Clifford KH | Stereochemistry of a methyl-group rearrangement during the biosynthesis of lanosterol. | 1976 | Eur. J. Biochem. | pmid:1245185 |
Endo A et al. | Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1977 | Eur. J. Biochem. | pmid:908337 |
Bernstein BA et al. | Inhibition of cholesterol biosynthesis and acetyl-coenzyme A synthetase by bovine milk and orotic acid. | 1977 | J. Dairy Sci. | pmid:23394 |
Saito Y et al. | Animal cell mutants defective in sterol metabolism: a specific selection procedure and partial characterization of defects. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:269426 |
Faas FH et al. | Unsaturated fatty acyl-CoA inhibition of cholesterol synthesis in vitro. | 1977 | Biochim. Biophys. Acta | pmid:861236 |
Kandutsch AA and Chen HW | Consequences of blocked sterol synthesis in cultured cells. DNA synthesis and membrane composition. | 1977 | J. Biol. Chem. | pmid:833134 |
Wiley MH et al. | The quantitative role of the kidneys in the in vivo metabolism of mevalonate. | 1977 | J. Biol. Chem. | pmid:833143 |
Langdon R et al. | Induction of HMG CoA reductase by the administration of 20,25-diazacholesterol. | 1977 | J. Lipid Res. | pmid:833506 |
Kekki M et al. | Measurement of cholesterol synthesis in kinetically defined pools using fecal steroid analysis and double labeling technique in man. | 1977 | J. Lipid Res. | pmid:833511 |
Sinensky M | Isolation of a mammalian cell mutant resistant to 25-hydroxy cholesterol. | 1977 | Biochem. Biophys. Res. Commun. | pmid:911332 |
Ramsey RB and Fredericks M | Effect of hypocholesterolemic agents on central nervous system cholesterol biosynthesis. II. AY-9944 and AY-9944 plus zuclomiphene. | 1977 | Biochem. Pharmacol. | pmid:70208 |
Fogelman AM et al. | Cholesterol biosynthesis in human lymphocytes, monocytes, and granulocytes. | 1977 | Biochem. Biophys. Res. Commun. | pmid:869944 |
Lakshmanan MR and Veech RL | Measurement of rate of rat liver sterol synthesis in vivo using tritiated water. | 1977 | J. Biol. Chem. | pmid:873910 |
Sliwowski JK et al. | The in vivo biosynthesis of cholesterol from (3RS,2R) [2-14C,2-3H]mevalonic acid in the brains of rats on normal and protein deficient diets. The stereochemistry of tritium atoms at C-7 and C-15. | 1977 | J. Neurochem. | pmid:874493 |
Cornforth J | Symmetry of squalene epoxidation in vivo. | 1977 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:22855 |
Bhat CS and Ramasarma T | Rhythmic activity of utilization of mevalonate for biogenesis of cholesterol. | 1977 | Biochem. Biophys. Res. Commun. | pmid:836326 |
Burt VT et al. | The formation of menaquinone-4 (vitamin K) and its oxide in some marine invertebrates. | 1977 | Biochem. J. | pmid:849285 |
Ramsey RB and Fredericks M | Effect of hypocholesterolemic agents on central nervous system cholesterol biosynthesis. I. Zuclomiphene. | 1977 | Biochem. Pharmacol. | pmid:889582 |
Edwards PA et al. | Preferential uptake and utilization of mevalonolactone over mevalonate for sterol biosynthesis in isolated rat hepatocytes. | 1977 | Biochim. Biophys. Acta | pmid:901801 |
Edwards PA et al. | Control of 3-hydroxy-3-methylglutaryl coenzyme A reductase by endogenously synthesized sterols in vitro and in vivo. | 1977 | J. Biol. Chem. | pmid:14128 |
Stout RW | The effect of insulin and glucose on sterol synthesis in cultured rat arterial smooth muscle cells. | 1977 | Atherosclerosis | pmid:901624 |
Chang TY et al. | Isolation and partial characterization of a cholesterol-requiring mutant of Chinese hamster ovary cells. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:265577 |
McNamara DJ et al. | Measurement of daily cholesterol synthesis rates in man by assay of the fractional conversion of mevalonic acid to cholesterol. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:268653 |
Gibbons GF | Existence of metabolic reservoirs in the later stages of the cholesterol biosynthetic pathway. | 1977 | Biochem. Biophys. Res. Commun. | pmid:861038 |
Jakoi L and Quarfordt SH | Alterations of rat hepatic cholesterogenesis by heterologous lipoproteins. | 1977 | J. Biol. Chem. | pmid:197106 |
Balasubramaniam S et al. | Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16260 |
Wood SG and Gottlieb D | Evidence from mycelial studies for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. | 1978 | Biochem. J. | pmid:637849 |
Wood SG and Gottlieb D | Evidence from cell-free systems for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. | 1978 | Biochem. J. | pmid:637850 |
Takeuchi N et al. | Impairment of hepatic cholesterol synthesis from squalene and the function of hepatic sterol carrier protein system by ageing. | 1978 | Exp. Gerontol. | pmid:639893 |
Amdur BH et al. | Presence of squalene in gram-positive bacteria. | 1978 | J. Bacteriol. | pmid:670148 |
Parker TS et al. | Inhibition of liver prenyltransferase by alkyl phosphonates and phosphonophosphates. | 1978 | Biochim. Biophys. Acta | pmid:687653 |
Keyhani J and Keyhani E | Mevalonic acid as a precursor of the alkyl sidechain of heme a of cytochrome c oxidase in yeast Saccharomyces cerevisiae. | 1978 | FEBS Lett. | pmid:213310 |
Linder JR and Beitz DC | Sterol synthesis and CO2 production from mevalonate in calves. | 1978 | J. Lipid Res. | pmid:712243 |
Bhavnani BR and Woolever CA | Formation of steroids by the pregnant mare. VI. Metabolism of [14C]farnesyl pyrophosphate and [3H]dehydroepiandrosterone injected into the fetus. | 1978 | Endocrinology | pmid:155006 |
Nestel PJ et al. | The effect of dietary fat supplements on cholesterol metabolism in ruminants. | 1978 | J. Lipid Res. | pmid:712248 |
Allen KG and Klevay LM | Copper deficiency and cholesterol metabolism in the rat. | 1978 | Atherosclerosis | pmid:718736 |
Gustafsson J and Sjöstedt S | On the stereospecificity of microsomal "26"-hydroxylation in bile acid biosynthesis. | 1978 | J. Biol. Chem. | pmid:618857 |
Sable-Amplis R et al. | Abnormal liver cholesteryl ester storage in a strain of golden hamsters. Possible model for studies on cholesterol metabolism. | 1978 | Biochim. Biophys. Acta | pmid:718971 |
Bochenek W and Rodgers JB | Effects of saturated and unsaturated fats given with and without dietary cholesterol on hepatic cholesterol synthesis and hepatic lipid metabolism. | 1978 | Biochim. Biophys. Acta | pmid:620042 |
Mills JT and Adamany AM | Impairment of dolichyl saccharide synthesis and dolichol-mediated glycoprotein assembly in the aortic smooth muscle cell in culture by inhibitors of cholesterol biosynthesis. | 1978 | J. Biol. Chem. | pmid:670194 |
Mitropoulos KA et al. | On the mechanism for the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, of cholesterol 7alpha-hydroxylase and of acyl-coenzyme A:cholesterol acyltransferase by free cholesterol. | 1978 | Biochim. Biophys. Acta | pmid:687657 |
Betteridge DJ et al. | Compactin inhibits cholesterol synthesis in lymphocytes and intestinal mucosa from patients with familial hypercholesterolaemia. | 1978 Dec 23-30 | Lancet | pmid:82843 |
Marshall JD and Heiniger HJ | High affinity Concanavalin A binding to sterol-depleted L cells. | 1979 | J. Cell. Physiol. | pmid:489673 |
Löffler M and Schneider F | Unexpectedly low incorporation of isotopic acetate into lipids of Ehrlich ascites tumor cells cultured in lipid-poor medium. | 1979 | Oncology | pmid:37470 |
Cayen MN and Dvornik D | Effect of diosgenin on lipid metabolism in rats. | 1979 | J. Lipid Res. | pmid:438658 |
Faust JR et al. | Synthesis of ubiquinone and cholesterol in human fibroblasts: regulation of a branched pathway. | 1979 | Arch. Biochem. Biophys. | pmid:219777 |
Barter PJ and Lally JI | The metabolism of esterified cholesterol in rabbit plasma low density lipoproteins. | 1979 | Biochim. Biophys. Acta | pmid:219897 |
Rostas JA et al. | Selective labelling of two phases of axonal transport of cholesterol in the chick optic system. | 1979 | J. Neurochem. | pmid:86598 |
Calandra S et al. | Cholesterol synthesis in isolated rat hepatocytes. In vitro effect os sterols and bile acids. | 1979 | Exp. Mol. Pathol. | pmid:446695 |
Gonzalez R et al. | Two major regulatory steps in cholesterol synthesis by human renal cancer cells. | 1979 | Arch. Biochem. Biophys. | pmid:485166 |
Wiley MH et al. | Sex differences in the sterol and nonsterol metabolism of mevalonate. | 1979 | J. Biol. Chem. | pmid:762097 |
Quesney-Huneeus V et al. | Essential role for mevalonate synthesis in DNA replication. | 1979 | Proc. Natl. Acad. Sci. U.S.A. | pmid:291922 |
Ahmed AA et al. | Effect of milk constituents on hepatic cholesterol-genesis. | 1979 | Atherosclerosis | pmid:465119 |
Tabacik C et al. | Cholesterogenesis induction in human lymphocytes by sterols efflux or phytohemagglutinin stimulation : cellular division as the requirement for efficient cholesterol biosynthesis in lymphocytes. | 1979 | Biochem. Biophys. Res. Commun. | pmid:465064 |
Wiley MH et al. | Conversion of mevalonolactone to its open-chain salt by a serum enzyme. | 1979 | Biochem. Biophys. Res. Commun. | pmid:465057 |
Ortiz de Montellano PR et al. | Regulation of sterol biosynthesis and lysis of cultured hepatoma cells: inhibition of lanosterol demethylation by hydroxysterols. | 1979 | Biochem. Biophys. Res. Commun. | pmid:508352 |
Shama Bhat C and Ramasarma T | Inhibition of rat liver mevalonate pyrophosphate decarboxylase and mevalonate phosphate kinase by phenyl and phenolic compounds. | 1979 | Biochem. J. | pmid:226078 |
Popják G et al. | Determination of mevalonate in blood plasma in man and rat. Mevalonate "tolerance" tests in man. | 1979 | J. Lipid Res. | pmid:226640 |
Humphries GM and McConnell HM | Potent immunosuppression by oxidized cholesterol. | 1979 | J. Immunol. | pmid:368234 |
Barter PJ and Lally JI | In vitro exchanges of esterified cholesterol between serum lipoprotein fractions: studies of humans and rabbits. | 1979 | Metab. Clin. Exp. | pmid:216885 |
Subden RE and Renaud RL | Isolation of 4 alpha-methyl-5 alpha-ergosta-8,24(28)-dien-3 beta-ol from ester fractions of nutritionally deprived Neurospora crassa. | 1979 | Steroids | pmid:161433 |
Streuli RA et al. | Inhibition of human lymphocyte E-rosette formation by oxygenated sterols. | 1979 | J. Immunol. | pmid:501096 |
Ranganathan S et al. | The biosynthesis of ubiquinone in isolated rat heart cells. | 1979 | Arch. Biochem. Biophys. | pmid:518096 |
Frier BM and Saudek CD | Cholesterol metabolism in diabetes: the effect of insulin on the kinetics of plasma squalene. | 1979 | J. Clin. Endocrinol. Metab. | pmid:511973 |
Hughes PE and Tove SB | Synthesis of alpha-tocopherolquinone by the rat and its reduction by mitochondria. | 1980 | J. Biol. Chem. | pmid:7391070 |
Elliott JG and Lachance PA | Effects of vitamin A and ascorbic acid on in vitro cholesterol biosynthesis in the rat. | 1980 | J. Nutr. | pmid:7381607 |
Kita T et al. | Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. | 1980 | J. Clin. Invest. | pmid:6903572 |
Brown MS and Goldstein JL | Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. | 1980 | J. Lipid Res. | pmid:6995544 |
Lehoux JG and Preiss B | Regulation of hamster adrenal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. | 1980 | Endocrinology | pmid:6247136 |
Kritchevsky D et al. | Cholesterol synthesis in tissues of young and old Fisher 344 and Sprague-Dawley rats. | 1980 | Exp. Gerontol. | pmid:7428858 |
Yachnin S and Hsu R | Inhibition of human lymphocyte transformation by oxygenated sterol compounds. | 1980 | Cell. Immunol. | pmid:7363333 |
Chang TY and Limanek JS | Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells. | 1980 | J. Biol. Chem. | pmid:6105157 |
Curtiss LK and Edgington TS | Differences in the characteristics of inhibition of lymphocyte stimulation by 25-hydroxycholesterol and by the immunoregulatory serum lipoprotein LDL-In. | 1980 | J. Immunol. | pmid:7410845 |
George R and Goldfarb S | Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Morris hepatoma 7800 after intravenous injection of mevalonic acid. | 1980 | Cancer Res. | pmid:7438103 |
Kopito RR and Brunengraber H | (R)-mevalonate excretion in human and rat urines. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6255462 |
Turner JA and Prebble JN | Protection of cell viability and respiratory quinone levels by carotenoid in Micrococcus lysodeikticus (M. luteus). | 1980 | J. Gen. Microbiol. | pmid:7411117 |
Raulston DL et al. | Cycloheximide inhibits sterol biosynthesis in cell-free preparations of rat liver. | 1980 | J. Biol. Chem. | pmid:7372603 |
Menon AS et al. | Vanadate inhibits mevalonate synthesis and activates NADH oxidation in microsomes. | 1980 | FEBS Lett. | pmid:6900565 |
Swift IE and Milborrow BV | Retention of the 4-pro-R hydrogen atom of mevalonate at C-2,2' of bacterioruberin in Halobacterium halobium. | 1980 | Biochem. J. | pmid:7406867 |
Cuthbert JA and Lipsky PE | Sterol metabolism and lymphocyte function: inhibition of endogenous sterol biosynthesis does not prevent mitogen-induced human T lymphocyte activation. | 1980 | J. Immunol. | pmid:6965969 |
Feingold KR et al. | Sex difference in human mevalonate metabolism. | 1980 | J. Clin. Invest. | pmid:7400320 |
Sinensky M et al. | Somatic cell genetic analysis of regulation of expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6935672 |
Feingold KR et al. | Mevalonate metabolism in pregnant rats. | 1980 | Metab. Clin. Exp. | pmid:6774201 |
Duncan JL and Buckingham L | Resistance to streptolysin O in mammalian cells treated with oxygenated derivatives of cholesterol. Cholesterol content of resistant cells and recovery of streptolysin O sensitivity. | 1980 | Biochim. Biophys. Acta | pmid:7459354 |
Habenicht AJ et al. | Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor. | 1980 | J. Biol. Chem. | pmid:6768732 |
James MJ and Kandutsch AA | Elevated dolichol synthesis in mouse testes during spermatogenesis. | 1980 | J. Biol. Chem. | pmid:7350150 |
Hidaka K et al. | Growth of amphotericin B-resistant hamster cell line requires exogenous cholesterol. | 1980 | Exp. Cell Res. | pmid:7408982 |
Arebalo RE et al. | In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6256737 |
Hanson RF et al. | Stereochemistry of the side chain oxidation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol in man. | 1980 | J. Biol. Chem. | pmid:7354041 |
Erickson SK et al. | Studies on the mechanisms of the rapid modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in intact liver by mevalonolactone and 25-hydroxycholesterol. | 1980 | Biochim. Biophys. Acta | pmid:7417482 |
Drevon CA et al. | Regulation of cholesterol esterification and biosynthesis in monolayer cultures of normal adult rat hepatocytes. | 1980 | J. Biol. Chem. | pmid:7410416 |
Shao MJ and Lei KY | Conversion of [2-14C] mevalonate into cholesterol, lanosterol and squalene in copper-deficient rats. | 1980 | J. Nutr. | pmid:7373433 |
Nambudiri AM et al. | The role of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in the regulation of ubiquinone synthesis in human fibroblasts. | 1980 | J. Biol. Chem. | pmid:7380842 |
Shechter I et al. | A deficiency of mixed function oxidase activities in the cholesterol biosynthetic pathway of human granulocytes. | 1980 | J. Lipid Res. | pmid:7381322 |
Erickson SK et al. | Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro. | 1980 | J. Lipid Res. | pmid:7441061 |
Drevon CA et al. | Secretion of very low density lipoproteins enriched in cholesteryl esters by cultured rat hepatocytes during simulation of intracellular cholesterol esterification. | 1980 | J. Lipid Res. | pmid:7462802 |
Faust JR et al. | Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts. | 1980 | J. Biol. Chem. | pmid:7391033 |
Subbiah MT | Incorporation of 14C-mevalonate into biliary cholesterol and bile acids by perfused rat liver: effect of plasma and individual lipoproteins. | 1980 | Steroids | pmid:7444999 |