Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Thurnher M et al. | Novel aspects of mevalonate pathway inhibitors as antitumor agents. | 2012 | Clin. Cancer Res. | pmid:22529099 |
Hong SY et al. | Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. | 2012 | J. Appl. Microbiol. | pmid:22519412 |
Iwata A et al. | Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. | 2012 | Clin. Exp. Immunol. | pmid:22471285 |
Murphy LA et al. | Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22361350 |
Yasmin S et al. | Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22106303 |
Garcia-Ruiz C et al. | Statins and protein prenylation in cancer cell biology and therapy. | 2012 | Anticancer Agents Med Chem | pmid:22413970 |
Hu W et al. | Statins synergize dexamethasone-induced adipocyte fatty acid binding protein expression in macrophages. | 2012 | Atherosclerosis | pmid:22503826 |
Henriquez MA et al. | Effects of glucans and eicosapentaenoic acid on differential regulation of phenylpropanoid and mevalonic pathways during potato response to Phytophthora infestans. | 2012 | Plant Physiol. Biochem. | pmid:22922112 |
Khasnavis S and Pahan K | Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. | 2012 | J Neuroimmune Pharmacol | pmid:21701815 |
Drabkin HA and Gemmill RM | Cholesterol and the development of clear-cell renal carcinoma. | 2012 | Curr Opin Pharmacol | pmid:22939900 |
Conrado RJ et al. | DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. | 2012 | Nucleic Acids Res. | pmid:22021385 |
Yokota K et al. | Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. | 2011 Jan-Feb | Clin. Exp. Rheumatol. | pmid:21345291 |
Singh NK et al. | 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. | 2011 | Blood | pmid:21841162 |
Luo H et al. | Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. | 2011 | BMC Genomics | pmid:22369100 |
Youn YN et al. | Impact of High-Dose Statin Pretreatment in Patients with Stable Angina during Off-Pump Coronary Artery Bypass. | 2011 | Korean J Thorac Cardiovasc Surg | pmid:22263153 |
Odom AR | Five questions about non-mevalonate isoprenoid biosynthesis. | 2011 | PLoS Pathog. | pmid:22216001 |
Rauthan M and Pilon M | The mevalonate pathway in C. elegans. | 2011 | Lipids Health Dis | pmid:22204706 |
Emma F et al. | Renal mitochondrial cytopathies. | 2011 | Int J Nephrol | pmid:21811680 |
Ageenko NV et al. | Expression of Pigment Cell-Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius. | 2011 | Evid Based Complement Alternat Med | pmid:21804858 |
Cheng G et al. | Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. | 2011 | Cancer Biol. Ther. | pmid:21799303 |
Katuru R et al. | Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21540247 |
Peng LF et al. | Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. | 2011 | J. Infect. Dis. | pmid:21791663 |
Bajgain P et al. | Transcriptome characterization and polymorphism detection between subspecies of big sagebrush (Artemisia tridentata). | 2011 | BMC Genomics | pmid:21767398 |
Scheller EL et al. | Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. | 2011 | J. Cell. Biochem. | pmid:21751240 |
Waldron J and Webster C | Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. | 2011 | Ann. Clin. Biochem. | pmid:21355014 |
Soliman SS et al. | Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways. | 2011 | J. Nat. Prod. | pmid:22103292 |
Zhang B et al. | A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. | 2011 | Biochemistry | pmid:21438569 |
Henneman L et al. | Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS. | 2011 | Biochim. Biophys. Acta | pmid:21237288 |
Kim RH et al. | Bisphosphonates induce senescence in normal human oral keratinocytes. | 2011 | J. Dent. Res. | pmid:21427353 |
Kyathanahalli CN and Kowluru A | A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGEâ‚‚. | 2011 | Biochem. Pharmacol. | pmid:21406184 |
Zhao Y et al. | Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. | 2011 | J. Invest. Dermatol. | pmid:21390048 |
Blankier S et al. | The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease. | 2011 | Clin. Exp. Immunol. | pmid:21361911 |
Ghavami S et al. | Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. | 2011 | PLoS ONE | pmid:21304979 |
Ignea C et al. | Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. | 2011 | Microb. Cell Fact. | pmid:21276210 |
Tuckow AP et al. | Simvastatin represses protein synthesis in the muscle-derived Câ‚‚Câ‚â‚‚ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:21224482 |
Tsubaki M et al. | Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma. | 2011 | Cytokine | pmid:21292498 |
Sawai S and Saito K | Triterpenoid biosynthesis and engineering in plants. | 2011 | Front Plant Sci | pmid:22639586 |
Nishikawa Y et al. | Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages. | 2011 | J. Vet. Med. Sci. | pmid:21187676 |
Tsuyuki R et al. | Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride. | 2011 | J. Agric. Food Chem. | pmid:21299216 |
Nilsson S et al. | Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells. | 2011 | Cancer Lett. | pmid:21356574 |
Liu Q et al. | Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. | 2011 | PLoS ONE | pmid:21858047 |
Epplen R et al. | Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. | 2011 | Acta Oncol | pmid:20429730 |
Jouneau S et al. | Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. | 2011 | PLoS ONE | pmid:21826199 |
Murtola TJ et al. | Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL. | 2011 | Eur. J. Pharmacol. | pmid:22040920 |
Issat T et al. | Antitumor effects of the combination of cholesterol reducing drugs. | 2011 | Oncol. Rep. | pmid:21491092 |
Castella B et al. | Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. | 2011 | J. Immunol. | pmid:21753152 |
Kim YS et al. | Increase of lycopene production by supplementing auxiliary carbon sources in metabolically engineered Escherichia coli. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21246354 |
Jang HJ et al. | Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. | 2011 | Microb. Cell Fact. | pmid:21801353 |
Leichner GS et al. | Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. | 2011 | J. Biol. Chem. | pmid:21778231 |
Yanae M et al. | Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. | 2011 | J. Exp. Clin. Cancer Res. | pmid:21831290 |