Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
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Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
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Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ramachandran CK and Shah SN | Decarboxylation of mevalonate pyrophosphate is one rate-limiting step in hepatic cholesterol synthesis in suckling and weaned rats. | 1976 | Biochem. Biophys. Res. Commun. | pmid:177019 |
| Nes WD et al. | Metabolism of mevalonic acid to long chain fatty alcohols in an insect. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181890 |
| Rao GS and Ramasarma T | ATP in the regulation of cholesterol biosynthesis- a supra-energetic role. | 1972 | Biochem. Biophys. Res. Commun. | pmid:5077855 |
| Wang Y et al. | 24S,25-Epoxycholesterol in mouse and rat brain. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24832732 |
| Heintz R et al. | Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4344813 |
| Chan PC et al. | Lovastatin increases surface low density lipoprotein receptor expression by retarding the receptor internalization rate in proliferating lymphocytes. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9196047 |
| Szkopińska A et al. | The regulation of activity of main mevalonic acid pathway enzymes: farnesyl diphosphate synthase, 3-hydroxy-3-methylglutaryl-CoA reductase, and squalene synthase in yeast Saccharomyces cerevisiae. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623644 |
| Sagami H et al. | Novel isoprenoid modified proteins in Halobacteria. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8093082 |
| Hu ZY et al. | Neurosteroids: steroidogenesis in primary cultures of rat glial cells after release of aminoglutethimide blockade. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2735928 |
| Sablé-Amplis R and Sicart R | Evidence for negative feedback control of cholesterogenesis from mevalonate in liver: absence in the intestine of guinea pigs fed a 0.5% cholesterol diet. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181883 |
| Cenedella RJ et al. | Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1510688 |
| Keller RK and Fliesler SJ | Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10600541 |
| Fuhrman B et al. | Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9168909 |
| Polo MP and de Bravo MG | Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2. | 2006 | Biochem. Cell Biol. | pmid:16462894 |
| Polo MP et al. | Effect of ethanol on cell growth and cholesterol metabolism in cultured Hep G2 cells. | 2003 | Biochem. Cell Biol. | pmid:14663504 |
| Silber JR et al. | The effect of mevalonic acid deprivation on enzymes of DNA replication in cells emerging from quiescence. | 1992 | Biochem. J. | pmid:1281982 |
| Malathi P and Ganguly J | Studies on metabolism of vitamin A. 8. Effect of ascorbate on isoprenoid metabolism in vitamin A-deficient rats. | 1964 | Biochem. J. | pmid:5837438 |
| Ellsworth JL et al. | Evidence for sterol-independent regulation of low-density lipoprotein receptor activity in Hep-G2 cells. | 1991 | Biochem. J. | pmid:1930137 |
| Konrad Z and Eichler J | Lipid modification of proteins in Archaea: attachment of a mevalonic acid-based lipid moiety to the surface-layer glycoprotein of Haloferax volcanii follows protein translocation. | 2002 | Biochem. J. | pmid:12069685 |
| Henry A et al. | Dolichol biosynthesis in human malignant cells. | 1991 | Biochem. J. | pmid:1654890 |
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| Iglesias J and Gibbons GF | Regulation of hepatic cholesterol biosynthesis. Effects of a cytochrome P-450 inhibitor on the formation and metabolism of oxygenated sterol products of lanosterol. | 1989 | Biochem. J. | pmid:2604729 |
| Richards JB and Hemming FW | Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. | 1972 | Biochem. J. | pmid:4643705 |
| Smith AG and Goad LJ | Sterol biosynthesis in the echinoderm Asterias rubens. | 1975 | Biochem. J. | pmid:1147897 |
| Wellburn AR and Hampp R | Uptake of mevalonate and acetate during plastid development. | 1976 | Biochem. J. | pmid:985424 |
| Konrad M and Merz WE | Long-term effect of cyclic AMP on N-glycosylation is caused by an increase in the activity of the cis-prenyltransferase. | 1996 | Biochem. J. | pmid:8687403 |
| Flint AP | The activity and kinetic properties of mevalonate kinase in superovulated rat ovary. | 1970 | Biochem. J. | pmid:4321929 |
| Green TR and Baisted DJ | Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination. | 1972 | Biochem. J. | pmid:4348263 |
| Azrolan NI and Coleman PS | A discoordinate increase in the cellular amount of 3-hydroxy-3-methylglutaryl-CoA reductase results in the loss of rate-limiting control over cholesterogenesis in a tumour cell-free system. | 1989 | Biochem. J. | pmid:2705993 |
| Wilton DC | The effect of excess mevalonic acid on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. | 1985 | Biochem. J. | pmid:3929773 |
| Wilton DC | The effect of cholesterol on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. | 1983 | Biochem. J. | pmid:6418144 |
| Disch A et al. | Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. | 1998 | Biochem. J. | pmid:9657979 |
| Swift IE and Milborrow BV | Retention of the 4-pro-R hydrogen atom of mevalonate at C-2,2' of bacterioruberin in Halobacterium halobium. | 1980 | Biochem. J. | pmid:7406867 |
| Burt VT et al. | The formation of menaquinone-4 (vitamin K) and its oxide in some marine invertebrates. | 1977 | Biochem. J. | pmid:849285 |
| Gibbons GF and Mitropoulos KA | The effect of carbon monoxide on the nature of the accumulated 4,4-dimethyl sterol precursors of cholesterol during its biosynthesis from (2-14C)mevalonic acid in vitro. | 1973 | Biochem. J. | pmid:4724584 |
| Swift IE and Milborrow BV | Stereochemistry of allene biosynthesis and the formation of the acetylenic carotenoid diadinoxanthin and peridinin (C37) from neoxanthin. | 1981 | Biochem. J. | pmid:7337715 |
| Jayaram M and Raman TS | Metabolism of ergosterol in the larva of the rice moth (Corcyra cephalonica St.). | 1972 | Biochem. J. | pmid:5085614 |
| Nave JF et al. | Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. | 1985 | Biochem. J. | pmid:2986604 |
| Martin HG and Thorne KJ | Synthesis of radioactive dolichol from (4S-3H)mevalonate in the regenerating rat liver. | 1974 | Biochem. J. | pmid:4822733 |
| Moshier SE and Chapman DJ | Biosynthetic studies on aromatic carotenoids. Biosynthesis of chlorobactene. | 1973 | Biochem. J. | pmid:4774401 |
| Gregory KW et al. | Diurnal variations in rat liver 3-hydroxy-3-methylglutaryl-Coenzyme A reductase activity in relation to feeding. | 1972 | Biochem. J. | pmid:4656802 |
| Kam NT et al. | Effect of lovastatin on acyl-CoA: cholesterol O-acyltransferase (ACAT) activity and the basolateral-membrane secretion of newly synthesized lipids by CaCo-2 cells. | 1990 | Biochem. J. | pmid:2268271 |
| Hornby GM and Boyd GS | The origin of lanosta-7,24-dienol in rat skin. | 1971 | Biochem. J. | pmid:5131739 |
| Richards JB et al. | Dolichol phosphates as acceptors of mannose from guanosine diphosphate mannose in liver systems. | 1971 | Biochem. J. | pmid:5131017 |
| Thorne KJ and Barker DC | The bactoprenol content of plasma and mesosome membranes from Lactobacillus casei. | 1971 | Biochem. J. | pmid:5001951 |
| Milborrow BV and Noddle RC | Conversion of 5-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-methylpenta-cis-2-trans-4-dienoic acid into abscisic acid in plants. | 1970 | Biochem. J. | pmid:5493506 |
| Green TR and Baisted DJ | Development of the squalene-synthesizing system during early stages of pea seed germination. | 1971 | Biochem. J. | pmid:4335540 |
| Bolger LM et al. | Biosynthesis of 24-ethylcholesta-5,22,25-trien-3-beta-ol, a new sterol from Clerodendrum campbellii. | 1970 | Biochem. J. | pmid:5472151 |
| Ginger ML et al. | Elucidation of carbon sources used for the biosynthesis of fatty acids and sterols in the trypanosomatid Leishmania mexicana. | 1999 | Biochem. J. | pmid:10455027 |
| Gough DP et al. | The characterization of undecaprenol of Lactobacillus plantarum. | 1970 | Biochem. J. | pmid:5472148 |
| Atkin SD et al. | The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. | 1972 | Biochem. J. | pmid:4655417 |
| De Souza NJ et al. | Studies on insect moulting hormones: biosynthesis of ponasterone A and ecdysterone from [2-14C] mevalonate in Taxus baccata. | 1969 | Biochem. J. | pmid:5343810 |
| Bolger LM et al. | Incorporation of [2-14C] mevalonic acid into 28-isofucosterol by leaves of Pisum sativum. | 1969 | Biochem. J. | pmid:5343809 |
| Hepper CM and Audley BG | Th biosynthesis of rubber from beta-hydroxy-beta-methylgluarylcoenzyme A in Hevea brasiliensis latex. | 1969 | Biochem. J. | pmid:4390212 |
| Buggy MJ et al. | Stereochemistry of phytoene biosynthesis by isolated chloroplasts. | 1969 | Biochem. J. | pmid:4309532 |
| Robinson DR and Ryback G | Incorporation of tritium from [(4R)-4-3H]mevalonate into abscisic acid. | 1969 | Biochem. J. | pmid:5821014 |
| Rees HH et al. | Studies in phytosterol biosynthesis. Mechanism of biosynthesis of cycloartenol. | 1968 | Biochem. J. | pmid:4297048 |
| West CA | Gibberellins and their biosynthesis. | 1969 | Biochem. J. | pmid:5810062 |
| Francis MJ and Allcock C | Monoterpene beta-D-glucosides in roses: isolation and formation from DL-2-14C mevalonate. | 1969 | Biochem. J. | pmid:5807204 |
| Reid WW | Effect of SKF7997 and SKF525 on diterpene and sterol biosynthesis in Gibberella fujikori from [2-14C] mevalonate. | 1969 | Biochem. J. | pmid:5807203 |
| Gray JC and Kekwick RG | Mevalonate kinase from etiolated cotyledons of French beans. | 1969 | Biochem. J. | pmid:5807202 |
| Austin DG et al. | Trisporic acid biosynthesis and carotenogenesis in Blakesleea trispora. | 1969 | Biochem. J. | pmid:5807198 |
| Hill HM and Rogers LJ | Conversion of lycopene into beta-carotene by chloroplasts of higher plants. | 1969 | Biochem. J. | pmid:5807194 |
| Barr RM and Hemming FW | Polyprenol phosphate as an acceptor of mannose from guanosine diphosphate mannose in Aspergillus niger. | 1972 | Biochem. J. | pmid:5073732 |
| Liuzzi A and Foppen FH | Sterol-like compound from sensory ganglia. Effect of a nerve growth factor and insulin on its biosynthesis. | 1968 | Biochem. J. | pmid:5641875 |
| Parsons RB et al. | Statins inhibit the dimerization of beta-secretase via both isoprenoid- and cholesterol-mediated mechanisms. | 2006 | Biochem. J. | pmid:16803455 |
| Williams RJ et al. | The biosynthesis of cyclic carotenes. | 1967 | Biochem. J. | pmid:6060456 |
| Wieckowski S and Goodwin TW | Incorporation of DL-[2-14C]mevalonic acid lactone into beta-carotene and the phytol side chain of chlorophyll in cotyledons of four species of pine seedlings. | 1967 | Biochem. J. | pmid:6060454 |
| Gough DP and Hemming FW | The stereochemistry of betulaprenol biosynthesis. | 1967 | Biochem. J. | pmid:6056617 |
| Rodwell VW | Cholesterol regulation of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1972 | Biochem. J. | pmid:5085556 |
| Rees HH et al. | The biosynthesis of beta-amyrin. Mechanism of squalene cyclization. | 1968 | Biochem. J. | pmid:5639923 |
| Rogers LJ et al. | Mevalonate-kinase isoenzymes in plant cells. | 1966 | Biochem. J. | pmid:5968528 |
| Goad LJ and Goodwin TW | The biosynthesis of sterols in higher plants. | 1966 | Biochem. J. | pmid:5964970 |
| Rees HH et al. | The stereospecific biosynthesis of plant sterols and alpha- and beta-amyrin. | 1966 | Biochem. J. | pmid:5964969 |
| Rogers LJ et al. | Intracellular localization of mevalonate-activating enzymes in plant cells. | 1966 | Biochem. J. | pmid:5947149 |
| Treharne KJ et al. | Incorporation of [14C] carbon dioxide and [2-14C] mevalonic acid into terpenoids of higher plants during chloroplast development. | 1966 | Biochem. J. | pmid:5965341 |
| Fears R | The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function. | 1981 | Biochem. J. | pmid:7039614 |
| Thorne KJ and Kodicek E | The structure of bactoprenol, a lipid formed by lactobacilli from mevalonic acid. | 1966 | Biochem. J. | pmid:5965329 |
| Overton KH and Roberts FM | Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. | 1974 | Biochem. J. | pmid:4468823 |
| Molowa DT and Cimis GM | Co-ordinate regulation of low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase and synthase gene expression in HepG2 cells. | 1989 | Biochem. J. | pmid:2569863 |
| Joshi VC et al. | Biosynthetic relationship between ubichromenol and ubiquinone. | 1964 | Biochem. J. | pmid:5838088 |
| Gavigan SJ and Knight BL | The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. | 1983 | Biochem. J. | pmid:6651782 |
| Campos N et al. | Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. | 2001 | Biochem. J. | pmid:11115399 |
| Milborrow BV | Stereochemical aspects of the formation of double bonds in abscisic acid. | 1972 | Biochem. J. | pmid:4643698 |
| RAMASARMA T and RAMAKRISHNAN T | Incorporation of [2-14C]mevalonic acid and [2-14C]acetic acid into lipids of mycobacteria. | 1961 | Biochem. J. | pmid:14038591 |
| Banthorpe DV et al. | Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium graveolens and Rosa dilecta. | 1972 | Biochem. J. | pmid:4348258 |
| Campia I et al. | Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes. | 2012 | Biochem. J. | pmid:22845468 |
| Knöss W et al. | Biosynthesis of the labdane diterpene marrubiin in Marrubium vulgare via a non-mevalonate pathway. | 1997 | Biochem. J. | pmid:9291117 |
| Disch A et al. | Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. | 1998 | Biochem. J. | pmid:9531505 |
| Farrell FX et al. | Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated. | 1993 | Biochem. J. | pmid:8424780 |
| Percy-Robb IW and Boyd GS | The synthesis of bile acids in perfused rat liver subjected to chronic biliary drainage. | 1970 | Biochem. J. | pmid:5472179 |
| Goad LJ et al. | Incorporation of (2-14C, (5r)-5-3H1) mevalonic acid into cholesterol by a rat liver homogenate and into beta-sitosterol and 28-isofucosterol by larix decidua leaves. | 1969 | Biochem. J. | pmid:5348842 |
| Barr RM and Hemming FW | Polyprenols of Aspergillus niger. Their characterization, biosynthesis and subcellular distribution. | 1972 | Biochem. J. | pmid:5073731 |
| Wade DP et al. | Independent regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and chylomicron remnant receptor activities in rat liver. | 1984 | Biochem. J. | pmid:6324750 |
| Thorne KJ | Incorporation of radioactive mevalonate into C50 and C55 phenols by Streptococcus mutans. | 1973 | Biochem. J. | pmid:4772282 |
| Derksen A et al. | Non-human primate platelets and arterial tissue cannot convert preformed [14C]lanosterol into[14C]cholesterol in vivo. | 1976 | Biochem. J. | pmid:822845 |
| Grönroos E et al. | Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. | 1996 | Biochem. J. | pmid:8645211 |
| Scharf SS and Simpson KL | Attempts to detect lycopersene formation in yeast. | 1968 | Biochem. J. | pmid:5753091 |
| Booth R et al. | The effect of dietary cholesterol on cholesterol biosynthesis and other processes in mammalian liver. | 1971 | Biochem. J. | pmid:5124798 |
| Li G et al. | Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins. | 1993 | Biochem. J. | pmid:8424783 |