Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Jauhiainen M et al. | Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19665949 |
Anthony JR et al. | Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene. | 2009 | Metab. Eng. | pmid:18775787 |
Lorenzen W et al. | Isoprenoids are essential for fruiting body formation in Myxococcus xanthus. | 2009 | J. Bacteriol. | pmid:19617362 |
Zhao S et al. | Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones. | 2009 | Bioorg. Med. Chem. | pmid:19879766 |
Xu Q et al. | Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. | 2009 | BMC Genomics | pmid:19922663 |
Rothwell C et al. | Cholesterol biosynthesis modulation regulates dengue viral replication. | 2009 | Virology | pmid:19419745 |
Dje N'Guessan P et al. | Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19122173 |
Iriti M and Faoro F | Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. | 2009 | Int J Mol Sci | pmid:20111684 |
Jawaid S et al. | Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). | 2009 | PLoS ONE | pmid:20011597 |
Raemer PC et al. | Statins inhibit NK-cell cytotoxicity by interfering with LFA-1-mediated conjugate formation. | 2009 | Eur. J. Immunol. | pmid:19424968 |
Chang PK et al. | Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. | 2009 | Toxins (Basel) | pmid:22069533 |
Kirmizis D and Chatzidimitriou D | Pleiotropic vasoprotective effects of statins: the chicken or the egg? | 2009 | Drug Des Devel Ther | pmid:19920934 |
Eldor R and Raz I | American Diabetes Association indications for statins in diabetes: is there evidence? | 2009 | Diabetes Care | pmid:19875586 |
Massonnet B et al. | Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes. | 2009 | Eur. Cytokine Netw. | pmid:19825520 |
Wang W et al. | Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing. | 2009 | BMC Genomics | pmid:19818120 |
Brahmachari S et al. | Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. | 2009 | J. Immunol. | pmid:19812204 |
Montoya CJ et al. | Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trial. | 2009 | Trials | pmid:19538732 |
Li J et al. | Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells. | 2009 | J. Immunol. | pmid:19494338 |
Suzuki M et al. | Complete blockage of the mevalonate pathway results in male gametophyte lethality. | 2009 | J. Exp. Bot. | pmid:19363204 |
Balibar CJ et al. | The mevalonate pathway of Staphylococcus aureus. | 2009 | J. Bacteriol. | pmid:19028897 |
Khan MA et al. | Statins impair CD1d-mediated antigen presentation through the inhibition of prenylation. | 2009 | J. Immunol. | pmid:19342651 |
Alvarez Y et al. | Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19318593 |
Niessen J et al. | Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin. | 2009 | Drug Metab. Dispos. | pmid:19237515 |
Lachmann HJ and Hawkins PN | Developments in the scientific and clinical understanding of autoinflammatory disorders. | 2009 | Arthritis Res. Ther. | pmid:19232070 |
Kim WY et al. | Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation. | 2009 | J. Neurochem. | pmid:19209406 |
Zeiser R et al. | Regulation of different inflammatory diseases by impacting the mevalonate pathway. | 2009 | Immunology | pmid:19191903 |
Yeger-Lotem E et al. | Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity. | 2009 | Nat. Genet. | pmid:19234470 |
Knight LA et al. | Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay. | 2009 | BMC Cancer | pmid:19175937 |
Deshpande G et al. | Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration. | 2009 | PLoS Genet. | pmid:19132091 |
Mansouri H et al. | Effects of gibberellic acid on primary terpenoids and delta-tetrahydrocannabinol in Cannabis sativa at flowering stage. | 2009 | J Integr Plant Biol | pmid:19522814 |
Olson AL et al. | Substrate induced structural and dynamics changes in human phosphomevalonate kinase and implications for mechanism. | 2009 | Proteins | pmid:18798562 |
Sillero MA et al. | Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. | 2009 | Biochem. Pharmacol. | pmid:19414000 |
Dueber JE et al. | Synthetic protein scaffolds provide modular control over metabolic flux. | 2009 | Nat. Biotechnol. | pmid:19648908 |
Leszczynska A et al. | Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. | 2009 | PLoS ONE | pmid:20041128 |
Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |
Fujimoto M et al. | Fluvastatin inhibits mast cell degranulation without changing the cytoplasmic Ca2+ level. | 2009 | Eur. J. Pharmacol. | pmid:19059394 |
Sun X et al. | Identified biosynthetic pathway of aspergiolide A and a novel strategy to increase its production in a marine-derived fungus Aspergillus glaucus by feeding of biosynthetic precursors and inhibitors simultaneously. | 2009 | Bioresour. Technol. | pmid:19386490 |
Sidorkiewicz M et al. | Mevalonate pathway modulation is associated with hepatitis C virus RNA presence in peripheral blood mononuclear cells. | 2009 | Virus Res. | pmid:19540284 |
Bełtowski J et al. | Adverse effects of statins - mechanisms and consequences. | 2009 | Curr Drug Saf | pmid:19534648 |
GarcÃa I et al. | QSAR and complex network study of the chiral HMGR inhibitor structural diversity. | 2009 | Bioorg. Med. Chem. | pmid:19026553 |
Ohyama K et al. | Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19139393 |
Kroll J et al. | Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology. | 2009 | Metab. Eng. | pmid:19558962 |
Wali VB et al. | Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment. | 2009 | Lipids | pmid:19777282 |
Rekittke I et al. | Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. | 2008 | J. Am. Chem. Soc. | pmid:19035630 |
Kervizic G and Corcos L | Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. | 2008 | BMC Syst Biol | pmid:19025648 |
Glynn SA et al. | The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. | 2008 | BMC Cancer | pmid:18199328 |
Galichet A et al. | Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. | 2008 | Plant Physiol. | pmid:18184738 |
Martin-Ventura JL et al. | LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin. | 2008 | Atherosclerosis | pmid:18378243 |
Tarhzaoui K et al. | Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetes. | 2008 | Diabetes Res. Clin. Pract. | pmid:18406000 |
de Ruyck J and Wouters J | Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. | 2008 | Curr. Protein Pept. Sci. | pmid:18393884 |