Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
DiNicolantonio JJ | CoQ10 and L-carnitine for statin myalgia? | 2012 | Expert Rev Cardiovasc Ther | pmid:23190071 |
Aliferis KA and Jabaji S | FT-ICR/MS and GC-EI/MS metabolomics networking unravels global potato sprout's responses to Rhizoctonia solani infection. | 2012 | PLoS ONE | pmid:22880040 |
Zaidi N et al. | ATP-citrate lyase: a key player in cancer metabolism. | 2012 | Cancer Res. | pmid:22787121 |
Matsuoka T et al. | An ultrasensitive enzymatic method for measuring mevalonic acid in serum. | 2012 | J. Lipid Res. | pmid:22715156 |
Van Laar TA et al. | Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi. | 2012 | PLoS ONE | pmid:22675445 |
Ginestier C et al. | Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target. | 2012 | Stem Cells | pmid:22605458 |
Liu D et al. | The genome of Ganoderma lucidum provides insights into triterpenes biosynthesis and wood degradation [corrected]. | 2012 | PLoS ONE | pmid:22567134 |
Yang J et al. | Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. | 2012 | PLoS ONE | pmid:22558074 |
Thurnher M et al. | Novel aspects of mevalonate pathway inhibitors as antitumor agents. | 2012 | Clin. Cancer Res. | pmid:22529099 |
Hong SY et al. | Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. | 2012 | J. Appl. Microbiol. | pmid:22519412 |
Iwata A et al. | Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. | 2012 | Clin. Exp. Immunol. | pmid:22471285 |
Luvai A et al. | Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. | 2012 | Clin Med Insights Cardiol | pmid:22442638 |
Lachenmeier DW et al. | NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements. | 2012 | Chin Med | pmid:22439629 |
Mosqueda J et al. | Current advances in detection and treatment of babesiosis. | 2012 | Curr. Med. Chem. | pmid:22360483 |
Hyldgaard M et al. | Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. | 2012 | Front Microbiol | pmid:22291693 |
Ma Y et al. | Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. | 2012 | J. Exp. Bot. | pmid:22291132 |
Keizer HG | The "Mevalonate hypothesis": a cholesterol-independent alternative for the etiology of atherosclerosis. | 2012 | Lipids Health Dis | pmid:23122424 |
Yano K | Lipid metabolic pathways as lung cancer therapeutic targets: a computational study. | 2012 | Int. J. Mol. Med. | pmid:22211244 |
Shimane M et al. | Mevalonate-dependent enzymatic synthesis of amorphadiene driven by an ATP-regeneration system using polyphosphate kinase. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22878192 |
Mans RA et al. | Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. | 2012 | Neuroscience | pmid:22192838 |
Fu X et al. | Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. | 2012 | J. Exp. Bot. | pmid:21994170 |
Murphy LA et al. | Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22361350 |
Zhou K et al. | Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production. | 2012 | PLoS ONE | pmid:23133596 |
Fuhrmeister J et al. | Prooxidative toxicity and selenoprotein suppression by cerivastatin in muscle cells. | 2012 | Toxicol. Lett. | pmid:23092657 |
Yasmin S et al. | Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22106303 |
Scalcinati G et al. | Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae. | 2012 | Microb. Cell Fact. | pmid:22938570 |
Li X et al. | Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains. | 2012 | Genet. Sel. Evol. | pmid:22682430 |
Panicker SP et al. | Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia. | 2012 | PLoS ONE | pmid:22685570 |
Guo H et al. | Rosuvastatin may modulate insulin signaling and inhibit atherogenesis beyond its plasma cholesterol-lowering effect in insulin-resistant mice. | 2012 | Cardiovasc Drugs Ther | pmid:22918601 |
Trapani L et al. | 3-hydroxy 3-methylglutaryl coenzyme A reductase inhibition impairs muscle regeneration. | 2012 | J. Cell. Biochem. | pmid:22274883 |
Nürenberg G and Volmer DA | The analytical determination of isoprenoid intermediates from the mevalonate pathway. | 2012 | Anal Bioanal Chem | pmid:21789486 |
Garcia-Ruiz C et al. | Statins and protein prenylation in cancer cell biology and therapy. | 2012 | Anticancer Agents Med Chem | pmid:22413970 |
Wu S et al. | Engineering triterpene metabolism in tobacco. | 2012 | Planta | pmid:22729821 |
Hu W et al. | Statins synergize dexamethasone-induced adipocyte fatty acid binding protein expression in macrophages. | 2012 | Atherosclerosis | pmid:22503826 |
Henriquez MA et al. | Effects of glucans and eicosapentaenoic acid on differential regulation of phenylpropanoid and mevalonic pathways during potato response to Phytophthora infestans. | 2012 | Plant Physiol. Biochem. | pmid:22922112 |
Song AA et al. | Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production. | 2012 | PLoS ONE | pmid:23300671 |
Partow S et al. | Reconstruction and evaluation of the synthetic bacterial MEP pathway in Saccharomyces cerevisiae. | 2012 | PLoS ONE | pmid:23285068 |
Yang D et al. | Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. | 2012 | PLoS ONE | pmid:23209548 |
Hussain MS et al. | Current approaches toward production of secondary plant metabolites. | 2012 | J Pharm Bioallied Sci | pmid:22368394 |
Iguchi K | [Effect of bisphosphonates on anticancer activity in prostate cancer cells]. | 2012 | Yakugaku Zasshi | pmid:23023419 |
Haines BE et al. | Molecular modeling of the reaction pathway and hydride transfer reactions of HMG-CoA reductase. | 2012 | Biochemistry | pmid:22971202 |
Coscia M et al. | Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells. | 2012 | Blood | pmid:22932792 |
Malenda A et al. | Statins impair glucose uptake in tumor cells. | 2012 | Neoplasia | pmid:22577346 |
Garjani A et al. | Ambivalent effects of atorvastatin on angiogenesis, epidermal cell proliferation and tumorgenesis in animal models. | 2012 | Iran. Biomed. J. | pmid:22801278 |
Ginestier C et al. | p53 and cancer stem cells: the mevalonate connexion. | 2012 | Cell Cycle | pmid:22751434 |
Roy A et al. | Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. | 2012 | PLoS ONE | pmid:22723850 |
Ghavami S et al. | Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. | 2012 | Cell Death Dis | pmid:22717585 |
Reiniers MJ et al. | 2',7'-Dichlorofluorescein is not a probe for the detection of reactive oxygen and nitrogen species. | 2012 | J. Hepatol. | pmid:22127279 |
Khasnavis S and Pahan K | Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. | 2012 | J Neuroimmune Pharmacol | pmid:21701815 |
Plée-Gautier E et al. | Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism. | 2012 | Biochem. Pharmacol. | pmid:22634049 |
Paintlia AS et al. | Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis. | 2012 | Am. J. Pathol. | pmid:22796435 |
Drabkin HA and Gemmill RM | Cholesterol and the development of clear-cell renal carcinoma. | 2012 | Curr Opin Pharmacol | pmid:22939900 |
Rad SA et al. | Type 2 IDI performs better than type 1 for improving lycopene production in metabolically engineered E. coli strains. | 2012 | World J. Microbiol. Biotechnol. | pmid:22806807 |
Campia I et al. | Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes. | 2012 | Biochem. J. | pmid:22845468 |
Fatima T et al. | Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. | 2012 | PLoS ONE | pmid:22558083 |
Zhang B et al. | Interference in mevalonate pathway ameliorates homocysteine-induced endothelium-dysfunction. | 2012 | Eur. J. Pharmacol. | pmid:22796672 |
Conrado RJ et al. | DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. | 2012 | Nucleic Acids Res. | pmid:22021385 |
Roullet JB et al. | No evidence for mevalonate shunting in moderately affected children with Smith-Lemli-Opitz syndrome. | 2012 | J. Inherit. Metab. Dis. | pmid:22391996 |
Barta ML et al. | Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. | 2012 | Biochemistry | pmid:22734632 |
Jiang Q et al. | Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide. | 2012 | Int. J. Cancer | pmid:21400505 |
Li J et al. | Atorvastatin inhibits myocardin expression in vascular smooth muscle cells. | 2012 | Hypertension | pmid:22615115 |
Yokota K et al. | Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. | 2011 Jan-Feb | Clin. Exp. Rheumatol. | pmid:21345291 |
Li Z et al. | Effect of temperature on postillumination isoprene emission in oak and poplar. | 2011 | Plant Physiol. | pmid:21177471 |
Yu F et al. | Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. | 2011 | Cell. Mol. Life Sci. | pmid:20730551 |
Youn YN et al. | Impact of High-Dose Statin Pretreatment in Patients with Stable Angina during Off-Pump Coronary Artery Bypass. | 2011 | Korean J Thorac Cardiovasc Surg | pmid:22263153 |
Odom AR | Five questions about non-mevalonate isoprenoid biosynthesis. | 2011 | PLoS Pathog. | pmid:22216001 |
Rauthan M and Pilon M | The mevalonate pathway in C. elegans. | 2011 | Lipids Health Dis | pmid:22204706 |
Barrero RA et al. | De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes. | 2011 | BMC Genomics | pmid:22151917 |
Leszczynska A et al. | Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study. | 2011 | Acta Biochim. Pol. | pmid:22132374 |
Ramgolam VS and Markovic-Plese S | Regulation of suppressors of cytokine signaling as a therapeutic approach in autoimmune diseases, with an emphasis on multiple sclerosis. | 2011 | J Signal Transduct | pmid:22132325 |
Cho SH et al. | Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller. | 2011 | Nutr Res Pract | pmid:22125678 |
Tijerino A et al. | Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. | 2011 | Toxins (Basel) | pmid:22069764 |
Katuru R et al. | Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21540247 |
Peng LF et al. | Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. | 2011 | J. Infect. Dis. | pmid:21791663 |
Bajgain P et al. | Transcriptome characterization and polymorphism detection between subspecies of big sagebrush (Artemisia tridentata). | 2011 | BMC Genomics | pmid:21767398 |
Scheller EL et al. | Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. | 2011 | J. Cell. Biochem. | pmid:21751240 |
Sun S and McKenna CE | Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010). | 2011 | Expert Opin Ther Pat | pmid:21702715 |
Rizzo WB | The role of fatty aldehyde dehydrogenase in epidermal structure and function. | 2011 | Dermatoendocrinol | pmid:21695018 |
Tsang A et al. | Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. | 2011 | PLoS ONE | pmid:21694781 |
Rossoni LV et al. | Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries. | 2011 | Clin. Sci. | pmid:21671887 |
Maekawa T et al. | Chronic oral infection with Porphyromonas gingivalis accelerates atheroma formation by shifting the lipid profile. | 2011 | PLoS ONE | pmid:21625524 |
Sivy TL et al. | Evidence of isoprenoid precursor toxicity in Bacillus subtilis. | 2011 | Biosci. Biotechnol. Biochem. | pmid:22146731 |
Song JX et al. | Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21052011 |
Tuckow AP et al. | Simvastatin represses protein synthesis in the muscle-derived Câ‚‚Câ‚â‚‚ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:21224482 |
Sawai S and Saito K | Triterpenoid biosynthesis and engineering in plants. | 2011 | Front Plant Sci | pmid:22639586 |
Kim KH et al. | Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants. | 2011 | Drug Metab. Dispos. | pmid:20962060 |
Hong C et al. | Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target. | 2011 | J. Lipid Res. | pmid:21187453 |
Nishikawa Y et al. | Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages. | 2011 | J. Vet. Med. Sci. | pmid:21187676 |
Li YY et al. | Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression. | 2011 | Anticancer Drugs | pmid:20926944 |
Nilsson S et al. | Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells. | 2011 | Cancer Lett. | pmid:21356574 |
Issat T et al. | Antitumor effects of the combination of cholesterol reducing drugs. | 2011 | Oncol. Rep. | pmid:21491092 |
Varman AM et al. | Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae. | 2011 | Microb. Cell Fact. | pmid:21689458 |
Clastre M et al. | Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. | 2011 | Plant Signal Behav | pmid:22080790 |
Castella B et al. | Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. | 2011 | J. Immunol. | pmid:21753152 |
Okada K | The biosynthesis of isoprenoids and the mechanisms regulating it in plants. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21737944 |
Banfi C et al. | Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro. | 2011 | J. Thromb. Haemost. | pmid:21605334 |
Martinez-Moya P et al. | Proteomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous. | 2011 | BMC Microbiol. | pmid:21669001 |
Leichner GS et al. | Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. | 2011 | J. Biol. Chem. | pmid:21778231 |
Simkin AJ et al. | Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta. | 2011 | Planta | pmid:21655959 |
Vallianou I et al. | Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. | 2011 | PLoS ONE | pmid:22073134 |