Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Alvarez De Sotomayor M et al. | Characterization of endothelial factors involved in the vasodilatory effect of simvastatin in aorta and small mesenteric artery of the rat. | 2000 | Br. J. Pharmacol. | pmid:11082126 |
Gregory DH et al. | Mechanism of secretion of biliary lipids. I. Role of bile canalicular and microsomal membranes in the synthesis and transport of biliary lecithin and cholesterol. | 1975 | J. Clin. Invest. | pmid:1109174 |
Palinski W | Immunomodulation: a new role for statins? | 2000 | Nat. Med. | pmid:11100105 |
Jones JP et al. | Rate of sterol formation by rat brain glia and neurons in vitro and in vivo. | 1975 | J. Neurochem. | pmid:1110355 |
pmid:11108295 | ||||
pmid:11111075 | ||||
Hahn FM et al. | 1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. | 2001 | J. Bacteriol. | pmid:11114895 |
Daugherty M et al. | Archaeal shikimate kinase, a new member of the GHMP-kinase family. | 2001 | J. Bacteriol. | pmid:11114929 |
Campos N et al. | Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. | 2001 | Biochem. J. | pmid:11115399 |
Chen H et al. | Fluvastatin upregulates inducible nitric oxide synthase expression in cytokine-stimulated vascular smooth muscle cells. | 2000 | Hypertension | pmid:11116101 |
Asada Y et al. | Biosynthesis of the dimethylallyl moiety of glabrol in Glycyrrhiza glabra hairy root cultures via a non-mevalonate pathway. | 2000 | Phytochemistry | pmid:11117880 |
Fogelman AM et al. | Metabolism of mevalonate in rats and man not leading to sterols. | 1975 | J. Biol. Chem. | pmid:1112830 |
pmid:11133248 | ||||
Ginger ML et al. | The biosynthetic incorporation of the intact leucine skeleton into sterol by the trypanosomatid Leishmania mexicana. | 2001 | J. Biol. Chem. | pmid:11148203 |
Laffitte BA et al. | LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11149950 |
pmid:11150405 | ||||
Luo JD et al. | Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes. | 2001 | Br. J. Pharmacol. | pmid:11156573 |
Kaneda K et al. | An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11158573 |
Dunford JE et al. | Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11160603 |
Reszka AA et al. | Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation. | 2001 | Mol. Pharmacol. | pmid:11160853 |
Alvarez de Sotomayor M and Andriantsitohaina R | Simvastatin and Ca(2+) signaling in endothelial cells: involvement of rho protein. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11162544 |
Kritchevsky D et al. | Experimental atherosclerosis in rabbits fed cholesterol-free diets. 4. Investigation into the source of cholesteremia. | 1975 | Exp. Mol. Pathol. | pmid:1116563 |
Fogelman AM et al. | Abnormal induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in leukocytes from subjects with heterozygous familial hypercholesterolemia. | 1975 | J. Biol. Chem. | pmid:1116997 |
pmid:11170564 | ||||
Eisenreich W et al. | Deoxyxylulose phosphate pathway to terpenoids. | 2001 | Trends Plant Sci. | pmid:11173292 |
GarcÃa-Román N et al. | Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition. | 2001 | Mol. Cell. Neurosci. | pmid:11178870 |
Chiang JY et al. | Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha). | 2001 | Gene | pmid:11179691 |
Gibbons GF and Mitropoulos KA | Effect of trans-1,4-bis(2-chlorobenzylaminomethyl) cyclohexane dihydrochloride and carbon monoxide on hepatic cholesterol biosynthesis from 4,4,-dimethyl sterols in vitro. | 1975 | Biochim. Biophys. Acta | pmid:1120146 |
Dimitroulakos J et al. | Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications. | 2001 | Clin. Cancer Res. | pmid:11205904 |
pmid:11219805 | ||||
pmid:11222952 | ||||
Kovanen PT et al. | Regulation of cholesterol synthesis and storage in fat cells. | 1975 | J. Lipid Res. | pmid:1127358 |
Altincicek B et al. | GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. | 2001 | J. Bacteriol. | pmid:11274098 |
pmid:11275002 | ||||
pmid:11281132 | ||||
Archelas A and Furstoss R | Synthetic applications of epoxide hydrolases. | 2001 | Curr Opin Chem Biol | pmid:11282336 |
Jenkins DJ et al. | Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function. | 2001 | Metab. Clin. Exp. | pmid:11288049 |
Schwender J et al. | Chlorophyta exclusively use the 1-deoxyxylulose 5-phosphate/2-C-methylerythritol 4-phosphate pathway for the biosynthesis of isoprenoids. | 2001 | Planta | pmid:11289606 |
Zhang Z et al. | Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations. | 2001 | J. Lipid Res. | pmid:11290837 |
Blader IJ et al. | Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells. | 2001 | J. Biol. Chem. | pmid:11294868 |
Sapkota GP et al. | Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth. | 2001 | J. Biol. Chem. | pmid:11297520 |
Sharkey TD et al. | Isoprene increases thermotolerance of fosmidomycin-fed leaves. | 2001 | Plant Physiol. | pmid:11299379 |
pmid:11305090 | ||||
Jagdev SP et al. | The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel. | 2001 | Br. J. Cancer | pmid:11308265 |
Houten SM et al. | Organization of the mevalonate kinase (MVK) gene and identification of novel mutations causing mevalonic aciduria and hyperimmunoglobulinaemia D and periodic fever syndrome. | 2001 | Eur. J. Hum. Genet. | pmid:11313768 |
Skaletz-Rorowski A et al. | Lovastatin blocks basic fibroblast growth factor-induced mitogen-activated protein kinase signaling in coronary smooth muscle cells via phosphatase inhibition. | 2001 | Eur. J. Cell Biol. | pmid:11322384 |
Takemoto M et al. | NK-104, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, reduces osteopontin expression by rat aortic smooth muscle cells. | 2001 | Br. J. Pharmacol. | pmid:11325797 |
pmid:11336263 | ||||
MartÃnez-González J et al. | 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation. | 2001 | Arterioscler. Thromb. Vasc. Biol. | pmid:11348878 |
O'Neill FH et al. | Determinants of variable response to statin treatment in patients with refractory familial hypercholesterolemia. | 2001 | Arterioscler. Thromb. Vasc. Biol. | pmid:11348882 |