Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Pomerantz KB et al. | G-protein-mediated signaling in cholesterol-enriched arterial smooth muscle cells. 2. Role of protein kinase C-delta in the regulation of eicosanoid production. | 1997 | Biochemistry | pmid:9235999 |
Paton VG et al. | Cloning and subcellular localization of hamster and rat isopentenyl diphosphate dimethylallyl diphosphate isomerase. A PTS1 motif targets the enzyme to peroxisomes. | 1997 | J. Biol. Chem. | pmid:9228075 |
pmid:9226547 | ||||
Flint OP et al. | HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgeranylation of low-molecular-weight proteins in neonatal rat muscle cell culture. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9221829 |
Flint OP et al. | Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9221828 |
Lasa M et al. | Lovastatin decreases prolactin and growth hormone gene expression in GH4C1 cells through a cAMP dependent mechanism. | 1997 | Mol. Cell. Endocrinol. | pmid:9220025 |
pmid:921298 | ||||
Spencer TA et al. | Feasibility of an immunoassay for mevalonolactone. | 1997 | Bioorg. Med. Chem. | pmid:9208099 |
Chan PC et al. | Lovastatin increases surface low density lipoprotein receptor expression by retarding the receptor internalization rate in proliferating lymphocytes. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9196047 |
pmid:9191394 | ||||
Raiteri M et al. | Pharmacological control of the mevalonate pathway: effect on arterial smooth muscle cell proliferation. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9190847 |
Fuhrman B et al. | Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9168909 |
He L et al. | Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo. | 1997 | J. Nutr. | pmid:9164984 |
Amin D et al. | RPR 107393, a potent squalene synthase inhibitor and orally effective cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9152381 |
Anouja F et al. | The cytotoxicity of the parvovirus minute virus of mice nonstructural protein NS1 is related to changes in the synthesis and phosphorylation of cell proteins. | 1997 | J. Virol. | pmid:9151861 |
Herawati E and Ishizaki A | Optimization of the culture medium for growth and the kinetics of lactate fermentation by Pediococcus sp. ISK-1. | 1997 | Biosci. Biotechnol. Biochem. | pmid:9145518 |
Padayatty SJ et al. | Lovastatin-induced apoptosis in prostate stromal cells. | 1997 | J. Clin. Endocrinol. Metab. | pmid:9141529 |
Tamai I et al. | Intestinal brush-border membrane transport of monocarboxylic acids mediated by proton-coupled transport and anion antiport mechanisms. | 1997 | J. Pharm. Pharmacol. | pmid:9120761 |
Sinensky M | Isolation of a mammalian cell mutant resistant to 25-hydroxy cholesterol. | 1977 | Biochem. Biophys. Res. Commun. | pmid:911332 |
Khan SA and Nyce JW | Effects of ubiquinone and mevalonic acid on hepatic peroxisomal enzymes induced by dehydroepiandrosterone. | 1997 | Pharmacol. Toxicol. | pmid:9101583 |
Cartwright IJ et al. | Investigation of the role of lipids in the assembly of very low density lipoproteins in rabbit hepatocytes. | 1997 | J. Lipid Res. | pmid:9101434 |
pmid:9089010 | ||||
Crick DC et al. | Geranylgeraniol promotes entry of UT-2 cells into the cell cycle in the absence of mevalonate. | 1997 | Exp. Cell Res. | pmid:9087171 |
Endo A et al. | Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1977 | Eur. J. Biochem. | pmid:908337 |
Colli S et al. | Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis. | 1997 | Arterioscler. Thromb. Vasc. Biol. | pmid:9081680 |
pmid:9070894 | ||||
Scoppola A et al. | Plasma mevalonate concentrations in uremic patients. | 1997 | Kidney Int. | pmid:9067929 |
pmid:9056235 | ||||
BeytÃa ED and Porter JW | Biochemistry of polyisoprenoid biosynthesis. | 1976 | Annu. Rev. Biochem. | pmid:9026 |
Edwards PA et al. | Preferential uptake and utilization of mevalonolactone over mevalonate for sterol biosynthesis in isolated rat hepatocytes. | 1977 | Biochim. Biophys. Acta | pmid:901801 |
Peffley DM and Gayen AK | Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level. | 1997 | Arch. Biochem. Biophys. | pmid:9016820 |
Stout RW | The effect of insulin and glucose on sterol synthesis in cultured rat arterial smooth muscle cells. | 1977 | Atherosclerosis | pmid:901624 |
Lichtenthaler HK et al. | Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. | 1997 | FEBS Lett. | pmid:9009212 |
pmid:900481 | ||||
Chiloeches A et al. | Effect of mevalonate availability on the association of G-protein alpha-subunits with the plasma membrane in GH4C1 cells. | 1997 | FEBS Lett. | pmid:9003808 |
Hirai A et al. | Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells. | 1997 | J. Biol. Chem. | pmid:8995216 |
Spicer LJ et al. | Insulin-like growth factor I enhancement of steroidogenesis by bovine granulosa cells and thecal cells: dependence on de novo cholesterol synthesis. | 1996 | J. Endocrinol. | pmid:8994382 |
Krisans SK | Cell compartmentalization of cholesterol biosynthesis. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8993542 |
Shoda J et al. | Simultaneous determination of plasma mevalonate and 7alpha-hydroxy-4-cholesten-3-one levels in hyperlipoproteinemia: convenient indices for estimating hepatic defects of cholesterol and bile acid syntheses and biliary cholesterol supersaturation. | 1997 | Hepatology | pmid:8985259 |
Sato-Suzuki I and Murota S | Simvastatin inhibits the division and induces neurite-like outgrowth in PC12 cells. | 1996 | Neurosci. Lett. | pmid:8977139 |
Bandoh T et al. | Inhibitory effect of fluvastatin at doses insufficient to lower serum lipids on the catheter-induced thickening of intima in rabbit femoral artery. | 1996 | Eur. J. Pharmacol. | pmid:8960862 |
pmid:8957210 | ||||
pmid:8946387 | ||||
Field H et al. | Characterisation of protein isoprenylation in procyclic form Trypanosoma brucei. | 1996 | Mol. Biochem. Parasitol. | pmid:8943151 |
Goalstone ML and Draznin B | Effect of insulin on farnesyltransferase activity in 3T3-L1 adipocytes. | 1996 | J. Biol. Chem. | pmid:8910345 |
Umetani N et al. | Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages. | 1996 | Biochim. Biophys. Acta | pmid:8908154 |
pmid:8907210 | ||||
Lindenthal B et al. | Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis. | 1996 | J. Lipid Res. | pmid:8906596 |
pmid:8902853 | ||||
Ramsey RB and Fredericks M | Effect of hypocholesterolemic agents on central nervous system cholesterol biosynthesis. I. Zuclomiphene. | 1977 | Biochem. Pharmacol. | pmid:889582 |