Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Alonso-Gutierrez J et al. | Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production. | 2013 | Metab. Eng. | pmid:23727191 |
Theesfeld CL and Hampton RY | Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast. | 2013 | J. Biol. Chem. | pmid:23306196 |
van der Burgh R et al. | Mevalonate kinase deficiency, a metabolic autoinflammatory disease. | 2013 | Clin. Immunol. | pmid:23110805 |
Hosaka A et al. | Statins reduce amyloid β-peptide production by modulating amyloid precursor protein maturation and phosphorylation through a cholesterol-independent mechanism in cultured neurons. | 2013 | Neurochem. Res. | pmid:23269484 |
Tricarico PM et al. | Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study. | 2013 | Biomed Res Int | pmid:24073415 |
MartÃn-Navarro CM et al. | Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections. | 2013 | Antimicrob. Agents Chemother. | pmid:23114753 |
Zhang J et al. | Statins directly suppress cytokine production in murine intraepithelial lymphocytes. | 2013 | Cytokine | pmid:23290865 |
Rauthan M et al. | The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23530189 |
Citron CA and Dickschat JS | The stereochemical course of tricho-acorenol biosynthesis. | 2013 | Org. Biomol. Chem. | pmid:24084795 |
Blanc M et al. | The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. | 2013 | Immunity | pmid:23273843 |
Wang C et al. | Engineered heterologous FPP synthases-mediated Z,E-FPP synthesis in E. coli. | 2013 | Metab. Eng. | pmid:23608473 |
Yu W et al. | The mevalonate auxotrophic mutant of Staphylococcus aureus can adapt to mevalonate depletion. | 2013 | Antimicrob. Agents Chemother. | pmid:23959312 |
Szűcs G et al. | Cardioprotection by farnesol: role of the mevalonate pathway. | 2013 | Cardiovasc Drugs Ther | pmid:23673412 |
Ramak P et al. | Inhibition of the mevalonate pathway enhances carvacrol biosynthesis and DXR gene expression in shoot cultures of Satureja khuzistanica Jamzad. | 2013 | J. Plant Physiol. | pmid:23611428 |
Chen X et al. | Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. | 2013 | PLoS ONE | pmid:24278153 |
Chang WC et al. | Current development in isoprenoid precursor biosynthesis and regulation. | 2013 | Curr Opin Chem Biol | pmid:23891475 |
Tuerdi G et al. | Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells. | 2013 | Cancer Lett. | pmid:23879968 |
Gopalan A et al. | Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway. | 2013 | Cancer Lett. | pmid:22960596 |
Onono F et al. | Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. | 2013 | J. Biol. Chem. | pmid:23908355 |
Gopalan A et al. | Eliminating drug resistant breast cancer stem-like cells with combination of simvastatin and gamma-tocotrienol. | 2013 | Cancer Lett. | pmid:23063651 |
Liu J et al. | Overproduction of geraniol by enhanced precursor supply in Saccharomyces cerevisiae. | 2013 | J. Biotechnol. | pmid:24161921 |
Lee SK and Kim YS | Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria. | 2013 | Int. J. Oncol. | pmid:23354132 |
Valente AJ et al. | Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin. | 2013 | Cell. Signal. | pmid:23541442 |
Xiao H et al. | Inhibition of Rho and Rac geranylgeranylation by atorvastatin is critical for preservation of endothelial junction integrity. | 2013 | PLoS ONE | pmid:23555637 |
Villanueva JA et al. | Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells. | 2013 | J. Clin. Endocrinol. Metab. | pmid:23386644 |
May B et al. | Biosynthesis of sesquiterpenes in grape berry exocarp of Vitis vinifera L.: evidence for a transport of farnesyl diphosphate precursors from plastids to the cytosol. | 2013 | Phytochemistry | pmid:23954075 |
Zeng H et al. | mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function. | 2013 | Nature | pmid:23812589 |
Bruzzese F et al. | Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways. | 2013 | Cell Death Dis | pmid:24157872 |
Dick M et al. | Statin therapy influences endothelial cell morphology and F-actin cytoskeleton structure when exposed to static and laminar shear stress conditions. | 2013 | Life Sci. | pmid:23517776 |
Fang SY et al. | Pleiotropic vascular protective effects of statins in perioperative medicine. | 2013 | Acta Anaesthesiol Taiwan | pmid:24148741 |
Maciejak A et al. | The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase. | 2013 | BMC Biotechnol. | pmid:24128347 |
Polidoro S et al. | Effects of bisphosphonate treatment on DNA methylation in osteonecrosis of the jaw. | 2013 | Mutat. Res. | pmid:23892139 |
Santolaria T et al. | Repeated systemic administrations of both aminobisphosphonates and human Vγ9Vδ2 T cells efficiently control tumor development in vivo. | 2013 | J. Immunol. | pmid:23836057 |
Poggi A et al. | Selective role of mevalonate pathway in regulating perforin but not FasL and TNFalpha release in human Natural Killer cells. | 2013 | PLoS ONE | pmid:23667543 |
Ohukainen P | If the wheel ain't broke, don't reinvent it. | 2013 | Lipids Health Dis | pmid:23577775 |
Werner M et al. | Simvastatin-induced compartmentalisation of doxorubicin sharpens up nuclear topoisomerase II inhibition in human rhabdomyosarcoma cells. | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23564041 |
Zhu Y et al. | Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases. | 2013 | Cell Death Dis | pmid:23559002 |
Lee NY and Kang YS | The effects of bisphosphonates on taurine transport in retinal capillary endothelial cells under high glucose conditions. | 2013 | Adv. Exp. Med. Biol. | pmid:23392871 |
Corcos L and Le Jossic-Corcos C | Statins: perspectives in cancer therapeutics. | 2013 | Dig Liver Dis | pmid:23490341 |
Doblas VG et al. | The SUD1 gene encodes a putative E3 ubiquitin ligase and is a positive regulator of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in Arabidopsis. | 2013 | Plant Cell | pmid:23404890 |
Riganti C et al. | Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. | 2013 | PLoS ONE | pmid:23593363 |
Lazzerini PE et al. | Rosuvastatin inhibits spontaneous and IL-1β-induced interleukin-6 production from human cultured osteoblastic cells. | 2013 | Joint Bone Spine | pmid:22999910 |
Mazein A et al. | A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway. | 2013 | Biochem. Pharmacol. | pmid:23583456 |
Hong SY et al. | Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. | 2012 | J. Appl. Microbiol. | pmid:22519412 |
Iwata A et al. | Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. | 2012 | Clin. Exp. Immunol. | pmid:22471285 |
Luvai A et al. | Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. | 2012 | Clin Med Insights Cardiol | pmid:22442638 |
Lachenmeier DW et al. | NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements. | 2012 | Chin Med | pmid:22439629 |
Murphy LA et al. | Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22361350 |
Fuhrmeister J et al. | Prooxidative toxicity and selenoprotein suppression by cerivastatin in muscle cells. | 2012 | Toxicol. Lett. | pmid:23092657 |
Khasnavis S and Pahan K | Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. | 2012 | J Neuroimmune Pharmacol | pmid:21701815 |