Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Biliary Fistula D001658 13 associated lipids
Body Weight D001835 333 associated lipids
Celiac Disease D002446 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Hypertension D006973 115 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia D007938 74 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Peutz-Jeghers Syndrome D010580 2 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Refsum Disease D012035 19 associated lipids
Thrombosis D013927 49 associated lipids
Xanthomatosis D014973 17 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Wang H et al. Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. 2011 J. Immunol. pmid:22013129
Ali OF et al. Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. 2011 Respir. Res. pmid:21999923
Scheller EL et al. Bisphosphonates inhibit expression of p63 by oral keratinocytes. 2011 J. Dent. Res. pmid:21551338
Kishi T Mevalonate pathway is a novel target for hypertension. 2011 Circ. J. pmid:21532185
Brock NL et al. Biosynthesis of sesqui- and diterpenes by the gibberellin producer Fusarium fujikuroi. 2011 Chembiochem pmid:21990128
Cluis CP et al. Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). 2011 Metab. Eng. pmid:21986057
Kimachi K et al. Zoledronic acid inhibits RANK expression and migration of osteoclast precursors during osteoclastogenesis. 2011 Naunyn Schmiedebergs Arch. Pharmacol. pmid:21225243
Epplen R et al. Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. 2011 Acta Oncol pmid:20429730
Soto G et al. Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation. 2011 J. Exp. Bot. pmid:21908473
Barta ML et al. Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. 2011 J. Biol. Chem. pmid:21561869
Maki KC et al. Effects of soy protein on lipoprotein lipids and fecal bile acid excretion in men and women with moderate hypercholesterolemia. 2010 Nov-Dec J Clin Lipidol pmid:21122701
Camps D [Controversies regarding the use of statins in the acute coronary syndrome]. 2010 Aug-Sep Med Intensiva pmid:20538377
Omar SH Oleuropein in olive and its pharmacological effects. 2010 Apr-Jun Sci Pharm pmid:21179340
Morrone D et al. Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. 2010 Appl. Microbiol. Biotechnol. pmid:19777230
Fukunaga M et al. Mast cell death induced by 24(S),25-epoxycholesterol. 2010 Exp. Cell Res. pmid:20854813
Bouvier-Navé P et al. Involvement of the phospholipid sterol acyltransferase1 in plant sterol homeostasis and leaf senescence. 2010 Plant Physiol. pmid:19923239
Honour JW Steroid assays in paediatric endocrinology. 2010 J Clin Res Pediatr Endocrinol pmid:21274330
Head BP et al. Loss of caveolin-1 accelerates neurodegeneration and aging. 2010 PLoS ONE pmid:21203469
Guella G et al. Structures, biological activities and phylogenetic relationships of terpenoids from marine ciliates of the genus Euplotes. 2010 Mar Drugs pmid:20714425
Jana S and Shekhawat GS Anethum graveolens: An Indian traditional medicinal herb and spice. 2010 Pharmacogn Rev pmid:22228959
Zheng Z et al. Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome proliferator-activated receptor gamma coactivator 1alpha. 2010 Diabetes pmid:20566666
Liu Q et al. Dynamics of lamin-A processing following precursor accumulation. 2010 PLoS ONE pmid:20526372
Aoyama T et al. Pharmacokinetic/pharmacodynamic modeling and simulation of rosuvastatin using an extension of the indirect response model by incorporating a circadian rhythm. 2010 Biol. Pharm. Bull. pmid:20522984
Jameson JM et al. A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes. 2010 Cell. Immunol. pmid:20483407
Hughes M et al. Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP. 2010 J. Neurochem. pmid:20477946
Targett-Adams P et al. Lipid metabolism and HCV infection. 2010 Viruses pmid:21994676
Snoeren TA et al. The herbivore-induced plant volatile methyl salicylate negatively affects attraction of the parasitoid Diadegma semiclausum. 2010 J. Chem. Ecol. pmid:20407809
Lefurgy ST et al. Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae. 2010 J. Biol. Chem. pmid:20404339
Clendening JW et al. Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma. 2010 Blood pmid:20360469
Yang Z et al. Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. 2010 Int. J. Cancer pmid:19626588
Domoki F et al. Rosuvastatin induces delayed preconditioning against L-glutamate excitotoxicity in cultured cortical neurons. 2010 Neurochem. Int. pmid:19931334
De Leo L et al. Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches. 2010 Pharmacol. Res. pmid:20206266
Tisch D and Schmoll M Light regulation of metabolic pathways in fungi. 2010 Appl. Microbiol. Biotechnol. pmid:19915832
Coscia M et al. Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. 2010 J. Cell. Mol. Med. pmid:19818098
Massaro M et al. Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability. 2010 Cardiovasc. Res. pmid:19946014
Kojima Y et al. Pitavastatin decreases the expression of endothelial lipase both in vitro and in vivo. 2010 Cardiovasc. Res. pmid:20045866
Liu YJ et al. Simvastatin ameliorates rat cerebrovascular remodeling during hypertension via inhibition of volume-regulated chloride channel. 2010 Hypertension pmid:20644009
Kones R Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. 2010 Drug Des Devel Ther pmid:21267417
Hooff GP et al. Isoprenoids, small GTPases and Alzheimer's disease. 2010 Biochim. Biophys. Acta pmid:20382260
Mitrofan LM et al. Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. 2010 J. Biol. Chem. pmid:19875454
Rossi J et al. Laminar shear stress prevents simvastatin-induced adhesion molecule expression in cytokine activated endothelial cells. 2010 Eur. J. Pharmacol. pmid:20863785
Kaneda T et al. Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells. 2010 Eur. J. Pharmacol. pmid:20851116
Kassan M et al. In vitro antioxidant activity of pravastatin provides vascular protection. 2010 Eur. J. Pharmacol. pmid:20044990
Kocsis GF et al. Expression of genes related to oxidative/nitrosative stress in mouse hearts: effect of preconditioning and cholesterol diet. 2010 Med. Sci. Monit. pmid:20037483
Endo A A historical perspective on the discovery of statins. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20467214
Clendening JW et al. Dysregulation of the mevalonate pathway promotes transformation. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20696928
Woo IS et al. Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. 2010 Neurosci. Lett. pmid:20298756
Asadollahi MA et al. Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. 2010 Biotechnol. Bioeng. pmid:20091767
Lee SK et al. Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. 2010 Biochem. Biophys. Res. Commun. pmid:20043868
Huang M et al. Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. 2010 Plant Physiol. pmid:20463089