Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
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There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
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We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
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All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ruiz-Sola MÃ et al. | A Single Arabidopsis Gene Encodes Two Differentially Targeted Geranylgeranyl Diphosphate Synthase Isoforms. | 2016 | Plant Physiol. | pmid:27707890 |
| Jiang Z et al. | Engineering Triterpene and Methylated Triterpene Production in Plants Provides Biochemical and Physiological Insights into Terpene Metabolism. | 2016 | Plant Physiol. | pmid:26603654 |
| Mertens J et al. | The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula. | 2016 | Plant Physiol. | pmid:26589673 |
| Yildirim FI et al. | Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. | 2015 | Prostaglandins Other Lipid Mediat. | pmid:26201058 |
| Surup F et al. | Deconins A-E: Cuparenic and Mevalonic or Propionic Acid Conjugates from the Basidiomycete Deconica sp. 471. | 2015 | J. Nat. Prod. | pmid:25871540 |
| York AG et al. | Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. | 2015 | Cell | pmid:26686653 |
| Miettinen TP and Björklund M | Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy. | 2015 | Cell Rep | pmid:26686643 |
| Gallagher KA and Jensen PR | Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade. | 2015 | BMC Genomics | pmid:26578069 |
| Nyati P et al. | Negative Feedbacks by Isoprenoids on a Mevalonate Kinase Expressed in the Corpora Allata of Mosquitoes. | 2015 | PLoS ONE | pmid:26566274 |
| Chen Y et al. | Mevalonate inhibits acid sphingomyelinase activity, increases sphingomyelin levels and inhibits cell proliferation of HepG2 and Caco-2 cells. | 2015 | Lipids Health Dis | pmid:26493087 |
| Laezza C et al. | p53 regulates the mevalonate pathway in human glioblastoma multiforme. | 2015 | Cell Death Dis | pmid:26469958 |
| Rondini EA et al. | Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes. | 2015 | J. Pharmacol. Exp. Ther. | pmid:26427720 |
| Guan Z et al. | Metabolic engineering of Bacillus subtilis for terpenoid production. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26373726 |
| Pandyra AA et al. | Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death. | 2015 | Oncotarget | pmid:26353928 |
| Kuo KK et al. | Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss. | 2015 | J. Lipid Res. | pmid:26351364 |
| Kain V et al. | Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism. | 2015 | Sci Rep | pmid:26345110 |
| Henry LK et al. | Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26216978 |
| Zhang Z et al. | Genomic variations of the mevalonate pathway in porokeratosis. | 2015 | Elife | pmid:26202976 |
| Venkateshwaran M et al. | A role for the mevalonate pathway in early plant symbiotic signaling. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26199419 |
| Tricarico PM et al. | Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link. | 2015 | Int J Mol Sci | pmid:26184189 |
| Kobayashi Y et al. | Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models. | 2015 | Clin. Cancer Res. | pmid:26109099 |
| Tricarico PM et al. | Alendronate, a double-edged sword acting in the mevalonate pathway. | 2015 | Mol Med Rep | pmid:26096667 |
| Hofberger JA et al. | Large-Scale Evolutionary Analysis of Genes and Supergene Clusters from Terpenoid Modular Pathways Provides Insights into Metabolic Diversification in Flowering Plants. | 2015 | PLoS ONE | pmid:26046541 |
| Karlic H et al. | Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells. | 2015 | Cancer Genet | pmid:25978957 |
| Zhou X et al. | Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation. | 2015 | Mol Med Rep | pmid:25936991 |
| Du X et al. | Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots. | 2015 | Molecules | pmid:25919278 |
| Chen GP et al. | Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process. | 2015 | J Diabetes Res | pmid:25918730 |
| Sharon C et al. | Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. | 2015 | Oncotarget | pmid:25895029 |
| Hwang HS et al. | Transcriptomic analysis of Siberian ginseng (Eleutherococcus senticosus) to discover genes involved in saponin biosynthesis. | 2015 | BMC Genomics | pmid:25888223 |
| Hirota Y et al. | Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1. | 2015 | PLoS ONE | pmid:25874989 |
| Autefage H et al. | Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25831522 |
| Wang WQ et al. | Proteomic analysis of lettuce seed germination and thermoinhibition by sampling of individual seeds at germination and removal of storage proteins by polyethylene glycol fractionation. | 2015 | Plant Physiol. | pmid:25736209 |
| Sekiya A et al. | Fluvastatin Upregulates the Expression of Tissue Factor Pathway Inhibitor in Human Umbilical Vein Endothelial Cells. | 2015 | J. Atheroscler. Thromb. | pmid:25735397 |
| Polotskaia A et al. | Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25733866 |
| de Oliveira LS et al. | New Insights on the terpenome of the red seaweed Laurencia dendroidea (Florideophyceae, Rhodophyta). | 2015 | Mar Drugs | pmid:25675000 |
| Rossoni L et al. | The Putative mevalonate diphosphate decarboxylase from Picrophilus torridus is in reality a mevalonate-3-kinase with high potential for bioproduction of isobutene. | 2015 | Appl. Environ. Microbiol. | pmid:25636853 |
| Skaff DA et al. | Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds. | 2015 | Arch. Biochem. Biophys. | pmid:25499551 |
| Kang S et al. | Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. | 2015 | Eur J Med Chem | pmid:25461893 |
| Matsuo S et al. | Single-dose rosuvastatin ameliorates lung ischemia-reperfusion injury via upregulation of endothelial nitric oxide synthase and inhibition of macrophage infiltration in rats with pulmonary hypertension. | 2015 | J. Thorac. Cardiovasc. Surg. | pmid:25454916 |
| Vinokur JM et al. | Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. | 2015 | Protein Sci. | pmid:25422158 |
| Greife A et al. | Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation. | 2015 | Tumour Biol. | pmid:25566959 |
| Khandelwal VK et al. | Oxidative stress plays an important role in zoledronic acid-induced autophagy. | 2014 | Physiol Res | pmid:25669691 |
| Warita K et al. | Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. | 2014 | Sci Rep | pmid:25534349 |
| Piłsyk S et al. | Overexpression of erg20 gene encoding farnesyl pyrophosphate synthase has contrasting effects on activity of enzymes of the dolichyl and sterol branches of mevalonate pathway in Trichoderma reesei. | 2014 | Gene | pmid:24793581 |
| Ghavami S et al. | Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins. | 2014 | Biochim. Biophys. Acta | pmid:24637330 |
| Korman TP et al. | A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates. | 2014 | Protein Sci. | pmid:24623472 |
| Yeganeh B et al. | Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. | 2014 | Pharmacol. Ther. | pmid:24582968 |
| Rojo-Arreola L et al. | Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis. | 2014 | PLoS ONE | pmid:24489942 |
| Fu Z et al. | Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process. | 2014 | Microb. Cell Fact. | pmid:24593159 |
| Rachner TD et al. | Dickkopf-1 is regulated by the mevalonate pathway in breast cancer. | 2014 | Breast Cancer Res. | pmid:24528599 |