Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Brunengraber H et al. | Urinary clearance and metabolism of mevalonate by the isolataed perfused rat kidney. | 1981 | J. Lipid Res. | pmid:7276751 |
Humphries GM | Difference in the ability of compactin and oxidized cholesterol, both known inhibitors of cholesterol biosynthesis, to suppress in vitro immune responses. | 1981 | Cancer Res. | pmid:7260948 |
Ryan J et al. | Isolation and characterization of cells resistant to ML236B (compactin) with increased levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1981 | J. Biol. Chem. | pmid:7240242 |
pmid:7236655 | ||||
Hagler WM et al. | Biosynthesis of radiolabeled T-2 toxin by Fusarium tricinctum. | 1981 | Appl. Environ. Microbiol. | pmid:7235702 |
Stange EF et al. | Regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by endogenous sterol synthesis in cultured intestinal mucosa. | 1981 | Biochim. Biophys. Acta | pmid:7225401 |
Stange EF et al. | Influence of dietary cholesterol, saturated and unsaturated lipid on 3-hydroxy-3-methylglutaryl CoA reductase activity in rabbit intestine and liver. | 1981 | J. Lipid Res. | pmid:7217785 |
pmid:7212258 | ||||
Sable-Amplis R et al. | Abnormal liver cholesteryl ester storage in a strain of golden hamsters. Possible model for studies on cholesterol metabolism. | 1978 | Biochim. Biophys. Acta | pmid:718971 |
Allen KG and Klevay LM | Copper deficiency and cholesterol metabolism in the rat. | 1978 | Atherosclerosis | pmid:718736 |
Nes WD et al. | Metabolism of mevalonic acid to long chain fatty alcohols in an insect. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181890 |
Sablé-Amplis R and Sicart R | Evidence for negative feedback control of cholesterogenesis from mevalonate in liver: absence in the intestine of guinea pigs fed a 0.5% cholesterol diet. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181883 |
Greenwood DR and Rees HH | Mechanism of hydroxylation at C-22 during the biosynthesis of ecdysteroids in the locust Schistocerca gregaria. | 1982 | Biochem. J. | pmid:7165737 |
Masuda A et al. | Chinese hamster cell mutant resistant to ML236B (Compactin) is defective in endocytosis of low-density lipo-protein. | 1982 | Mol. Cell. Biol. | pmid:7162516 |
Ekström T et al. | Biosynthesis of dolichol and dolichylphosphate in rat hepatocytes in vivo. | 1982 | FEBS Lett. | pmid:7160467 |
pmid:7159436 | ||||
pmid:7151179 | ||||
Ranganathan S et al. | Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts. | 1982 | Atherosclerosis | pmid:7150392 |
Schmidt RA et al. | A study of the Influence of mevalonic acid and its metabolites on the morphology of swiss 3T3 cells. | 1982 | J. Cell Biol. | pmid:7142283 |
Lovati MR et al. | Cholesterol and bile-acid metabolism in normal and cholesterol-fed rabbits after partial ileal bypass. | 1982 | Exp. Mol. Pathol. | pmid:7140933 |
Nestel PJ et al. | The effect of dietary fat supplements on cholesterol metabolism in ruminants. | 1978 | J. Lipid Res. | pmid:712248 |
Linder JR and Beitz DC | Sterol synthesis and CO2 production from mevalonate in calves. | 1978 | J. Lipid Res. | pmid:712243 |
Angelin B et al. | Hepatic cholesterol metabolism in obesity: activity of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1982 | J. Lipid Res. | pmid:7119574 |
Schwartz CC et al. | Multicompartmental analysis of cholesterol metabolism in man. Quantitative kinetic evaluation of precursor sources and turnover of high density lipoprotein cholesterol esters. | 1982 | J. Clin. Invest. | pmid:7119117 |
Kleist H et al. | Metabolism in the hypothermically perfused kidney: utilization of mevalonate in the human and in the dog kidney. | 1982 | Eur Surg Res | pmid:7117329 |
Cohen DC et al. | Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in vascular endothelial cells. Separate sterol and non-sterol components. | 1982 | J. Biol. Chem. | pmid:7107647 |
Tilvis R et al. | Metabolism of squalene in human fat cells. Demonstration of a two-pool system. | 1982 | J. Biol. Chem. | pmid:7107606 |
Wilson WK et al. | Determination of the enantiomeric purity of mevalonolactone via NMR using a chiral lanthanide shift reagent. | 1982 | J. Lipid Res. | pmid:7097129 |
Kopito RR et al. | Metabolism of plasma mevalonate in rats and humans. | 1982 | J. Lipid Res. | pmid:7097123 |
Sinensky M et al. | Analysis of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in a somatic cell mutant auxotrophic for mevalonate. | 1982 | J. Biol. Chem. | pmid:7085625 |
Golper TA and Swartz SH | Impaired renal mevalonate metabolism in nephrotic syndrome: a stimulus for increased hepatic cholesterogenesis independent of GFR and hypoalbuminemia. | 1982 | Metab. Clin. Exp. | pmid:7078427 |
pmid:707796 | ||||
Wong TK and Lennarz WJ | The site of biosynthesis and intracellular deposition of dolichol in rat liver. | 1982 | J. Biol. Chem. | pmid:7076684 |
Volpe JJ and Obert KA | Interrelationships of ubiquinone and sterol syntheses in cultured cells of neural origin. | 1982 | J. Neurochem. | pmid:7062041 |
Poznansky MJ and Czekanski S | Cholesterol movement between human skin fibroblasts and phosphatidylcholine vesicles. | 1982 | Biochim. Biophys. Acta | pmid:7059600 |
Pratt HP | Preimplantation mouse embryos synthesize membrane sterols. | 1982 | Dev. Biol. | pmid:7054002 |
Fears R | The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function. | 1981 | Biochem. J. | pmid:7039614 |
Bard M and Downing JF | Genetic and biochemical aspects of yeast sterol regulation involving 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1981 | J. Gen. Microbiol. | pmid:7033470 |
Swift IE and Milborrow BV | Stereochemistry of beta-, gamma-, and epsilon-ring formation in bacterial C50. | 1981 | J. Biol. Chem. | pmid:7028738 |
Schroepfer GJ | Sterol biosynthesis. | 1981 | Annu. Rev. Biochem. | pmid:7023367 |
Ramsey RB and Fredericks M | Effect of hypocholesterolemic agents on central nervous system cholesterol biosynthesis. II. AY-9944 and AY-9944 plus zuclomiphene. | 1977 | Biochem. Pharmacol. | pmid:70208 |
Middleton B et al. | The control of sterol synthesis during development of rabbit mammary gland. | 1981 | J. Biol. Chem. | pmid:7014559 |
Brown MS and Goldstein JL | Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. | 1980 | J. Lipid Res. | pmid:6995544 |
Cuthbert JA and Lipsky PE | Sterol metabolism and lymphocyte function: inhibition of endogenous sterol biosynthesis does not prevent mitogen-induced human T lymphocyte activation. | 1980 | J. Immunol. | pmid:6965969 |
Pullinger CR and Gibbons GF | Effects of oleate and compactin on the metabolism and secretion of cholesterol and cholesteryl ester by rat hepatocytes. | 1982 | Biochim. Biophys. Acta | pmid:6960928 |
Parker TS et al. | Mevalonic acid in human plasma: relationship of concentration and circadian rhythm to cholesterol synthesis rates in man. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953446 |
Larson RA et al. | Neutrophils are required for the DNA synthetic response of human lymphocytes to mevalonic acid: evidence suggesting that a nonsterol product of mevalonate is involved. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953445 |
Schwartz CC et al. | Central role of high density lipoprotein in plasma free cholesterol metabolism. | 1982 | J. Clin. Invest. | pmid:6953075 |
Arebalo RE et al. | In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: immunotitration of the enzyme after short-term mevalonate or cholesterol feeding. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6948302 |
Sinensky M et al. | Somatic cell genetic analysis of regulation of expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6935672 |
Huneeus VQ et al. | Isopentenyladenine as a mediator of mevalonate-regulated DNA replication. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6934516 |
Kita T et al. | Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. | 1980 | J. Clin. Invest. | pmid:6903572 |
Menon AS et al. | Vanadate inhibits mevalonate synthesis and activates NADH oxidation in microsomes. | 1980 | FEBS Lett. | pmid:6900565 |
Surani MA et al. | Mevalonate reverses the developmental arrest of preimplantation mouse embryos by Compactin, an inhibitor of HMG Co A reductase. | 1983 | J Embryol Exp Morphol | pmid:6886611 |
Mitropoulos KA et al. | On the mechanism for the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, of cholesterol 7alpha-hydroxylase and of acyl-coenzyme A:cholesterol acyltransferase by free cholesterol. | 1978 | Biochim. Biophys. Acta | pmid:687657 |
Parker TS et al. | Inhibition of liver prenyltransferase by alkyl phosphonates and phosphonophosphates. | 1978 | Biochim. Biophys. Acta | pmid:687653 |
Suckling KE et al. | In vivo modulation of rat liver acyl-coenzyme A:cholesterol acyltransferase by phosphorylation and substrate supply. | 1983 | FEBS Lett. | pmid:6873300 |
Edwards PA et al. | Mevalonolactone inhibits the rate of synthesis and enhances the rate of degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in rat hepatocytes. | 1983 | J. Biol. Chem. | pmid:6863245 |
Thompson JS et al. | Morphologic and biochemical changes in dogs after portacaval shunt plus bile fistula or ileal bypass: failure of bile fistula or ileal bypass to prevent hepatocyte atrophy. | 1983 Jul-Aug | Hepatology | pmid:6862371 |
Quesney-Huneeus V et al. | The dual role of mevalonate in the cell cycle. | 1983 | J. Biol. Chem. | pmid:6848509 |
pmid:6838508 | ||||
Sprott GD et al. | Isolation and chemical composition of the cytoplasmic membrane of the archaebacterium Methanospirillum hungatei. | 1983 | J. Biol. Chem. | pmid:6833242 |
Hoffman PC et al. | Cholesterol and mevalonic acid are independent requirements for the in vitro proliferation of human bone marrow granulocyte progenitor cells: studies using ML-236B. | 1983 | Blood | pmid:6831033 |
Melnykovych G and Clowes KK | Suppression of glucocorticoid-induced elevation of alkaline phosphatase in C-4-1 cells by inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and reversal of the suppression by mevalonate. | 1983 | Biochim. Biophys. Acta | pmid:6830849 |
pmid:6827993 | ||||
Brady PS et al. | Evidence for an underestimation of the shunt pathway of mevalonate metabolism in slices of livers and kidneys from fasted rats and rats in diabetic ketosis. | 1982 | J. Lipid Res. | pmid:6819335 |
Brady PS et al. | The tracing of the pathway of mevalonate's metabolism to other than sterols. | 1982 | J. Biol. Chem. | pmid:6809755 |
Kling D and Gamble W | Cholesterol biosynthesis in polychlorinated biphenyl-treated rats. | 1982 | Environ. Res. | pmid:6802634 |
Florén CH and Nilsson A | Effects of hypothyroidism and cholesterol feeding on the clearance of chylomicron remnants in vivo and by rat hepatocyte monolayers. | 1981 | Eur. J. Clin. Invest. | pmid:6783423 |
Feingold KR et al. | Mevalonate metabolism in pregnant rats. | 1980 | Metab. Clin. Exp. | pmid:6774201 |
Habenicht AJ et al. | Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor. | 1980 | J. Biol. Chem. | pmid:6768732 |
Panini SR et al. | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by oxysterol by-products of cholesterol biosynthesis. Possible mediators of low density lipoprotein action. | 1984 | J. Biol. Chem. | pmid:6736025 |
Javitt NB et al. | Rapid synthesis of 26-hydroxycholesterol from mevalonic acid in the Syrian hamster. | 1984 | Biochim. Biophys. Acta | pmid:6733127 |
Kopito RR et al. | The shunt pathway of mevalonate metabolism in the isolated perfused rat kidney. | 1984 | J. Biol. Chem. | pmid:6706942 |
Mills JT and Adamany AM | Impairment of dolichyl saccharide synthesis and dolichol-mediated glycoprotein assembly in the aortic smooth muscle cell in culture by inhibitors of cholesterol biosynthesis. | 1978 | J. Biol. Chem. | pmid:670194 |
Amdur BH et al. | Presence of squalene in gram-positive bacteria. | 1978 | J. Bacteriol. | pmid:670148 |
Heacock AM et al. | Cholesterol synthesis and nerve regeneration. | 1984 | J. Neurochem. | pmid:6699648 |
Fairbanks KP et al. | Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor. | 1984 | J. Biol. Chem. | pmid:6693424 |
Takii Y et al. | Arrest of 3T3 cells in G1 phase by low density lipoprotein. | 1983 | Cell Struct. Funct. | pmid:6671216 |
Dull BJ et al. | The modulating effect of an inhibitor of cholesterolgenesis present in bovine milk upon the synthesis of cholesterol, dolichol and ubiquinone. | 1983 | Atherosclerosis | pmid:6661267 |
Fliesler SJ and Schroepfer GJ | Metabolism of mevalonic acid in cell-free homogenates of bovine retinas. Formation of novel isoprenoid acids. | 1983 | J. Biol. Chem. | pmid:6654904 |
Gavigan SJ and Knight BL | The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. | 1983 | Biochem. J. | pmid:6651782 |
pmid:6642065 | ||||
Goodwin TW | Developments in carotenoid biochemistry over 40 years. The third Morton lecture. | 1983 | Biochem. Soc. Trans. | pmid:6642057 |
Larson RA et al. | Neutrophil-assisted DNA synthesis by human lymphocytes in response to mevalonic acid; enhancement by cytochalasin B. | 1983 | Cell. Immunol. | pmid:6640672 |
Field FJ and Mathur SN | Regulation of acyl CoA:cholesterol acyltransferase by 25-hydroxycholesterol in rabbit intestinal microsomes and absorptive cells. | 1983 | J. Lipid Res. | pmid:6631233 |
Colannino NM and Lipke H | Increased deposition of cholesterol in brain after electroconvulsive seizure. | 1983 | Epilepsia | pmid:6617590 |
Larson RA and Yachnin S | Mevalonic acid induces DNA synthesis in chronic lymphocytic leukemia cells. | 1984 | Blood | pmid:6610447 |
Goodwin CD and Margolis S | Improved methods for the study of hepatic HMG CoA reductase: one-step isolation of mevalonolactone and rapid preparation of endoplasmic reticulum. | 1976 | J. Lipid Res. | pmid:6605 |
Yachnin S et al. | Increased cholesterol biosynthesis in leukemic cells from patients with hairy cell leukemia. | 1983 | Blood | pmid:6600213 |
Beg ZH et al. | In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6594693 |
Maxwell RE et al. | Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats. | 1983 | Atherosclerosis | pmid:6579963 |
Jeng I et al. | Insensitivity of ubiquinone biosynthesis in glioblastoma cells to an epileptogenic drug, U18666A. | 1984 | J. Neurochem. | pmid:6567656 |
Herold G et al. | Cholesterol synthesis and esterification in cultured intestinal mucosa. Evidence for compartmentation. | 1984 | Biochim. Biophys. Acta | pmid:6567470 |
Parker TS et al. | Plasma mevalonate as a measure of cholesterol synthesis in man. | 1984 | J. Clin. Invest. | pmid:6565710 |
Schmidt RA et al. | Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins. | 1984 | J. Biol. Chem. | pmid:6565705 |
Krieger M | The use of amphotericin B to detect inhibitors of cellular cholesterol biosynthesis. | 1983 | Anal. Biochem. | pmid:6559041 |
Davis RA et al. | Bile acid synthesis by cultured hepatocytes. Inhibition by mevinolin, but not by bile acids. | 1983 | J. Biol. Chem. | pmid:6550600 |
Clarke CF et al. | Diurnal rhythm of rat liver mRNAs encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase. Correlation of functional and total mRNA levels with enzyme activity and protein. | 1984 | J. Biol. Chem. | pmid:6540773 |
Aguilera JA et al. | Postnatal development of the sterol and nonsterol mevalonate metabolism in chick liver and kidneys. Effect of cholesterol feeding. | 1984 | Ann. Nutr. Metab. | pmid:6517527 |