Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Luckman SP et al. | Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. | 1998 | J. Bone Miner. Res. | pmid:9556058 |
Kaur M et al. | Receptor-Ck-dependent regulation of genes involved in the cell cycle. | 1998 | Mol. Cell. Biochem. | pmid:9562250 |
Coutant KD et al. | Fluvastatin enhances receptor-stimulated intracellular Ca2+ release in human keratinocytes. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9571146 |
Visioli F et al. | Ethanol enhances cholesterol synthesis and secretion in human hepatomal cells. | 1998 | Alcohol | pmid:9590514 |
Orihara N et al. | Studies on the biosynthesis of terpenoidal compounds produced by actinomycetes. 2. Biosynthesis of carquinostatin B via the non-mevalonate pathway in Streptomyces exfoliatus. | 1997 | J. Antibiot. | pmid:9592576 |
Singh I et al. | Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. | 1998 | FEBS Lett. | pmid:9600263 |
Rubins JB et al. | Lovastatin induces apoptosis in malignant mesothelioma cells. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9603146 |
Crick DC et al. | Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. | 1998 | J. Neurochem. | pmid:9603204 |
Melnykovych G et al. | Inhibition of cholesterol biosynthesis in HeLa cells by glucocorticoids. | 1976 | Biochem. Biophys. Res. Commun. | pmid:962938 |
Mitropoulos KA and Gibbons GF | Effect of triarimol on cholesterol biosynthesis in rat-liver subcellular. | 1976 | Biochem. Biophys. Res. Commun. | pmid:962959 |
Aspbury RA et al. | Isoprenylation of polypeptides in the nematode Caenorhabditis elegans. | 1998 | Biochim. Biophys. Acta | pmid:9630668 |
Adam KP et al. | Involvement of the mevalonic acid pathway and the glyceraldehyde-pyruvate pathway in terpenoid biosynthesis of the liverworts Ricciocarpos natans and Conocephalum conicum. | 1998 | Arch. Biochem. Biophys. | pmid:9633614 |
Ramaswamy NK et al. | A novel pathway for the synthesis of solanidine in the isolated chloroplast from greening potatoes. | 1976 | Eur. J. Biochem. | pmid:964241 |
Vaidya S et al. | Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A. | 1998 | Arch. Biochem. Biophys. | pmid:9647670 |
Nishio E et al. | Alpha1-adrenoreceptor stimulation causes vascular smooth muscle cell hypertrophy: a possible role for isoprenoid intermediates. | 1998 | Eur. J. Pharmacol. | pmid:9650858 |
Disch A et al. | Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. | 1998 | Biochem. J. | pmid:9657979 |
Rieder C et al. | Biosynthesis of the diterpene verrucosan-2beta-ol in the phototrophic eubacterium Chloroflexus aurantiacus. A retrobiosynthetic NMR study. | 1998 | J. Biol. Chem. | pmid:9660767 |
Kashiwagi Y et al. | Mechanical stretch activates a pathway linked to mevalonate metabolism in cultured neonatal rat heart cells. | 1998 | Hypertens. Res. | pmid:9661807 |
Yan D et al. | Biochemical characterization and subcellular localization of the mouse retinitis pigmentosa GTPase regulator (mRpgr). | 1998 | J. Biol. Chem. | pmid:9677393 |
Kitahara M et al. | NK-104, a newly developed HMG-CoA reductase inhibitor, suppresses neointimal thickening by inhibiting smooth muscle cell growth and fibronectin production in balloon-injured rabbit carotid artery. | 1998 | Jpn. J. Pharmacol. | pmid:9681568 |
Pfohl M et al. | Use of cholesterol precursors to assess changes in cholesterol synthesis under non-steady-state conditions. | 1998 | Eur. J. Clin. Invest. | pmid:9693942 |
pmid:9703948 | ||||
Takahashi S et al. | A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9707569 |
Hinson DD et al. | Hematological abnormalities and cholestatic liver disease in two patients with mevalonate kinase deficiency. | 1998 | Am. J. Med. Genet. | pmid:9714005 |
Laufs U and Liao JK | Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. | 1998 | J. Biol. Chem. | pmid:9727051 |
Orihara N et al. | Studies on the biosynthesis of terpenoid compounds produced by actinomycetes. 3. Biosynthesis of the isoprenoid side chain of novobiocin via the non-mevalonate pathway in Streptomyces niveus. | 1998 | J. Antibiot. | pmid:9727394 |
Guijarro C et al. | 3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture. | 1998 | Circ. Res. | pmid:9734471 |
Harrison LE et al. | Phenylacetate inhibits isoprenoid biosynthesis and suppresses growth of human pancreatic carcinoma. | 1998 | Surgery | pmid:9736908 |
Takeuchi N et al. | Feed-back control of cholesterol synthesis in partially hepatectomized rats. | 1976 | Biochim. Biophys. Acta | pmid:974156 |
Aboushadi N and Krisans SK | Analysis of isoprenoid biosynthesis in peroxisomal-deficient Pex2 CHO cell lines. | 1998 | J. Lipid Res. | pmid:9741690 |
Hiramatsu M et al. | Enzyme immunoassay of urinary mevalonic acid and its clinical application. | 1998 | Clin. Chem. | pmid:9761249 |
Coxon FP et al. | Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs. | 1998 | Mol. Pharmacol. | pmid:9765505 |
Ogura M et al. | Further studies on the possible compartmentation of the precursor pool of cholesterol for the biosynthesis of cholic acid in the rat. | 1976 | J. Biochem. | pmid:977552 |
Michikawa M and Yanagisawa K | Apolipoprotein E4 induces neuronal cell death under conditions of suppressed de novo cholesterol synthesis. | 1998 | J. Neurosci. Res. | pmid:9778150 |
Naoumova RP et al. | Cholesterol synthesis is increased in mixed hyperlipidaemia. | 1998 | Biochim. Biophys. Acta | pmid:9795192 |
Schedin S et al. | Alterations in the biosynthesis of cholesterol, dolichol and dolichyl-P in the genetic cholesterol homeostasis disorder, Niemann-Pick type C disease. | 1998 | Biochim. Biophys. Acta | pmid:9795206 |
Lamb DC et al. | A sterol biosynthetic pathway in Mycobacterium. | 1998 | FEBS Lett. | pmid:9804188 |
Disch A and Rohmer M | On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts. | 1998 | FEMS Microbiol. Lett. | pmid:9835029 |
Shipman CM et al. | The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway. | 1998 | Cancer Res. | pmid:9850051 |
Wellburn AR and Hampp R | Uptake of mevalonate and acetate during plastid development. | 1976 | Biochem. J. | pmid:985424 |
Melichar B et al. | Growth inhibitory effects of aromatic fatty acids on ovarian tumor cell lines. | 1998 | Clin. Cancer Res. | pmid:9865922 |
Holleran AL et al. | Effect of tamoxifen on cholesterol synthesis in HepG2 cells and cultured rat hepatocytes. | 1998 | Metab. Clin. Exp. | pmid:9867082 |
Petras SF et al. | HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells. | 1999 | J. Lipid Res. | pmid:9869647 |
pmid:9872842 | ||||
Fisher JE et al. | Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874784 |
pmid:9882513 | ||||
pmid:990276 | ||||
pmid:9920100 | ||||
Nishimura M et al. | Collagen secretion and growth of mesangial cells require geranylgeranylpyrophosphate. | 1999 | Kidney Int. | pmid:9987076 |