Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Xanthomatosis D014973 17 associated lipids
Thrombosis D013927 49 associated lipids
Refsum Disease D012035 19 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Peutz-Jeghers Syndrome D010580 2 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Leukemia D007938 74 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypertension D006973 115 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Glioma D005910 112 associated lipids
Glioblastoma D005909 27 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Celiac Disease D002446 16 associated lipids
Body Weight D001835 333 associated lipids
Biliary Fistula D001658 13 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

Download all related citations
Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Kekki M et al. Measurement of cholesterol synthesis in kinetically defined pools using fecal steroid analysis and double labeling technique in man. 1977 J. Lipid Res. pmid:833511
Langdon R et al. Induction of HMG CoA reductase by the administration of 20,25-diazacholesterol. 1977 J. Lipid Res. pmid:833506
Wiley MH et al. The quantitative role of the kidneys in the in vivo metabolism of mevalonate. 1977 J. Biol. Chem. pmid:833143
Kandutsch AA and Chen HW Consequences of blocked sterol synthesis in cultured cells. DNA synthesis and membrane composition. 1977 J. Biol. Chem. pmid:833134
Preisig-Müller R et al. Heat shock enhances the amount of prenylated Dnaj protein at membranes of glyoxysomes. 1994 Eur. J. Biochem. pmid:8307022
De Cuyper I et al. Determination of changes in serum lathosterol during treatment with simvastatin to evaluate the role of lathosterol as a parameter for whole body cholesterol synthesis. 1993 Clin. Chim. Acta pmid:8306452
pmid:8300194
Schulz S et al. Prenylated proteins and lymphocyte proliferation: inhibition by d-limonene related monoterpenes. 1994 Eur. J. Immunol. pmid:8299679
McCaskill D and Croteau R Procedures for the isolation and quantification of the intermediates of the mevalonic acid pathway. 1993 Anal. Biochem. pmid:8297005
Ng LL et al. 3-Hydroxy-3-methyl glutaryl coenzyme A reductase inhibition modulates vasopressin-stimulated Ca2+ responses in rat A10 vascular smooth muscle cells. 1994 Circ. Res. pmid:8293556
Florin-Christensen M et al. Occurrence of specific sterols in Pneumocystis carinii. 1994 Biochem. Biophys. Res. Commun. pmid:8292026
Betteridge DJ et al. Compactin inhibits cholesterol synthesis in lymphocytes and intestinal mucosa from patients with familial hypercholesterolaemia. 1978 Dec 23-30 Lancet pmid:82843
Firmbach-Kraft I and Stick R The role of CaaX-dependent modifications in membrane association of Xenopus nuclear lamin B3 during meiosis and the fate of B3 in transfected mitotic cells. 1993 J. Cell Biol. pmid:8276888
Correll CC and Edwards PA Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro. 1994 J. Biol. Chem. pmid:8276863
Roullet JB et al. Mevalonate availability and cardiovascular functions. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8265617
Foster JM et al. Biosynthesis of isoprenoid compounds in Schistosoma mansoni. 1993 Mol. Biochem. Parasitol. pmid:8264731
pmid:8261631
Rohmer M et al. Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. 1993 Biochem. J. pmid:8240251
pmid:8236454
pmid:8233712
Derksen A et al. Non-human primate platelets and arterial tissue cannot convert preformed [14C]lanosterol into[14C]cholesterol in vivo. 1976 Biochem. J. pmid:822845
Hoang VQ et al. The regulation of bile acid synthesis in cultured hamster hepatocytes. 1993 Biochem. Soc. Trans. pmid:8224434
Corsini A et al. Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. 1993 Atherosclerosis pmid:8216498
Metz SA et al. Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins. 1993 Biochem. J. pmid:8216234
pmid:8203881
Grünler J et al. Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins. 1994 Biochim. Biophys. Acta pmid:8199197
Kawata S et al. Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2). 1994 Br. J. Cancer pmid:8198962
Terkeltaub R et al. Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells. 1994 J. Leukoc. Biol. pmid:8195701
Aberg F et al. Effects of clofibrate, phthalates and probucol on ubiquinone levels. 1994 Chem. Biol. Interact. pmid:8194121
Carlberg M et al. Mevalonate is essential for growth activation of human fibroblasts: evidence for a critical role of protein glycosylation in the prereplicative period. 1994 Exp. Cell Res. pmid:8187830
Hungund BL et al. In vivo incorporation of [2-14C]mevalonic acid into rat brain complex glycolipids: characterization of glycosylsterols in mammalian brain. 1994 Chem. Phys. Lipids pmid:8181105
pmid:8179595
Sinensky M et al. The processing pathway of prelamin A. 1994 J. Cell. Sci. pmid:8175923
pmid:8169651
Wilde J and Eggerer H Substrate and inhibitor specificity of mevalonate kinase determined with substrate analogues. 1994 Eur. J. Biochem. pmid:8168534
Kelleher JK et al. Isotopomer spectral analysis of cholesterol synthesis: applications in human hepatoma cells. 1994 Am. J. Physiol. pmid:8166258
Hampton RY and Rine J Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast. 1994 J. Cell Biol. pmid:8163547
Ren Z and Gould MN Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol. 1994 Cancer Lett. pmid:8149348
pmid:8147861
Bernini F et al. Requirement for mevalonate in acetylated LDL induction of cholesterol esterification in macrophages. 1993 Atherosclerosis pmid:8141843
pmid:8133281
pmid:8124722
Mellon SH and Deschepper CF Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain. 1993 Brain Res. pmid:8111631
Rahmatullah M and Robishaw JD Direct interaction of the alpha and gamma subunits of the G proteins. Purification and analysis by limited proteolysis. 1994 J. Biol. Chem. pmid:8106401
Capuzzi DM et al. Rapid modulation of lipogenesis by clofibrate in rat and monkey hepatocytes. 1975 Biochim. Biophys. Acta pmid:810176
Giron MD et al. Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1993 Arch. Biochem. Biophys. pmid:8097083
Sagami H et al. Novel isoprenoid modified proteins in Halobacteria. 1994 Biochem. Biophys. Res. Commun. pmid:8093082
Müller-Wieland D et al. Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes. 1994 Biochem. Biophys. Res. Commun. pmid:8074686
pmid:8074684
pmid:807214