Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Liu JC et al. | The in vitro inhibitory effects of crude extracts of traditional Chinese herbs on 3-hydroxy-3-methylglutaryl-coenzyme A reductase on Vero cells. | 2002 | Am. J. Chin. Med. | pmid:12568290 |
pmid:12605351 | ||||
Masamura K et al. | Pitavastatin-induced thrombomodulin expression by endothelial cells acts via inhibition of small G proteins of the Rho family. | 2003 | Arterioscler. Thromb. Vasc. Biol. | pmid:12615662 |
De-Eknamkul W and Potduang B | Biosynthesis of beta-sitosterol and stigmasterol in Croton sublyratus proceeds via a mixed origin of isoprene units. | 2003 | Phytochemistry | pmid:12620352 |
Righetti M et al. | The in vitro metabolism of mevalonate by sterol and non-sterol pathways. | 1976 | J. Biol. Chem. | pmid:1262340 |
Aktas O et al. | Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin. | 2003 | J. Exp. Med. | pmid:12629065 |
Laufs U | Beyond lipid-lowering: effects of statins on endothelial nitric oxide. | 2003 | Eur. J. Clin. Pharmacol. | pmid:12634978 |
pmid:12636409 | ||||
Poirier J | Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. | 2003 | Trends Mol Med | pmid:12657430 |
Abernethy D et al. | In vitro inhibition of rat liver cholest-5en-3 beta-ol (cholesterol) biosynthesis by non-mercurial sulfhydryl reagents. | 1976 | Steroids | pmid:1265795 |
Itoh D et al. | Biosynthesis of chloroplastidic and extrachloroplastidic terpenoids in liverwort cultured cells: 13C serine as a probe of terpene biosynthesis via mevalonate and non-mevalonate pathways. | 2003 | J. Nat. Prod. | pmid:12662088 |
Luan Z et al. | Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages. | 2003 | Arterioscler. Thromb. Vasc. Biol. | pmid:12663370 |
Awad AB et al. | Effect of phytosterols on cholesterol metabolism and MAP kinase in MDA-MB-231 human breast cancer cells. | 2003 | J. Nutr. Biochem. | pmid:12667603 |
Holstein SA and Hohl RJ | Monoterpene regulation of Ras and Ras-related protein expression. | 2003 | J. Lipid Res. | pmid:12671036 |
pmid:12677167 | ||||
pmid:12677170 | ||||
Suzuki K | Effects of S-8527 (1,1-bis(4'-(1'-carboxy-1'-methylpropoxy)phenyl) cyclohexane), a new hypolipidemic compound, on cholesterol and lipoprotein metabolism in rats. | 1976 | Biochem. Pharmacol. | pmid:1267828 |
pmid:12693933 | ||||
Grabińska K and Palamarczyk G | Dolichol biosynthesis in the yeast Saccharomyces cerevisiae: an insight into the regulatory role of farnesyl diphosphate synthase. | 2002 | FEMS Yeast Res. | pmid:12702274 |
Hemmerlin A et al. | Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells. | 2003 | J. Biol. Chem. | pmid:12736259 |
Iguchi T et al. | Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway. | 2003 | Cell. Signal. | pmid:12742232 |
Haslinger B et al. | Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells. | 2003 | Kidney Int. | pmid:12753293 |
pmid:12773152 | ||||
pmid:12778056 | ||||
Hong SB et al. | Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots. | 2003 May-Jun | Biotechnol. Prog. | pmid:12790690 |
pmid:12792788 | ||||
pmid:12796698 | ||||
pmid:12798327 | ||||
Silber JR et al. | The effect of mevalonic acid deprivation on enzymes of DNA replication in cells emerging from quiescence. | 1992 | Biochem. J. | pmid:1281982 |
Hall FC | Put your heart into the joint benefits of statins! | 2003 | Arthritis Res. Ther. | pmid:12823851 |
Zheng YH et al. | Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12824470 |
Houten SM et al. | Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation. | 2003 | Cell. Mol. Life Sci. | pmid:12861380 |
Vamvakopoulos JE and Green C | HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection. | 2003 | BMC Cardiovasc Disord | pmid:12871602 |
pmid:12872277 | ||||
Töyräs A et al. | Inhibition of mevalonate pathway is involved in alendronate-induced cell growth inhibition, but not in cytokine secretion from macrophages in vitro. | 2003 | Eur J Pharm Sci | pmid:12885386 |
Laufs U and Liao JK | Isoprenoid metabolism and the pleiotropic effects of statins. | 2003 | Curr Atheroscler Rep | pmid:12911847 |
Bank I et al. | Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen. | 2003 | Cell. Immunol. | pmid:12914756 |
pmid:12914758 | ||||
Ohashi K et al. | Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene. | 2003 | J. Biol. Chem. | pmid:12920113 |
Meyers CD et al. | Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL. | 2003 | J. Lipid Res. | pmid:12923222 |
Monick MM et al. | Inhibition of Rho family GTPases results in increased TNF-alpha production after lipopolysaccharide exposure. | 2003 | J. Immunol. | pmid:12928415 |
pmid:12941308 | ||||
Blanco-Colio LM et al. | 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors decrease Fas ligand expression and cytotoxicity in activated human T lymphocytes. | 2003 | Circulation | pmid:12952848 |
pmid:12953163 | ||||
Giricz Z et al. | Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis. | 2003 | Basic Res. Cardiol. | pmid:12955403 |
pmid:12957384 | ||||
Shi J et al. | Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation. | 2003 | Blood Coagul. Fibrinolysis | pmid:12960612 |
pmid:12963986 | ||||
Shiota Y et al. | Effects of peroxisome proliferators gemfibrozil and clofibrate on syntheses of dolichol and cholesterol in rat liver. | 2003 | J. Biochem. | pmid:12966067 |
pmid:12969437 |