Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Laufs U et al. | Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. | 1998 | Circulation | pmid:9537338 |
Disch A et al. | Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. | 1998 | Biochem. J. | pmid:9531505 |
Kalra VK and Blankenhorn DH | Abnormal activation of sterol synthesis in lymphocytes of atherosclerotic-susceptible pigeons and heterozygous familial hypercholesterolemic patients. | 1976 | Biochim. Biophys. Acta | pmid:952994 |
Rosenthal RS and Rodwell VW | Purification and characterization of the heteromeric transcriptional activator MvaT of the Pseudomonas mevalonii mvaAB operon. | 1998 | Protein Sci. | pmid:9514272 |
Sul D and Kaneshiro ES | Ubiquinone synthesis by Pneumocystis carinii: incorporation of radiolabeled polyprenyl chain and benzoquinone ring precursors. | 1997 Nov-Dec | J. Eukaryot. Microbiol. | pmid:9508445 |
Ellsworth JL and Starr JR | Inhibition of acyl coenzyme A:cholesterol acyltransferase blocks esterification but not uptake of cholesterol in Caco-2 cells. | 1998 | Metab. Clin. Exp. | pmid:9500571 |
Lange BM et al. | A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9482845 |
Natarajan R et al. | Molecular cloning of the promoter for rat hepatic neutral cholesterol ester hydrolase: evidence for transcriptional regulation by sterols. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9480812 |
Shamburek RD et al. | Intracellular trafficking of the free cholesterol derived from LDL cholesteryl ester is defective in vivo in Niemann-Pick C disease: insights on normal metabolism of HDL and LDL gained from the NP-C mutation. | 1997 | J. Lipid Res. | pmid:9458266 |
Kanayama N et al. | Genetic evaluation of physiological functions of thiolase isoenzymes in the n-alkalane-assimilating yeast Candida tropicalis. | 1998 | J. Bacteriol. | pmid:9457876 |
Kwiterovich PO and Motevalli M | Differential effect of genistein on the stimulation of cholesterol production by basic protein II in normal and hyperapoB fibroblasts. | 1998 | Arterioscler. Thromb. Vasc. Biol. | pmid:9445257 |
Lala A et al. | Apolipoprotein E genotype and cholesterogenesis in polygenic hypercholesterolemia. | 1998 | Metab. Clin. Exp. | pmid:9440485 |
Hrboticky N et al. | Increased cellular triglyceride levels in human monocytic and rat smooth muscle cells after lovastatin. | 1997 | Biochim. Biophys. Acta | pmid:9434135 |
Pfohl M et al. | Upregulation of cholesterol synthesis after acute reduction of low density lipoprotein by apheresis in normocholesterolaemic subjects: evidence for a threshold effect. | 1997 | Atherosclerosis | pmid:9430376 |
pmid:9430371 | ||||
Bianchi C et al. | Influence of breast- and formula-feeding on plasma cholesterol precursor sterols throughout the first year of life. | 1997 | J. Pediatr. | pmid:9427904 |
Tatsuno I et al. | Geranylgeranylpyrophosphate, a metabolite of mevalonate, regulates the cell cycle progression and DNA synthesis in human lymphocytes. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9425279 |
pmid:942445 | ||||
Goto D et al. | Upregulation of low density lipoprotein receptor by gemfibrozil, a hypolipidemic agent, in human hepatoma cells through stabilization of mRNA transcripts. | 1997 | Arterioscler. Thromb. Vasc. Biol. | pmid:9409246 |
Gadbut AP et al. | Induction of the cholesterol metabolic pathway regulates the farnesylation of RAS in embryonic chick heart cells: a new role for ras in regulating the expression of muscarinic receptors and G proteins. | 1997 | EMBO J. | pmid:9405354 |
Dunzendorfer S et al. | Mevalonate-dependent inhibition of transendothelial migration and chemotaxis of human peripheral blood neutrophils by pravastatin. | 1997 | Circ. Res. | pmid:9400376 |
Ukai M et al. | Cholesterol synthesis in germfree and conventional rats. | 1976 | J. Nutr. | pmid:939998 |
Riches FM et al. | Direct association between the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 and plasma mevalonic acid and lathosterol concentrations in man. | 1997 | Atherosclerosis | pmid:9395276 |
Hinson DD et al. | Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways. | 1997 | J. Lipid Res. | pmid:9392419 |
Pahan K et al. | Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. | 1997 | J. Clin. Invest. | pmid:9389730 |
pmid:9389491 | ||||
de Chaves EI et al. | Role of lipoproteins in the delivery of lipids to axons during axonal regeneration. | 1997 | J. Biol. Chem. | pmid:9388216 |
Forman BM et al. | The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9380679 |
Marais AD et al. | Decreased production of low density lipoprotein by atorvastatin after apheresis in homozygous familial hypercholesterolemia. | 1997 | J. Lipid Res. | pmid:9374129 |
Hjertman M et al. | Evidence for protein dolichylation. | 1997 | FEBS Lett. | pmid:9373159 |
Hampton RY and Bhakta H | Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9371780 |
Feillet C et al. | Cholesterol biosynthesis in normocholesterolemic patients after cholesterol removal by plasmapheresis. | 1997 | J Clin Apher | pmid:9365862 |
Edmond J et al. | Mevalonate metabolism: role of kidneys. | 1976 | Science | pmid:935865 |
Cornforth JW | Asymmetry and enzyme action. | 1976 | Science | pmid:935862 |
pmid:9344354 | ||||
Hinson DD et al. | Identification of an active site alanine in mevalonate kinase through characterization of a novel mutation in mevalonate kinase deficiency. | 1997 | J. Biol. Chem. | pmid:9334262 |
Andres DA et al. | Expression cloning of a novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. | 1997 | Arch. Biochem. Biophys. | pmid:9328291 |
Potter D and Miziorko HM | Identification of catalytic residues in human mevalonate kinase. | 1997 | J. Biol. Chem. | pmid:9325256 |
Parmryd I et al. | Chloroplastic prenylated proteins. | 1997 | FEBS Lett. | pmid:9323028 |
Schwender J et al. | Incorporation of 1-deoxy-D-xylulose into isoprene and phytol by higher plants and algae. | 1997 | FEBS Lett. | pmid:9305746 |
Ren Z et al. | Inhibition of type I and type II geranylgeranyl-protein transferases by the monoterpene perillyl alcohol in NIH3T3 cells. | 1997 | Biochem. Pharmacol. | pmid:9296357 |
Knöss W et al. | Biosynthesis of the labdane diterpene marrubiin in Marrubium vulgare via a non-mevalonate pathway. | 1997 | Biochem. J. | pmid:9291117 |
El-Sohemy A and Archer MC | Regulation of mevalonate synthesis in rat mammary glands by dietary n-3 and n-6 polyunsaturated fatty acids. | 1997 | Cancer Res. | pmid:9288773 |
Meigs TE and Simoni RD | Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase. | 1997 | Arch. Biochem. Biophys. | pmid:9281305 |
Cuthbert JA and Lipsky PE | Regulation of proliferation and Ras localization in transformed cells by products of mevalonate metabolism. | 1997 | Cancer Res. | pmid:9270019 |
Sakai M et al. | HMG-CoA reductase inhibitors suppress macrophage growth induced by oxidized low density lipoprotein. | 1997 | Atherosclerosis | pmid:9258407 |
Naoumova RP et al. | Prolonged inhibition of cholesterol synthesis explains the efficacy of atorvastatin. | 1997 | J. Lipid Res. | pmid:9254075 |
Risé P et al. | Effects of simvastatin on the metabolism of polyunsaturated fatty acids and on glycerolipid, cholesterol, and de novo lipid synthesis in THP-1 cells. | 1997 | J. Lipid Res. | pmid:9254057 |
Bergès T et al. | The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase is essential for viability, and a single Leu-to-Pro mutation in a conserved sequence leads to thermosensitivity. | 1997 | J. Bacteriol. | pmid:9244250 |
Cenedella RJ | Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols. | 1997 | Exp. Eye Res. | pmid:9237866 |