Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Yano K | Lipid metabolic pathways as lung cancer therapeutic targets: a computational study. | 2012 | Int. J. Mol. Med. | pmid:22211244 |
Mans RA et al. | Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. | 2012 | Neuroscience | pmid:22192838 |
Murphy LA et al. | Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22361350 |
Trapani L et al. | 3-hydroxy 3-methylglutaryl coenzyme A reductase inhibition impairs muscle regeneration. | 2012 | J. Cell. Biochem. | pmid:22274883 |
Henriquez MA et al. | Effects of glucans and eicosapentaenoic acid on differential regulation of phenylpropanoid and mevalonic pathways during potato response to Phytophthora infestans. | 2012 | Plant Physiol. Biochem. | pmid:22922112 |
Song AA et al. | Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production. | 2012 | PLoS ONE | pmid:23300671 |
Partow S et al. | Reconstruction and evaluation of the synthetic bacterial MEP pathway in Saccharomyces cerevisiae. | 2012 | PLoS ONE | pmid:23285068 |
Drabkin HA and Gemmill RM | Cholesterol and the development of clear-cell renal carcinoma. | 2012 | Curr Opin Pharmacol | pmid:22939900 |
Rad SA et al. | Type 2 IDI performs better than type 1 for improving lycopene production in metabolically engineered E. coli strains. | 2012 | World J. Microbiol. Biotechnol. | pmid:22806807 |
Campia I et al. | Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes. | 2012 | Biochem. J. | pmid:22845468 |
Zhang B et al. | Interference in mevalonate pathway ameliorates homocysteine-induced endothelium-dysfunction. | 2012 | Eur. J. Pharmacol. | pmid:22796672 |
Yokota K et al. | Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. | 2011 Jan-Feb | Clin. Exp. Rheumatol. | pmid:21345291 |
Redding-Johanson AM et al. | Targeted proteomics for metabolic pathway optimization: application to terpene production. | 2011 | Metab. Eng. | pmid:21215324 |
Huang SH et al. | Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin. | 2011 | PLoS ONE | pmid:21966365 |
Ramgolam VS and Markovic-Plese S | Regulation of suppressors of cytokine signaling as a therapeutic approach in autoimmune diseases, with an emphasis on multiple sclerosis. | 2011 | J Signal Transduct | pmid:22132325 |
Cho SH et al. | Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller. | 2011 | Nutr Res Pract | pmid:22125678 |
Tijerino A et al. | Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. | 2011 | Toxins (Basel) | pmid:22069764 |
Wang H et al. | Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. | 2011 | J. Immunol. | pmid:22013129 |
Ali OF et al. | Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. | 2011 | Respir. Res. | pmid:21999923 |
Waldron J and Webster C | Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. | 2011 | Ann. Clin. Biochem. | pmid:21355014 |
Rossoni LV et al. | Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries. | 2011 | Clin. Sci. | pmid:21671887 |
Maekawa T et al. | Chronic oral infection with Porphyromonas gingivalis accelerates atheroma formation by shifting the lipid profile. | 2011 | PLoS ONE | pmid:21625524 |
Jeon JG et al. | Natural products in caries research: current (limited) knowledge, challenges and future perspective. | 2011 | Caries Res. | pmid:21576957 |
Scheller EL et al. | Bisphosphonates inhibit expression of p63 by oral keratinocytes. | 2011 | J. Dent. Res. | pmid:21551338 |
Kishi T | Mevalonate pathway is a novel target for hypertension. | 2011 | Circ. J. | pmid:21532185 |
Sakamoto K et al. | Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes. | 2011 | BMC Musculoskelet Disord | pmid:21524281 |
Brock NL et al. | Biosynthesis of sesqui- and diterpenes by the gibberellin producer Fusarium fujikuroi. | 2011 | Chembiochem | pmid:21990128 |
Soliman SS et al. | Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways. | 2011 | J. Nat. Prod. | pmid:22103292 |
Henneman L et al. | Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS. | 2011 | Biochim. Biophys. Acta | pmid:21237288 |
Tsubaki M et al. | Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma. | 2011 | Cytokine | pmid:21292498 |
Cluis CP et al. | Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). | 2011 | Metab. Eng. | pmid:21986057 |
Kim KH et al. | Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants. | 2011 | Drug Metab. Dispos. | pmid:20962060 |
Miziorko HM | Enzymes of the mevalonate pathway of isoprenoid biosynthesis. | 2011 | Arch. Biochem. Biophys. | pmid:20932952 |
Tsuyuki R et al. | Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride. | 2011 | J. Agric. Food Chem. | pmid:21299216 |
Kimachi K et al. | Zoledronic acid inhibits RANK expression and migration of osteoclast precursors during osteoclastogenesis. | 2011 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:21225243 |
Epplen R et al. | Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. | 2011 | Acta Oncol | pmid:20429730 |
Lin Y et al. | Triterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters. | 2011 | Evid Based Complement Alternat Med | pmid:19228775 |
Murtola TJ et al. | Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL. | 2011 | Eur. J. Pharmacol. | pmid:22040920 |
Sakai H and Heike T | [Hyperimmunoglobulinemia D and periodic fever syndrome]. | 2011 | Nihon Rinsho Meneki Gakkai Kaishi | pmid:22041426 |
Goto T et al. | Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. | 2011 | Biochem. J. | pmid:21605082 |
Clastre M et al. | Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. | 2011 | Plant Signal Behav | pmid:22080790 |
Soto G et al. | Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation. | 2011 | J. Exp. Bot. | pmid:21908473 |
Wong DH et al. | Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells. | 2011 | Fertil. Steril. | pmid:21907337 |
Kim YS et al. | Increase of lycopene production by supplementing auxiliary carbon sources in metabolically engineered Escherichia coli. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21246354 |
Duke SO and Dayan FE | Modes of action of microbially-produced phytotoxins. | 2011 | Toxins (Basel) | pmid:22069756 |
Banfi C et al. | Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro. | 2011 | J. Thromb. Haemost. | pmid:21605334 |
Martinez-Moya P et al. | Proteomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous. | 2011 | BMC Microbiol. | pmid:21669001 |
Musso A et al. | Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival. | 2011 | Haematologica | pmid:20884711 |
Barta ML et al. | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. | 2011 | J. Biol. Chem. | pmid:21561869 |
Vallianou I et al. | Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. | 2011 | PLoS ONE | pmid:22073134 |