| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioblastoma | D005909 | 27 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ginestier C et al. | Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target. | 2012 | Stem Cells | pmid:22605458 |
| Haratake A et al. | Acceleration of de novo cholesterol synthesis in the epidermis influences desquamation of the stratum corneum in aged mice. | 2006 | Skin Pharmacol Physiol | pmid:16778459 |
| Kodaman PH and Duleba AJ | Statins in the treatment of polycystic ovary syndrome. | 2008 | Semin. Reprod. Med. | pmid:18181091 |
| Bellosta S et al. | Statins effect on smooth muscle cell proliferation. | 2004 | Semin Vasc Med | pmid:15861311 |
| Cornforth JW | Asymmetry and enzyme action. | 1976 | Science | pmid:935862 |
| Edmond J et al. | Mevalonate metabolism: role of kidneys. | 1976 | Science | pmid:935865 |
| Farnsworth CC et al. | Identification of geranylgeranyl-modified proteins in HeLa cells. | 1990 | Science | pmid:2296721 |
| MEROLA AJ and ARNOLD A | ESTRONE INHIBITION OF CHOLESTEROL BIOSYNTHESIS AT THE MEVALONIC ACID STAGE. | 1964 | Science | pmid:14169718 |
| FIMOGNARI GM and RODWELL VW | CHOLESTEROL BIOSYNTHESIS: MEVALONATE SYNTHESIS INHIBITED BY BILE SALTS. | 1965 | Science | pmid:14245778 |
| Graebe JE | Isoprenoid biosynthesis in a cell-free system from pea shoots. | 1967 | Science | pmid:4381746 |
| Yi P et al. | The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1. | 2006 | Science | pmid:16857902 |
| Galli G et al. | Sterol precursors of cholesterol in adult human brain. | 1968 | Science | pmid:5700071 |
| Jomaa H et al. | Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. | 1999 | Science | pmid:10477522 |
| Matsumoto Y et al. | A critical role of mevalonate for peptidoglycan synthesis in Staphylococcus aureus. | 2016 | Sci Rep | pmid:26961421 |
| Pina ES et al. | Mevalonate-derived quinonemethide triterpenoid from in vitro roots of Peritassa laevigata and their localization in root tissue by MALDI imaging. | 2016 | Sci Rep | pmid:26943243 |
| Kain V et al. | Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism. | 2015 | Sci Rep | pmid:26345110 |
| Warita K et al. | Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. | 2014 | Sci Rep | pmid:25534349 |
| Omar SH | Oleuropein in olive and its pharmacological effects. | 2010 Apr-Jun | Sci Pharm | pmid:21179340 |
| Feitosa AO et al. | Lethality of cytochalasin B and other compounds isolated from fungus Aspergillus sp. (Trichocomaceae) endophyte of Bauhinia guianensis (Fabaceae). | 2016 Jul - Sep | Rev. Argent. Microbiol. | pmid:27567521 |
| Ali OF et al. | Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. | 2011 | Respir. Res. | pmid:21999923 |
| Schaafsma D et al. | Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. | 2011 | Respir. Res. | pmid:21864337 |
| Capra V and Rovati GE | Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents. | 2014 | Pulm Pharmacol Ther | pmid:23806820 |
| Olson AL et al. | Substrate induced structural and dynamics changes in human phosphomevalonate kinase and implications for mechanism. | 2009 | Proteins | pmid:18798562 |
| Vinokur JM et al. | Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. | 2015 | Protein Sci. | pmid:25422158 |
| Korman TP et al. | A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates. | 2014 | Protein Sci. | pmid:24623472 |
| Rosenthal RS and Rodwell VW | Purification and characterization of the heteromeric transcriptional activator MvaT of the Pseudomonas mevalonii mvaAB operon. | 1998 | Protein Sci. | pmid:9514272 |
| Andreassi JL et al. | Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate. | 2007 | Protein Sci. | pmid:17400916 |
| Hedl M and Rodwell VW | Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii. | 2004 | Protein Sci. | pmid:15152097 |
| Hedl M and Rodwell VW | Enterococcus faecalis mevalonate kinase. | 2004 | Protein Sci. | pmid:14767074 |
| Kim DY et al. | Expression and characterization of the HMG-CoA reductase of the thermophilic archaeon Sulfolobus solfataricus. | 1999 | Protein Expr. Purif. | pmid:10600463 |
| Yildirim FI et al. | Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. | 2015 | Prostaglandins Other Lipid Mediat. | pmid:26201058 |
| Kabara JJ | A critical review of brain cholesterol metabolism. | 1973 | Prog. Brain Res. | pmid:4608424 |
| Popják G and Meenan A | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase: search for the enzyme's repressor derived from mevalonate. | 1987 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:2892200 |
| Cornforth J | Symmetry of squalene epoxidation in vivo. | 1977 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:22855 |
| Jakóbisiak M et al. | Cell cycle-specific effects of lovastatin. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1673788 |
| Jackson JH et al. | Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2183224 |
| Saito Y et al. | Animal cell mutants defective in sterol metabolism: a specific selection procedure and partial characterization of defects. | 1977 | Proc. Natl. Acad. Sci. U.S.A. | pmid:269426 |
| Autefage H et al. | Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25831522 |
| Polotskaia A et al. | Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25733866 |
| Fisher JE et al. | Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874784 |
| Sinensky M et al. | Somatic cell genetic analysis of regulation of expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6935672 |
| Xiong M et al. | Scalable production of mechanically tunable block polymers from sugar. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24912182 |
| Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
| Goldstein JL et al. | Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor. | 1975 | Proc. Natl. Acad. Sci. U.S.A. | pmid:236556 |
| Kotti TJ et al. | Brain cholesterol turnover required for geranylgeraniol production and learning in mice. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16505352 |
| Arebalo RE et al. | In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6256737 |
| Dudareva N et al. | The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15630092 |
| Money T et al. | Biosynthesis of the indole alkaloids. | 1965 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5222559 |
| Lange BM et al. | A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9482845 |
| Zheng YH et al. | Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12824470 |