| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioblastoma | D005909 | 27 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wani TA et al. | The effects of rosuvastatin on the serum cortisol, serum lipid, and serum mevalonic acid levels in the healthy Indian male population. | 2010 | AAPS PharmSciTech | pmid:20300897 |
| Björkhem-Bergman L et al. | Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. | 2010 | Anticancer Res. | pmid:20530415 |
| Morrone D et al. | Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19777230 |
| Wang C et al. | Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. | 2010 | Biotechnol. Bioeng. | pmid:20552672 |
| Honour JW | Steroid assays in paediatric endocrinology. | 2010 | J Clin Res Pediatr Endocrinol | pmid:21274330 |
| Head BP et al. | Loss of caveolin-1 accelerates neurodegeneration and aging. | 2010 | PLoS ONE | pmid:21203469 |
| Hamdy RC | Zoledronic acid: clinical utility and patient considerations in osteoporosis and low bone mass. | 2010 | Drug Des Devel Ther | pmid:21151620 |
| Stapleton PA et al. | Hypercholesterolemia and microvascular dysfunction: interventional strategies. | 2010 | J Inflamm (Lond) | pmid:21087503 |
| Hughes M et al. | Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP. | 2010 | J. Neurochem. | pmid:20477946 |
| Targett-Adams P et al. | Lipid metabolism and HCV infection. | 2010 | Viruses | pmid:21994676 |
| Snoeren TA et al. | The herbivore-induced plant volatile methyl salicylate negatively affects attraction of the parasitoid Diadegma semiclausum. | 2010 | J. Chem. Ecol. | pmid:20407809 |
| Lefurgy ST et al. | Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae. | 2010 | J. Biol. Chem. | pmid:20404339 |
| Clendening JW et al. | Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma. | 2010 | Blood | pmid:20360469 |
| Delang L et al. | Antiviral therapy for hepatitis C virus: beyond the standard of care. | 2010 | Viruses | pmid:21994657 |
| Klawitter J et al. | Effects of lovastatin on breast cancer cells: a proteo-metabonomic study. | 2010 | Breast Cancer Res. | pmid:20205716 |
| Catros V et al. | [Tgammadelta lymphocytes in oncology: unconventional killer lymphocytes]. | 2010 | Med Sci (Paris) | pmid:20188051 |
| Pontillo A et al. | The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency. | 2010 | Eur. J. Hum. Genet. | pmid:20179743 |
| Yamauchi N | The pathway of leucine to mevalonate in halophilic archaea: efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20139592 |
| Yang Z et al. | Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. | 2010 | Int. J. Cancer | pmid:19626588 |
| Coscia M et al. | Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. | 2010 | J. Cell. Mol. Med. | pmid:19818098 |
| Kones R | Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. | 2010 | Drug Des Devel Ther | pmid:21267417 |
| Hooff GP et al. | Isoprenoids, small GTPases and Alzheimer's disease. | 2010 | Biochim. Biophys. Acta | pmid:20382260 |
| Räikkönen J et al. | Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. | 2010 | Biochem. Pharmacol. | pmid:19819230 |
| Singh RS et al. | Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston]. | 2010 | BMC Mol. Biol. | pmid:21092138 |
| Tsuchiya M et al. | Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta-cells. | 2010 | Endocrinology | pmid:20685866 |
| Chang TH et al. | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. | 2010 | Plant Cell | pmid:20139160 |
| Quist-Paulsen P | Statins and inflammation: an update. | 2010 | Curr. Opin. Cardiol. | pmid:20421792 |
| Endo A | A historical perspective on the discovery of statins. | 2010 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:20467214 |
| Tekpli X et al. | Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis. | 2010 | Toxicol. Appl. Pharmacol. | pmid:19931295 |
| Chen CC et al. | Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43. | 2010 | J. Appl. Physiol. | pmid:20466804 |
| Norman KL and Sarnow P | Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms. | 2010 | J. Virol. | pmid:19846523 |
| Kato S et al. | Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase. | 2010 | J. Cell. Mol. Med. | pmid:19432822 |
| Hooff GP et al. | Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein production. | 2010 | Mol. Neurobiol. | pmid:20405344 |
| Jiang XS et al. | Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency. | 2010 | Mol. Cell Proteomics | pmid:20305089 |
| Huang M et al. | Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. | 2010 | Plant Physiol. | pmid:20463089 |
| Weerasinghe S and Samantha Dassanayake R | Simulation of structural and functional properties of mevalonate diphosphate decarboxylase (MVD). | 2010 | J Mol Model | pmid:19653015 |
| Omar SH | Oleuropein in olive and its pharmacological effects. | 2010 Apr-Jun | Sci Pharm | pmid:21179340 |
| Camps D | [Controversies regarding the use of statins in the acute coronary syndrome]. | 2010 Aug-Sep | Med Intensiva | pmid:20538377 |
| Maki KC et al. | Effects of soy protein on lipoprotein lipids and fecal bile acid excretion in men and women with moderate hypercholesterolemia. | 2010 Nov-Dec | J Clin Lipidol | pmid:21122701 |
| Huang SH et al. | Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin. | 2011 | PLoS ONE | pmid:21966365 |
| Singh NK et al. | 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. | 2011 | Blood | pmid:21841162 |
| Ma SM et al. | Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases. | 2011 | Metab. Eng. | pmid:21810477 |
| Yu F et al. | Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. | 2011 | Cell. Mol. Life Sci. | pmid:20730551 |
| Luo H et al. | Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. | 2011 | BMC Genomics | pmid:22369100 |
| Youn YN et al. | Impact of High-Dose Statin Pretreatment in Patients with Stable Angina during Off-Pump Coronary Artery Bypass. | 2011 | Korean J Thorac Cardiovasc Surg | pmid:22263153 |
| Nes WD | Biosynthesis of cholesterol and other sterols. | 2011 | Chem. Rev. | pmid:21902244 |
| Tijerino A et al. | Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. | 2011 | Toxins (Basel) | pmid:22069764 |
| Wang H et al. | Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. | 2011 | J. Immunol. | pmid:22013129 |
| Ali OF et al. | Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. | 2011 | Respir. Res. | pmid:21999923 |
| Bergman P et al. | Studies on the antibacterial effects of statins--in vitro and in vivo. | 2011 | PLoS ONE | pmid:21912631 |
| Emma F et al. | Renal mitochondrial cytopathies. | 2011 | Int J Nephrol | pmid:21811680 |
| Ageenko NV et al. | Expression of Pigment Cell-Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius. | 2011 | Evid Based Complement Alternat Med | pmid:21804858 |
| Cheng G et al. | Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. | 2011 | Cancer Biol. Ther. | pmid:21799303 |
| Katuru R et al. | Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21540247 |
| Peng LF et al. | Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. | 2011 | J. Infect. Dis. | pmid:21791663 |
| Bajgain P et al. | Transcriptome characterization and polymorphism detection between subspecies of big sagebrush (Artemisia tridentata). | 2011 | BMC Genomics | pmid:21767398 |
| Waldron J and Webster C | Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. | 2011 | Ann. Clin. Biochem. | pmid:21355014 |
| Maekawa T et al. | Chronic oral infection with Porphyromonas gingivalis accelerates atheroma formation by shifting the lipid profile. | 2011 | PLoS ONE | pmid:21625524 |
| Jeon JG et al. | Natural products in caries research: current (limited) knowledge, challenges and future perspective. | 2011 | Caries Res. | pmid:21576957 |
| Scheller EL et al. | Bisphosphonates inhibit expression of p63 by oral keratinocytes. | 2011 | J. Dent. Res. | pmid:21551338 |
| Kishi T | Mevalonate pathway is a novel target for hypertension. | 2011 | Circ. J. | pmid:21532185 |
| Sakamoto K et al. | Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes. | 2011 | BMC Musculoskelet Disord | pmid:21524281 |
| Han J et al. | Alteration of enzyme expressions in mevalonate pathway: possible role for cardiovascular remodeling in spontaneously hypertensive rats. | 2011 | Circ. J. | pmid:21467659 |
| Song JX et al. | Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21052011 |
| Siddals KW et al. | Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization. | 2011 | J. Biol. Chem. | pmid:21454560 |
| Mongélard G et al. | Measurement of carbon flux through the MEP pathway for isoprenoid synthesis by (31)P-NMR spectroscopy after specific inhibition of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate reductase. Effect of light and temperature. | 2011 | Plant Cell Environ. | pmid:21443577 |
| Zhang B et al. | A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. | 2011 | Biochemistry | pmid:21438569 |
| Kim RH et al. | Bisphosphonates induce senescence in normal human oral keratinocytes. | 2011 | J. Dent. Res. | pmid:21427353 |
| Kyathanahalli CN and Kowluru A | A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGEâ‚‚. | 2011 | Biochem. Pharmacol. | pmid:21406184 |
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| Blankier S et al. | The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease. | 2011 | Clin. Exp. Immunol. | pmid:21361911 |
| Ghavami S et al. | Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. | 2011 | PLoS ONE | pmid:21304979 |
| Ignea C et al. | Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. | 2011 | Microb. Cell Fact. | pmid:21276210 |
| Kim KH et al. | Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants. | 2011 | Drug Metab. Dispos. | pmid:20962060 |
| Miziorko HM | Enzymes of the mevalonate pathway of isoprenoid biosynthesis. | 2011 | Arch. Biochem. Biophys. | pmid:20932952 |
| Tsuyuki R et al. | Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride. | 2011 | J. Agric. Food Chem. | pmid:21299216 |
| Li YY et al. | Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression. | 2011 | Anticancer Drugs | pmid:20926944 |
| Nilsson S et al. | Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells. | 2011 | Cancer Lett. | pmid:21356574 |
| Liu Q et al. | Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. | 2011 | PLoS ONE | pmid:21858047 |
| Jouneau S et al. | Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. | 2011 | PLoS ONE | pmid:21826199 |
| Sakai H and Heike T | [Hyperimmunoglobulinemia D and periodic fever syndrome]. | 2011 | Nihon Rinsho Meneki Gakkai Kaishi | pmid:22041426 |
| Issat T et al. | Antitumor effects of the combination of cholesterol reducing drugs. | 2011 | Oncol. Rep. | pmid:21491092 |
| Zeki AA et al. | Statin drugs, metabolic pathways, and asthma: a therapeutic opportunity needing further research. | 2011 | Drug Metab Lett | pmid:21198438 |
| Llacuna L et al. | Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia-reperfusion injury. | 2011 | J. Hepatol. | pmid:21145825 |
| Hamada M et al. | Antithrombotic properties of pravastatin reducing intra-thrombus fibrin deposition under high shear blood flow conditions. | 2011 | Thromb. Haemost. | pmid:21136018 |
| Goto T et al. | Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. | 2011 | Biochem. J. | pmid:21605082 |
| Hao Q et al. | Synthesis and anti-hypercholesterolemic evaluations of calcium salts of 4-substituted quinoline-based mevalonic acid. | 2011 | Chem Biol Drug Des | pmid:21791012 |
| Clastre M et al. | Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. | 2011 | Plant Signal Behav | pmid:22080790 |
| Duke SO and Dayan FE | Modes of action of microbially-produced phytotoxins. | 2011 | Toxins (Basel) | pmid:22069756 |
| Kindt E et al. | The validation of a simple LC/MS/MS method for determining the level of mevalonic acid in human plasma. | 2011 | Biomed. Chromatogr. | pmid:21110384 |
| Banfi C et al. | Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro. | 2011 | J. Thromb. Haemost. | pmid:21605334 |
| Musso A et al. | Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival. | 2011 | Haematologica | pmid:20884711 |
| Jang HJ et al. | Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. | 2011 | Microb. Cell Fact. | pmid:21801353 |
| Schaafsma D et al. | Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. | 2011 | Respir. Res. | pmid:21864337 |
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| Simkin AJ et al. | Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta. | 2011 | Planta | pmid:21655959 |
| Barta ML et al. | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. | 2011 | J. Biol. Chem. | pmid:21561869 |
| Vallianou I et al. | Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. | 2011 | PLoS ONE | pmid:22073134 |
| Kaneko M et al. | Effect of farnesol on mevalonate pathway of Staphylococcus aureus. | 2011 | J. Antibiot. | pmid:21772307 |
| Yanae M et al. | Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. | 2011 | J. Exp. Clin. Cancer Res. | pmid:21831290 |