Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Glioblastoma D005909 27 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Hypothyroidism D007037 32 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Thrombosis D013927 49 associated lipids
Leukemia D007938 74 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Honda A et al. Effect of YM 9429, a potent teratogen, on cholesterol biosynthesis in cultured cells and rat liver microsomes. 1996 Steroids pmid:8883221
Richardson B et al. Sterol metabolism in normal and tobacco mosaic virus-infected tobacco plants. 1968 Steroids pmid:5642319
Canonica L et al. The biological conversion of 5alpha-cholest-8-en-3beta-ol to 5alpha-cholest-7-en-3beta-ol in the biosynthesis of cholesterol. 1968 Steroids pmid:5642322
Maitra US et al. Biosynthetic preparation of labeled 4,4-dimethylzymosterol. 1989 Mar-May Steroids pmid:2799859
McEvoy D et al. The effect of stress on the biosynthesis of cortisol (11beta, 17alpha, 21-trihydroxy pregn-4-ene-3, 20-sione). 1968 Steroids pmid:5674519
Seo S et al. Effect of sterol biosynthesis inhibitor, SSF-109, on cholesterol synthesis in isolated rat hepatocytes. 1993 Steroids pmid:8484187
Subden RE and Renaud RL Isolation of 4 alpha-methyl-5 alpha-ergosta-8,24(28)-dien-3 beta-ol from ester fractions of nutritionally deprived Neurospora crassa. 1979 Steroids pmid:161433
Haksar A and Romanoff EB On the possible site of pregenolone inyibition of sterol biosynthesis in the bovine corpus luteum (1,2). 1968 Steroids pmid:5674524
Abernethy D et al. In vitro inhibition of rat liver cholest-5en-3 beta-ol (cholesterol) biosynthesis by non-mercurial sulfhydryl reagents. 1976 Steroids pmid:1265795
Ginestier C et al. Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target. 2012 Stem Cells pmid:22605458
Lee MH et al. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation. 2007 Stem Cells pmid:17464088
Haratake A et al. Acceleration of de novo cholesterol synthesis in the epidermis influences desquamation of the stratum corneum in aged mice. 2006 Skin Pharmacol Physiol pmid:16778459
Kodaman PH and Duleba AJ Statins in the treatment of polycystic ovary syndrome. 2008 Semin. Reprod. Med. pmid:18181091
Bellosta S et al. Statins effect on smooth muscle cell proliferation. 2004 Semin Vasc Med pmid:15861311
Cornforth JW Asymmetry and enzyme action. 1976 Science pmid:935862
Edmond J et al. Mevalonate metabolism: role of kidneys. 1976 Science pmid:935865
Farnsworth CC et al. Identification of geranylgeranyl-modified proteins in HeLa cells. 1990 Science pmid:2296721
FIMOGNARI GM and RODWELL VW CHOLESTEROL BIOSYNTHESIS: MEVALONATE SYNTHESIS INHIBITED BY BILE SALTS. 1965 Science pmid:14245778
Yi P et al. The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1. 2006 Science pmid:16857902
Galli G et al. Sterol precursors of cholesterol in adult human brain. 1968 Science pmid:5700071