Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Glioblastoma D005909 27 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Hypothyroidism D007037 32 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Thrombosis D013927 49 associated lipids
Leukemia D007938 74 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
MEROLA AJ and ARNOLD A ESTRONE INHIBITION OF CHOLESTEROL BIOSYNTHESIS AT THE MEVALONIC ACID STAGE. 1964 Science pmid:14169718
Graebe JE Isoprenoid biosynthesis in a cell-free system from pea shoots. 1967 Science pmid:4381746
Jomaa H et al. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. 1999 Science pmid:10477522
Matsumoto Y et al. A critical role of mevalonate for peptidoglycan synthesis in Staphylococcus aureus. 2016 Sci Rep pmid:26961421
Pina ES et al. Mevalonate-derived quinonemethide triterpenoid from in vitro roots of Peritassa laevigata and their localization in root tissue by MALDI imaging. 2016 Sci Rep pmid:26943243
Kain V et al. Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism. 2015 Sci Rep pmid:26345110
Warita K et al. Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. 2014 Sci Rep pmid:25534349
Omar SH Oleuropein in olive and its pharmacological effects. 2010 Apr-Jun Sci Pharm pmid:21179340
Feitosa AO et al. Lethality of cytochalasin B and other compounds isolated from fungus Aspergillus sp. (Trichocomaceae) endophyte of Bauhinia guianensis (Fabaceae). 2016 Jul - Sep Rev. Argent. Microbiol. pmid:27567521
Ali OF et al. Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. 2011 Respir. Res. pmid:21999923
Schaafsma D et al. Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. 2011 Respir. Res. pmid:21864337
Capra V and Rovati GE Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents. 2014 Pulm Pharmacol Ther pmid:23806820
Olson AL et al. Substrate induced structural and dynamics changes in human phosphomevalonate kinase and implications for mechanism. 2009 Proteins pmid:18798562
Vinokur JM et al. Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. 2015 Protein Sci. pmid:25422158
Korman TP et al. A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates. 2014 Protein Sci. pmid:24623472
Rosenthal RS and Rodwell VW Purification and characterization of the heteromeric transcriptional activator MvaT of the Pseudomonas mevalonii mvaAB operon. 1998 Protein Sci. pmid:9514272
Andreassi JL et al. Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate. 2007 Protein Sci. pmid:17400916
Hedl M and Rodwell VW Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii. 2004 Protein Sci. pmid:15152097
Hedl M and Rodwell VW Enterococcus faecalis mevalonate kinase. 2004 Protein Sci. pmid:14767074
Kim DY et al. Expression and characterization of the HMG-CoA reductase of the thermophilic archaeon Sulfolobus solfataricus. 1999 Protein Expr. Purif. pmid:10600463