Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Glioblastoma D005909 27 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Hypothyroidism D007037 32 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Thrombosis D013927 49 associated lipids
Leukemia D007938 74 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

Download all related citations
Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Yildirim FI et al. Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. 2015 Prostaglandins Other Lipid Mediat. pmid:26201058
Kabara JJ A critical review of brain cholesterol metabolism. 1973 Prog. Brain Res. pmid:4608424
Popják G and Meenan A Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase: search for the enzyme's repressor derived from mevalonate. 1987 Proc. R. Soc. Lond., B, Biol. Sci. pmid:2892200
Cornforth J Symmetry of squalene epoxidation in vivo. 1977 Proc. R. Soc. Lond., B, Biol. Sci. pmid:22855
Kotti T et al. Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18685105
Mizuno T et al. A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1907371
Roullet JB et al. Mevalonate availability and cardiovascular functions. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8265617
Sinensky M and Logel J Defective macromolecule biosynthesis and cell-cycle progression in a mammalian cell starved for mevalonate. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:2582409
Goldstein JL and Brown MS Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. 1973 Proc. Natl. Acad. Sci. U.S.A. pmid:4355366
Quesney-Huneeus V et al. Essential role for mevalonate synthesis in DNA replication. 1979 Proc. Natl. Acad. Sci. U.S.A. pmid:291922
Laffitte BA et al. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11149950
Henry LK et al. Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26216978
Venkateshwaran M et al. A role for the mevalonate pathway in early plant symbiotic signaling. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26199419
Parmryd I et al. Protein prenylation in spinach chloroplasts. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10468564
Lai RK et al. The gamma subunit of transducin is farnesylated. 1990 Proc. Natl. Acad. Sci. U.S.A. pmid:2217200
Sapir A et al. Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25187565
Farnsworth CC et al. C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1906176
Ness GC et al. Stimulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in hypophysectomized rats by L-triiodothyronine. 1973 Proc. Natl. Acad. Sci. U.S.A. pmid:4521209
Okamura E et al. Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20534558
Ohyama K et al. Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19139393