| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioblastoma | D005909 | 27 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Asada Y et al. | Biosynthesis of the dimethylallyl moiety of glabrol in Glycyrrhiza glabra hairy root cultures via a non-mevalonate pathway. | 2000 | Phytochemistry | pmid:11117880 |
| Kutrzeba L et al. | Biosynthesis of salvinorin A proceeds via the deoxyxylulose phosphate pathway. | 2007 | Phytochemistry | pmid:17574635 |
| Thiel R and Adam KP | Incorporation of [1-(13)C]1-deoxy-D-xylulose into isoprenoids of the liverwort Conocephalum conicum. | 2002 | Phytochemistry | pmid:11830134 |
| Han YS et al. | Biosynthesis of anthraquinones in cell cultures of Cinchona 'Robusta' proceeds via the methylerythritol 4-phosphate pathway. | 2002 | Phytochemistry | pmid:11754943 |
| Khandelwal VK et al. | Oxidative stress plays an important role in zoledronic acid-induced autophagy. | 2014 | Physiol Res | pmid:25669691 |
| Ohm TG et al. | Cholesterol and tau protein--findings in Alzheimer's and Niemann Pick C's disease. | 2003 | Pharmacopsychiatry | pmid:14574625 |
| Chang JJ et al. | The in vitro inhibitory effect of tannin derivatives on 3-hydroxy-3-methylglutaryl-coenzyme a reductase on vero cells. | 2001 | Pharmacology | pmid:11359999 |
| Khan SA and Nyce JW | Effects of ubiquinone and mevalonic acid on hepatic peroxisomal enzymes induced by dehydroepiandrosterone. | 1997 | Pharmacol. Toxicol. | pmid:9101583 |
| Yeganeh B et al. | Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. | 2014 | Pharmacol. Ther. | pmid:24582968 |
| De Leo L et al. | Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches. | 2010 | Pharmacol. Res. | pmid:20206266 |
| Corsini A et al. | Pharmacology of competitive inhibitors of HMG-CoA reductase. | 1995 | Pharmacol. Res. | pmid:7784310 |
| Jana S and Shekhawat GS | Anethum graveolens: An Indian traditional medicinal herb and spice. | 2010 | Pharmacogn Rev | pmid:22228959 |
| Vishnuvardhan D and Beinfeld MC | Lovastatin is a potent inhibitor of cholecystokinin secretion in endocrine tumor cells in culture. | 2000 | Peptides | pmid:10822111 |
| Kyriakides EC et al. | Lipid studies in Wolman's disease. | 1970 | Pediatrics | pmid:5468779 |
| Hoffmann GF et al. | Clinical and biochemical phenotype in 11 patients with mevalonic aciduria. | 1993 | Pediatrics | pmid:8386351 |
| Appelkvist EL et al. | Synthesis of mevalonate pathway lipids in fibroblasts from Zellweger and X-linked ALD patients. | 1999 | Pediatr. Res. | pmid:10473053 |
| Mancini J et al. | Mevalonic aciduria in 3 siblings: a new recognizable metabolic encephalopathy. | 1993 May-Jun | Pediatr. Neurol. | pmid:8352861 |
| Hamid PH et al. | Differential inhibition of host cell cholesterol de novo biosynthesis and processing abrogates Eimeria bovis intracellular development. | 2014 | Parasitol. Res. | pmid:25199551 |
| Haas D and Hoffmann GF | Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome. | 2006 | Orphanet J Rare Dis | pmid:16722536 |
| Qiu Y and Li D | Bifunctional inhibitors of mevalonate kinase and mevalonate 5-diphosphate decarboxylase. | 2006 | Org. Lett. | pmid:16524256 |
| Citron CA and Dickschat JS | The stereochemical course of tricho-acorenol biosynthesis. | 2013 | Org. Biomol. Chem. | pmid:24084795 |
| Wang T et al. | Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway. | 2016 | Oncotarget | pmid:26565813 |
| Pandyra AA et al. | Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death. | 2015 | Oncotarget | pmid:26353928 |
| Sharon C et al. | Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. | 2015 | Oncotarget | pmid:25895029 |
| Pampalakis G et al. | The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway. | 2014 | Oncotarget | pmid:24158494 |
| Löffler M and Schneider F | Unexpectedly low incorporation of isotopic acetate into lipids of Ehrlich ascites tumor cells cultured in lipid-poor medium. | 1979 | Oncology | pmid:37470 |
| Issat T et al. | Antitumor effects of the combination of cholesterol reducing drugs. | 2011 | Oncol. Rep. | pmid:21491092 |
| Issat T et al. | Berberine, a natural cholesterol reducing product, exerts antitumor cytostatic/cytotoxic effects independently from the mevalonate pathway. | 2006 | Oncol. Rep. | pmid:17089049 |
| Ghosh PM et al. | Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. | 1999 | Oncogene | pmid:10435593 |
| Shack S et al. | Activation of the cholesterol pathway and Ras maturation in response to stress. | 1999 | Oncogene | pmid:10557091 |
| Deichmann R et al. | Coenzyme q10 and statin-induced mitochondrial dysfunction. | 2010 | Ochsner J | pmid:21603349 |
| Cho SH et al. | Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller. | 2011 | Nutr Res Pract | pmid:22125678 |
| Wilson GJ et al. | Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. | 2008 | Nutr Metab (Lond) | pmid:18173841 |
| Conrado RJ et al. | DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. | 2012 | Nucleic Acids Res. | pmid:22021385 |
| Patel NV and Forman BM | Linking lipids, Alzheimer's and LXRs? | 2004 | Nucl Recept Signal | pmid:16604185 |
| Habara K et al. | Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. | 2008 | Nitric Oxide | pmid:17936042 |
| Yamashita Y et al. | A 6-year-old girl diagnosed with mevalonate kinase deficiency who had hydrops fetalis and neonatal-onset cholestasis. | 2017 | Nihon Rinsho Meneki Gakkai Kaishi | pmid:28603204 |
| Sakai H and Heike T | [Hyperimmunoglobulinemia D and periodic fever syndrome]. | 2011 | Nihon Rinsho Meneki Gakkai Kaishi | pmid:22041426 |
| Fabris M et al. | Tracking the sterol biosynthesis pathway of the diatom Phaeodactylum tricornutum. | 2014 | New Phytol. | pmid:24996048 |
| Mans RA et al. | Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. | 2012 | Neuroscience | pmid:22192838 |
| Tringali G et al. | Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase. | 2004 | Neurosci. Lett. | pmid:14698450 |
| Sato-Suzuki I and Murota S | Simvastatin inhibits the division and induces neurite-like outgrowth in PC12 cells. | 1996 | Neurosci. Lett. | pmid:8977139 |
| Woo IS et al. | Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. | 2010 | Neurosci. Lett. | pmid:20298756 |
| Kosztáczky B et al. | Neuropeptides induced a pronounced and statin-sensitive dysregulation of mevalonate cycle in human monocytes of patients with hypercholesterolemia. | 2006 | Neuropeptides | pmid:17049599 |
| Haas D et al. | Inherited disorders of cholesterol biosynthesis. | 2001 | Neuropediatrics | pmid:11521206 |
| Paoletti P et al. | Lipid biosynthesis from labelled precursors in an experimental brain tumor-bearing mouse. | 1966 | Neurochirurgia (Stuttg) | pmid:5966653 |
| Hosaka A et al. | Statins reduce amyloid β-peptide production by modulating amyloid precursor protein maturation and phosphorylation through a cholesterol-independent mechanism in cultured neurons. | 2013 | Neurochem. Res. | pmid:23269484 |
| Domoki F et al. | Rosuvastatin induces delayed preconditioning against L-glutamate excitotoxicity in cultured cortical neurons. | 2010 | Neurochem. Int. | pmid:19931334 |
| Hamano T et al. | Pitavastatin decreases tau levels via the inactivation of Rho/ROCK. | 2012 | Neurobiol. Aging | pmid:22133277 |
| Ikeuchi H et al. | Fluvastatin reduces renal fibroblast proliferation and production of type III collagen: therapeutic implications for tubulointerstitial fibrosis. | 2004 | Nephron Exp. Nephrol. | pmid:15331935 |