Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Glioblastoma D005909 27 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Hypothyroidism D007037 32 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Thrombosis D013927 49 associated lipids
Leukemia D007938 74 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Cartwright IJ et al. Investigation of the role of lipids in the assembly of very low density lipoproteins in rabbit hepatocytes. 1997 J. Lipid Res. pmid:9101434
pmid:9089010
Crick DC et al. Geranylgeraniol promotes entry of UT-2 cells into the cell cycle in the absence of mevalonate. 1997 Exp. Cell Res. pmid:9087171
Endo A et al. Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 1977 Eur. J. Biochem. pmid:908337
Colli S et al. Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9081680
pmid:9070894
Scoppola A et al. Plasma mevalonate concentrations in uremic patients. 1997 Kidney Int. pmid:9067929
pmid:9056235
Beytía ED and Porter JW Biochemistry of polyisoprenoid biosynthesis. 1976 Annu. Rev. Biochem. pmid:9026
Edwards PA et al. Preferential uptake and utilization of mevalonolactone over mevalonate for sterol biosynthesis in isolated rat hepatocytes. 1977 Biochim. Biophys. Acta pmid:901801
Peffley DM and Gayen AK Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level. 1997 Arch. Biochem. Biophys. pmid:9016820
Stout RW The effect of insulin and glucose on sterol synthesis in cultured rat arterial smooth muscle cells. 1977 Atherosclerosis pmid:901624
Lichtenthaler HK et al. Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. 1997 FEBS Lett. pmid:9009212
pmid:900481
Chiloeches A et al. Effect of mevalonate availability on the association of G-protein alpha-subunits with the plasma membrane in GH4C1 cells. 1997 FEBS Lett. pmid:9003808
Hirai A et al. Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells. 1997 J. Biol. Chem. pmid:8995216
Spicer LJ et al. Insulin-like growth factor I enhancement of steroidogenesis by bovine granulosa cells and thecal cells: dependence on de novo cholesterol synthesis. 1996 J. Endocrinol. pmid:8994382
Krisans SK Cell compartmentalization of cholesterol biosynthesis. 1996 Ann. N. Y. Acad. Sci. pmid:8993542
Shoda J et al. Simultaneous determination of plasma mevalonate and 7alpha-hydroxy-4-cholesten-3-one levels in hyperlipoproteinemia: convenient indices for estimating hepatic defects of cholesterol and bile acid syntheses and biliary cholesterol supersaturation. 1997 Hepatology pmid:8985259
Sato-Suzuki I and Murota S Simvastatin inhibits the division and induces neurite-like outgrowth in PC12 cells. 1996 Neurosci. Lett. pmid:8977139