Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Wong WW et al. Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma. 2007 Mol. Cancer Ther. pmid:17575117
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Bretón Martínez JR et al. Mevalonic aciduria: report of two cases. 2007 J. Inherit. Metab. Dis. pmid:17578678
Byres E et al. Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. 2007 J. Mol. Biol. pmid:17583736
Hamadmad SN and Hohl RJ Lovastatin suppresses erythropoietin receptor surface expression through dual inhibition of glycosylation and geranylgeranylation. 2007 Biochem. Pharmacol. pmid:17586475
Haas D and Hoffmann GF Mevalonate kinase deficiency and autoinflammatory disorders. 2007 N. Engl. J. Med. pmid:17596600
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Kinjoh T et al. Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata. 2007 Insect Biochem. Mol. Biol. pmid:17628279
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Ramachandran CK and Shah SN Decarboxylation of mevalonate pyrophosphate is one rate-limiting step in hepatic cholesterol synthesis in suckling and weaned rats. 1976 Biochem. Biophys. Res. Commun. pmid:177019
Towler MJ and Weathers PJ Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. 2007 Plant Cell Rep. pmid:17710406
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Ong KK et al. Assay of 3-hydroxy-3-methylglutaryl CoA reductase activity using anionic-exchange column chromatography. 1991 Anal. Biochem. pmid:1776669
Ye J Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus. 2007 PLoS Pathog. pmid:17784784
Baldi A and Dixit VK Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua. 2008 Bioresour. Technol. pmid:17804216
Zeiser R et al. Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity. 2007 Blood pmid:17827390
Mönkkönen H et al. Zoledronic acid-induced IPP/ApppI production in vivo. 2007 Life Sci. pmid:17850825
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Arkwright PD et al. Mevalonic aciduria cured by bone marrow transplantation. 2007 N. Engl. J. Med. pmid:17898110
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Tekle M et al. Investigation of coenzyme Q biosynthesis in human fibroblast and HepG2 cells. 2008 J. Biochem. Biophys. Methods pmid:17916383
Ohyama K et al. Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis. 2007 Chem. Pharm. Bull. pmid:17917299
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Jantzen F et al. Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells. 2007 J. Physiol. Pharmacol. pmid:17928646
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Nakao T et al. Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling. 2007 J. Pharmacol. Sci. pmid:18057776
Liang YJ et al. Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products. 2008 Cardiology pmid:18057884
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Lazzerini PE et al. Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. 2007 Sep-Oct Clin. Exp. Rheumatol. pmid:18078616
Sarrabayrouse G et al. Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells. 2007 Neoplasia pmid:18084615
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Osman L et al. Atorvastatin accelerates extracellular nucleotide degradation in human endothelial cells. 2008 Mol. Cell. Biochem. pmid:18158588
Couillaud F Evidence for regulation of juvenile hormone biosynthesis operating before mevalonate in locust corpora allata. 1991 Mol. Cell. Endocrinol. pmid:1815999
Wilson GJ et al. Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. 2008 Nutr Metab (Lond) pmid:18173841
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Glynn SA et al. The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. 2008 BMC Cancer pmid:18199328
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Deanin GG et al. Role of isoprenoid metabolism in IgE receptor-mediated signal transduction. 1991 J. Immunol. pmid:1827487
Okada K et al. Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. 2008 Plant Cell Physiol. pmid:18303110
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Carrasco MP et al. Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells. 2008 FEBS J. pmid:18312412
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Schulz S and Nyce JW Inhibition of protein isoprenylation and p21ras membrane association by dehydroepiandrosterone in human colonic adenocarcinoma cells in vitro. 1991 Cancer Res. pmid:1835900
Park SY et al. Inhibitory effect of simvastatin on the TNF-alpha- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation. 2008 Arch. Pharm. Res. pmid:18365690
Winiarska M et al. Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. 2008 PLoS Med. pmid:18366248
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Ogunwobi OO and Beales IL Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. 2008 Am. J. Gastroenterol. pmid:18371146
Martin-Ventura JL et al. LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin. 2008 Atherosclerosis pmid:18378243
de Ruyck J and Wouters J Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. 2008 Curr. Protein Pept. Sci. pmid:18393884
Kettawan A et al. Protective effects of coenzyme q(10) on decreased oxidative stress resistance induced by simvastatin. 2007 J Clin Biochem Nutr pmid:18398496
Tarhzaoui K et al. Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetes. 2008 Diabetes Res. Clin. Pract. pmid:18406000
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Zhang X et al. Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. 2008 J. Immunol. pmid:18453621
Shimizu S et al. Possible involvement of 3-hydroxymethylglutaryl-CoA reductase in determining the side-chain length of ubiquinone in rat heart. 1991 Arch. Biochem. Biophys. pmid:1846516
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Skorupinska-Tudek K et al. Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. 2008 J. Biol. Chem. pmid:18502754
Simonen M et al. High-content assay to study protein prenylation. 2008 J Biomol Screen pmid:18509097
Sharyo S et al. Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. 2008 Kidney Int. pmid:18509318
Udagawa H et al. Increase of serum cholesterol levels by heat-moisture-treated high-amylose cornstarch in rats fed a high-cholesterol diet. 2008 Lipids pmid:18509689
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Fried LF Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease. 2008 Kidney Int. pmid:18528321
Chana RS et al. Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis. 2008 Am. J. Nephrol. pmid:18535368
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Matsuda T et al. Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells. 2008 J. Pharmacol. Exp. Ther. pmid:18593956
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