Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Hypertension D006973 115 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia D007938 74 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Peutz-Jeghers Syndrome D010580 2 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Goldman AR et al. The Primary Effect on the Proteome of ARID1A-mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-transcriptional Level. 2016 Mol. Cell Proteomics pmid:27654507
Wang J et al. Engineering of a Highly Efficient Escherichia coli Strain for Mevalonate Fermentation through Chromosomal Integration. 2016 Appl. Environ. Microbiol. pmid:27736790
Parrales A et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. 2016 Nat. Cell Biol. pmid:27775703
Ruiz-Sola MÁ et al. A Single Arabidopsis Gene Encodes Two Differentially Targeted Geranylgeranyl Diphosphate Synthase Isoforms. 2016 Plant Physiol. pmid:27707890
Miettinen TP and Björklund M Cellular Allometry of Mitochondrial Functionality Establishes the Optimal Cell Size. 2016 Dev. Cell pmid:27720611
Yamamoto K et al. Enhancement of astaxanthin production in Xanthophyllomyces dendrorhous by efficient method for the complete deletion of genes. 2016 Microb. Cell Fact. pmid:27624332
Nerdal PT et al. Butyrophilin 3A/CD277-Dependent Activation of Human γδ T Cells: Accessory Cell Capacity of Distinct Leukocyte Populations. 2016 J. Immunol. pmid:27619996
Terabe K et al. Simvastatin inhibits CD44 fragmentation in chondrocytes. 2016 Arch. Biochem. Biophys. pmid:27242325
Healey GD et al. Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis. 2016 J. Immunol. pmid:26673142
Torabi S and Mo H Trans, trans-farnesol as a mevalonate-derived inducer of murine 3T3-F442A pre-adipocyte differentiation. 2016 Exp. Biol. Med. (Maywood) pmid:26660152
Jiang Z et al. Engineering Triterpene and Methylated Triterpene Production in Plants Provides Biochemical and Physiological Insights into Terpene Metabolism. 2016 Plant Physiol. pmid:26603654
Mertens J et al. The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula. 2016 Plant Physiol. pmid:26589673
Garnett DJ Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer. 2016 J. Cancer Res. Clin. Oncol. pmid:26573510
Nyati P et al. Negative Feedbacks by Isoprenoids on a Mevalonate Kinase Expressed in the Corpora Allata of Mosquitoes. 2015 PLoS ONE pmid:26566274
Chen Y et al. Mevalonate inhibits acid sphingomyelinase activity, increases sphingomyelin levels and inhibits cell proliferation of HepG2 and Caco-2 cells. 2015 Lipids Health Dis pmid:26493087
Laezza C et al. p53 regulates the mevalonate pathway in human glioblastoma multiforme. 2015 Cell Death Dis pmid:26469958
Rondini EA et al. Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes. 2015 J. Pharmacol. Exp. Ther. pmid:26427720
Kang S et al. Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. 2015 Eur J Med Chem pmid:25461893
Matsuo S et al. Single-dose rosuvastatin ameliorates lung ischemia-reperfusion injury via upregulation of endothelial nitric oxide synthase and inhibition of macrophage infiltration in rats with pulmonary hypertension. 2015 J. Thorac. Cardiovasc. Surg. pmid:25454916
Vinokur JM et al. Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. 2015 Protein Sci. pmid:25422158