Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Hypertension D006973 115 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia D007938 74 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Peutz-Jeghers Syndrome D010580 2 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Yildirim FI et al. Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. 2015 Prostaglandins Other Lipid Mediat. pmid:26201058
Kabara JJ A critical review of brain cholesterol metabolism. 1973 Prog. Brain Res. pmid:4608424
Popják G and Meenan A Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase: search for the enzyme's repressor derived from mevalonate. 1987 Proc. R. Soc. Lond., B, Biol. Sci. pmid:2892200
Cornforth J Symmetry of squalene epoxidation in vivo. 1977 Proc. R. Soc. Lond., B, Biol. Sci. pmid:22855
Pronin AN and Gautam N Interaction between G-protein beta and gamma subunit types is selective. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1631113
Liu GC et al. Measurement of cholesterol synthesis in man by isotope kinetics of squalene. 1975 Proc. Natl. Acad. Sci. U.S.A. pmid:1060141
Kotti T et al. Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18685105
Jakóbisiak M et al. Cell cycle-specific effects of lovastatin. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1673788
Jackson JH et al. Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. 1990 Proc. Natl. Acad. Sci. U.S.A. pmid:2183224
Tianero MD et al. Metabolic model for diversity-generating biosynthesis. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:26831074
Goldstein JL and Brown MS Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. 1973 Proc. Natl. Acad. Sci. U.S.A. pmid:4355366
Xiong M et al. Scalable production of mechanically tunable block polymers from sugar. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:24912182
Mumby SM et al. G protein gamma subunits contain a 20-carbon isoprenoid. 1990 Proc. Natl. Acad. Sci. U.S.A. pmid:2116011
Stone KJ and Strominger JL Inhibition of sterol biosynthesis by bacitracin. 1972 Proc. Natl. Acad. Sci. U.S.A. pmid:4338587
Kotti TJ et al. Brain cholesterol turnover required for geranylgeraniol production and learning in mice. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16505352
Khosravi-Far R et al. Isoprenoid modification of rab proteins terminating in CC or CXC motifs. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1648736
Loiseau L et al. ErpA, an iron sulfur (Fe S) protein of the A-type essential for respiratory metabolism in Escherichia coli. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:17698959
Lange BM et al. A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9482845
Rao S et al. Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10393901
Beg ZH et al. In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6594693