Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Hypertension D006973 115 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Glioma D005910 112 associated lipids
Glioblastoma D005909 27 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Nerdal PT et al. Butyrophilin 3A/CD277-Dependent Activation of Human γδ T Cells: Accessory Cell Capacity of Distinct Leukocyte Populations. 2016 J. Immunol. pmid:27619996
Terabe K et al. Simvastatin inhibits CD44 fragmentation in chondrocytes. 2016 Arch. Biochem. Biophys. pmid:27242325
Agabiti SS et al. Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation. 2016 Mol. Membr. Biol. pmid:27537059
Rizvi F et al. Chamber-specific differences in human cardiac fibroblast proliferation and responsiveness toward simvastatin. 2016 Am. J. Physiol., Cell Physiol. pmid:27335167
Elsayed M et al. Synergistic Antiproliferative Effects of Zoledronic Acid and Fluvastatin on Human Pancreatic Cancer Cell Lines: An in Vitro Study. 2016 Biol. Pharm. Bull. pmid:27181081
Silva Ramos E et al. Bioenergetic roles of mitochondrial fusion. 2016 Biochim. Biophys. Acta pmid:27060252
Leitmeyer K et al. Simvastatin Results in a Dose-Dependent Toxic Effect on Spiral Ganglion Neurons in an In Vitro Organotypic Culture Assay. 2016 Biomed Res Int pmid:27051663
Hashimoto A et al. P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance. 2016 J. Cell Biol. pmid:27044891
Cheng S et al. Cloning, Expression Profiling and Functional Analysis of CnHMGS, a Gene Encoding 3-hydroxy-3-Methylglutaryl Coenzyme A Synthase from Chamaemelum nobile. 2016 Molecules pmid:27005600
Okin D and Medzhitov R The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia. 2016 Cell pmid:26997483
Salunkhe VA et al. Rosuvastatin Treatment Affects Both Basal and Glucose-Induced Insulin Secretion in INS-1 832/13 Cells. 2016 PLoS ONE pmid:26986474
Marcuzzi A et al. Geranylgeraniol and Neurological Impairment: Involvement of Apoptosis and Mitochondrial Morphology. 2016 Int J Mol Sci pmid:26978350
Wang T et al. Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway. 2016 Oncotarget pmid:26565813
Yildirim FI et al. Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. 2015 Prostaglandins Other Lipid Mediat. pmid:26201058
Zhang Z et al. Genomic variations of the mevalonate pathway in porokeratosis. 2015 Elife pmid:26202976
Venkateshwaran M et al. A role for the mevalonate pathway in early plant symbiotic signaling. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26199419
Tricarico PM et al. Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link. 2015 Int J Mol Sci pmid:26184189
Kobayashi Y et al. Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models. 2015 Clin. Cancer Res. pmid:26109099
Tricarico PM et al. Alendronate, a double-edged sword acting in the mevalonate pathway. 2015 Mol Med Rep pmid:26096667
Hofberger JA et al. Large-Scale Evolutionary Analysis of Genes and Supergene Clusters from Terpenoid Modular Pathways Provides Insights into Metabolic Diversification in Flowering Plants. 2015 PLoS ONE pmid:26046541